Surface-modified self-passivating intraocular lenses
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1. An intraocular lens, comprising an optic bearing a coating comprising C12 -C36 alkyl groups, whereby said optic exhibits enhanced ability to adsorb and retain albumin.
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Abstract
The invention relates to intraocular lenses coated with C12 -C36 alkyl groups that render the surface of the intraocular lens less prone to causing inflammation after implantation of the intraocular lens. The alkyl groups may be coated on the IOL by a centrifugal casting method, a solution deposition method (e.g., a covalent attachment method), or a plasma deposition method that minimizes fragmentation of the alkyl groups.
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19 Claims
- 1. An intraocular lens, comprising an optic bearing a coating comprising C12 -C36 alkyl groups, whereby said optic exhibits enhanced ability to adsorb and retain albumin.
- 12. A method of enhancing biocompatability of an intraocular lens comprising an optic, which method comprises applying to said optic a coating comprising C12 -C36 alkyl groups, whereby said optic exhibits enhanced ability to adsorb and retain albumin.
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