Treatment for hyperparathyroidism with use of vitamin D derivatives
First Claim
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1. A method for treating hyperparathyroidism comprising administering to a patient suffering from hyperparathyroidism an effective amount of a 1α
- -hydroxyvitamin D derivative of formula (I);
##STR4## wherein R is a branched alkyl group having 4-6 carbon atoms that is substituted by one or two hydroxyl groups or a cyclopropylhydroxymethyl group.
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Abstract
A treatment for hyperparathyroidism with use of a 1α-hydroxyvitamin D derivative of the formula (I) ##STR1## wherein R is a branched alkyl group having 4-6 carbon atoms that is substituted by one or two hydroxyl groups or a cyclopropylhydroxymethyl group, are disclosed. A pharmaceutical composition comprising the above derivatives is useful as a therapeutic agent for hyperparathyroidism such as secondary hyperparathyroidism.
50 Citations
11 Claims
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1. A method for treating hyperparathyroidism comprising administering to a patient suffering from hyperparathyroidism an effective amount of a 1α
- -hydroxyvitamin D derivative of formula (I);
##STR4## wherein R is a branched alkyl group having 4-6 carbon atoms that is substituted by one or two hydroxyl groups or a cyclopropylhydroxymethyl group. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
- -hydroxyvitamin D derivative of formula (I);
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Current AssigneeChugai Seiyaku Kabushiki Kaisha (Roche Holding AG)
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Original AssigneeChugai Seiyaku Kabushiki Kaisha (Roche Holding AG)
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InventorsTakita, Yumiko, Nishii, Yasuho
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Primary Examiner(s)Waddell, Frederick E.
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Assistant Examiner(s)CRIARES, THEODORE J
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Application NumberUS07/501,226Time in Patent Office586 DaysField of Search514/167, 552/653US Class Current514/167CPC Class CodesA61K 31/59 Compounds containing 9, 10-...
