Ambulatory syringe-pusher device for parenteral injections with output servo-controlled by the contents of the syringe

• US 5,139,484 A
• Filed: 09/10/1990
• Issued: 08/18/1992
• Est. Priority Date: 01/07/1988
• Status: Expired due to Fees

• Current Assignee: Hazon Bernard
• Original Assignee: Bernard Hazon
• Inventors: Hazon, Bernard, Sausse, heir, Jean-Claude, Sausse, deceased, Andre
• Primary Examiner(s): Mancene, Gene
• Assistant Examiner(s): Lynch, Michael
• Application Number:
  US07/536,637
• Time in Patent Office: 708 Days
• Field of Search: 604/151, 604/152, 604/153, 604/154, 604/155, 604/65, 604/67, 128/DIG. 1, 128/DIG. 12
• US Class Current: 604/154
• CPC Class Codes: A61M 5/1456 with a replaceable reservoir comprising a piston rod to be moved into the reservoir, e.g. the piston rod is part of the removable reservoir
• CPC Class Codes: Y10S 128/01 Motorized syringe

Abstract

This invention relates to a syringe-pusher device for ambulatory treatment, automatically delivering in a constant time compatible with the circadian rhythms, a fixed number of elementary volumes varying as a function of the prior filling volume of the syringe used by the operator. Said volume generally corresponding to the daily dose of drug can be directly read on the graduations on the syringe. A sound alarm is set off in the event of an impediment to the flow of the fluid as well as in the event of the untimely injection of elementary volume outside the set program.

Claims

1. In a syringe-pusher device having a syringe for containing a volume of material therein for injection for ambulatory treatment, said device employing a coaxial D.C. motor, a reduction gear including an endless screw, an improved system for distributing a plurality of elementary volumes or boluses separated in time by periods of relaxation in response to the rotation of said screw which comprises means for operating said motor for providing an output corresponding only to the height of material of indifferentiated type introduced into said syringe prior to injection, and servo-control means responsive to said output for operating said motor at times separated by said periods to control the mean output of said material injected by said syringe.

2. The device of claim 1 wherein aid servo-control means includes means for automatic adjustment of the elementary volume proportionately to any volume introduced into the syringe of indifferentiated type prior to injection.

3. The device of claim 1 wherein said servo-control means includes automatic adjustment means responsive to the number of elementary volumes of constant volume proportionally to the volume introduced in the syringe of indifferentiated type prior to injection.

4. The device of claim 1 wherein aid syringe has a piston-pusher member operably connected to said endless screw, and said control means for said motor comprises a reversible counter which integrates the positive and negative revolutions of the motor.

5. The device according to claim 4 wherein said control means includes means for controlling the instantaneous position of the piston pusher member and comprises a potentiometer having a slide mechanically fast with said pusher member.

6. The device of claim 5 wherein the position of said piston-pusher member is calibrated and further comprising means for recording the positions of the piston pusher member when the syringe is completely empty, and then when the syringe is charged with the chosen volume, and the calibrated distance between these positions of the piston pusher member.

7. The device of claim 1 wherein aid syringe has a piston and a piston-pusher member extending therefrom, the maximum possible stroke of the piston-pusher member being divided into two unequal segments, said piston-pusher member being always disposed in the shorter of said segments when it is in physical contact with the piston of said syringe when completely empty.

8. The device of claim 1 wherein said motor operating means comprises a clock and means for initiation for rotation of the motor on the control of the clock, said motor having an armature and said piston-pusher displacement being calibrated from an initiation location, and means for controlling the stopping of the motor by short circuiting said armature comprising means for comparison of the number of revolutions described by the motor rom said initiation with the datum issued from the calibrated positions of said piston-pusher member.

9. The device of claim 8 wherein said means for controlling said stopping comprises means for the integration of the revolutions or fractions of revolution of the motor after every initiation of the clock is obtained, said integration means comprising a preconfigurable counter.

10. The device of claim 9 wherein said stopping control means comprises means for dividing the datum recorded form the counter during the calibration by the total number of elementary volumes and by a factor function of the reduction ratio of the reduction gear and of the revolutions of the motor to provide a count, and means for presetting the preconfigurable counter with said count.

11. The device of claim 1 wherein said motor has a collector with two consecutive blades which contact brushes, and means for the integration of the revolutions or fractions of revolution of said motor comprises means for short circuiting the two consecutive blades of the collector during its passage between one of the brushes to provide signals and integrating said signals.

12. The device of claim 11 further comprising a component which affects the passage of signals, and wherein the signals coming from the short circuiting means are collected at the terminals of the component, said motor having an armature in series with said inductor or resistor.

13. The device of claim 12 further comprising means responsive to the signals collected at the terminals of the inductor or the resistor for discriminating said signals in accordance with the polarity, frequency and amplitude thereof in at least three orders of response to the variation of the intensity of said signals appearing across said armature.

14. The device of claim 13 further comprising means for integrating the signals of first order in accordance with the polarity thereof for the entire duration of the calibration and injection operations of said device, said integrating means comprising a reversible counter.

15. The device of claim 14 further comprising a preconfigurable counter said reversible counter being responsive to signals of first order of one polarity during injection operations for presetting the preconfigurable counter.

16. The device of claim 15 wherein said piston-pusher controls a piston of said syringe and the stroke of said pusher has unequal front and rear segments over which it is displaced and further comprising means responsive to the signals of second order and of a polarity characteristic representing the physical contact of the piston-pusher and of the piston to provoke during calibration on the front short segment before return to zero of the reversible counter and immediately thereafter, the general cut off of operating voltage to said motor, and in the real long segment, the initiation of the injection operations.

17. The device of claim 16 wherein said device has a safety system providing a timed sound alarm, and further comprising means responsive to the signals of third order of one polarity to provoke the stoppage of said motor and the operation of said safety system.

18. The device of claim 1 wherein said control means comprises a clock and an integrator of the revolutions or fractions of revolution of the endless screw and mechanically fast therewith which counts the number of elementary volumes delivered further to every initiation of said motor by the clock.

19. The device of claim 18 wherein said control means includes means for the counting of two elementary volumes immediately consecutive to an initiation of the clock which irrevocably stops the motor and excites a permanent signal for placing the device out of service.

20. The device of claim 19 wherein the integrator of revolutions or fractions of revolution of the endless screw is formed by a permanent rotating magnet fixed mechanically at the end of the endless screw and acting remotely on an element sensitive to magnetism.