Demand apnea control of central and obstructive sleep apnea

• US 5,146,918 A
• Filed: 03/19/1991
• Issued: 09/15/1992
• Est. Priority Date: 03/19/1991
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Markowitz, H. Toby, Kallok, Michael J.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): JASTRZAB, JEFFREY R
• Application Number:
  US07/671,513
• Time in Patent Office: 546 Days
• Field of Search: 128/419 G, 128/421, 128/720-721, 128/716, 128/204.23
• US Class Current: 607/2
• CPC Class Codes: A61N 1/3601 of respiratory organs

Abstract

An apparatus and method for the control of both central and obstructive sleep apnea using electrical stimulation on a demand basis. Implantable sensors monitor the respiration cycle and determine the occurrence of apnea events. Central apnea is sensed by the passage of an escape interval of time without the sensing of an inspiratory event and a concurrent decrease in blood oxygen saturation. Obstructive sleep apnea is sensed as an abnormal pressure differential across the airway. The diaphragm is electrically stimulated upon sensing of central apnea. The musculature of the upper airway is electrically stimulated upon sensing of an occurrence of obstructive sleep apnea. Stimulation of the upper airway is provided whenever central apnea is sensed.

Claims

1. An apparatus comprising:

a. first means for sensing a central apnea event;

b. first means responsibly coupled to said first sensing means for providing stimulation to a diaphragm of a patient in response to sensing of said central apnea event;

c. second means coupled to said first sensing means for sensing an obstructive apnea event; and

,

d. second means coupled to said second sensing means for generating electrical stimulation of muscles of said patient in response to sensing by said second sensing means of said obstructive apnea event.

2. An apparatus according to claim 1 wherein said first sensing means further comprises a pressure sensor.

3. An apparatus according to claim 2 wherein said second sensing means comprises a pressure sensor.

4. An apparatus according to claim 3 wherein said first sensing means further comprises a first threshold circuit.

5. An apparatus according to claim 4 wherein said second sensing means further comprises a second threshold circuit.

6. An apparatus according to claim 1 wherein said first sensing means comprises a means for measuring blood oxygen.

7. An apparatus according to claim 6 wherein said measuring means comprises a reflectance oximeter.

8. An apparatus according to claim 1 wherein said first sensing means comprises means for determining a plurality of conditions related to apnea.

9. An apparatus according to claim 8 wherein said determining means comprises an oximeter.

10. An apparatus according to claim 8 wherein said determining means comprises a pressure sensor.

11. An apparatus according to claim 8 wherein said determining means comprises a nerve electrode.

12. A method of treating a patient comprising:

a. sensing pressure within an upper airway of said patient;

b. assuming a central apnea event if said pressure does not reach a first threshold within a predetermined period of time;

c. electrically stimulating a diaphragm of said patient in response to said central apnea event assumption;

d. assuming an obstructive apnea event if said pressure reaches a second threshold; and

,

e. electrically stimulating muscles of said patient in response to said assuming said obstructive apnea event.