Fluid dispenser for germ-free fluid

• US 5,232,687 A
• Filed: 08/02/1991
• Issued: 08/03/1993
• Est. Priority Date: 08/29/1990
• Status: Expired due to Term

• Current Assignee: Ursapharm Arzneimittel GmbH
• Original Assignee: Ursapharm Arzneimittel GmbH
• Inventors: Geimer, Gunter
• Primary Examiner(s): Page, Thurman K.
• Assistant Examiner(s): LEVY, NEIL S
• Application Number:
  US07/739,918
• Time in Patent Office: 732 Days
• Field of Search: 424/405, 424/618, 424/619, 424/45, 128/DIG. 1, 128/DIG. 7, 128/DIG. 10, 128/DIG. 13, 128/474, 128/912, 128/917, 128/655, 604/33, 604/38, 604/123, 604/207
• US Class Current: 424/45
• CPC Class Codes: A61F 9/0008 Introducing ophthalmic products into the ocular cavity or retaining products therein putting in contact lenses A61F9/0061; introducing or retaining media in cavities of the body in general A61M31/00
• CPC Class Codes: A61J 1/1443 Containers with means for dispensing liquid medicaments in a filtered or sterile way, e.g. with bacterial filters
• CPC Class Codes: A61J 1/1468 Containers characterised by specific material properties
• CPC Class Codes: A61L 2/16 using chemical substances
• CPC Class Codes: B05B 11/0005 Components or details of single units wherein the flow is effected by a pump B05B11/1042
• CPC Class Codes: B05B 11/1001 Piston pumps B05B11/1087, B05B11/1088, B05B11/109 take precedence
• CPC Class Codes: B05B 11/104 the outlet valve being opened by pressure after a defined accumulation stroke

Abstract

A fluid dispenser incorporating an oligodynamically germicidally active substance for maintaining the dispensation of germ-free fluid, particularly eye drops. The delivery passage from a supply container associated with the fluid dispenser of the invention contains an oligodynamically germicidally active substance that is soluble in the fluid to be dispensed. The device does not require air pressure within the container, thus eliminating one avenue for the introduction of germs into the fluid. The device includes a metering pump and inlet and outlet valves. The above-mentioned fluid soluble oligodynamically germicidally active substance is situated in the region of the inlet valve or the inlet thereto and/or the outlet therefrom.

Claims

1. A fluid dispenser for germ-free fluid, comprising a through passage connecting an inlet opening for fluid contained in a supply container and a delivery opening for said fluid and having therein an oligodynamically germicidally active substance that is soluble in the fluid, said device comprising a metering pump operating without air pressure compensation and having an inlet valve for closing said inlet opening and having said fluid-soluble oligodynamically germicidally active substance embedded in a carrier material contained in at least one of said inlet valve and its associated inlet and outlet passages;

an outlet valve for closing said delivery opening, wherein said oligodynamically germicidally active substance is embedded in a carrier material contained in at least one of said outlet valve and its associated inlet and outlet passages;

said outlet valve including a closure member which contains a carrier material having said oligodynamically germicidally active substance embedded therein; and

at least one spring means acting on the closure member of the outlet valve, said at least one spring means having said oligodynamically germicidally active substance embedded in a carrier material on at least on a surface thereof.

2. A fluid dispenser according to claim 1, wherein said through passage is constantly filled, at least in the region of said inlet valve, with said fluid.

3. A fluid dispenser according to claim 1, wherein said oligodynamically germicidally active substance is situated on the inner side of a cap that can be fitted on to said fluid dispenser to cover said delivery opening.

4. A fluid dispenser according to claim 1, wherein said inlet valve includes a closure member which contains said oligodynamically germicidally active substance.

5. A fluid dispenser according to claim 4, wherein said inlet valve further includes a valve seat cooperating with the closure member wherein said valve seat contains said oligodynamically germicidally active substance.

6. A fluid dispenser according to claim 1, wherein said outlet valve further includes a valve seat cooperating with the closure member wherein said valve seat contains said oligodynamically germicidally active substance.

7. A fluid dispenser according to claim 1, wherein said inlet valve is a piston valve and a valve housing cooperating with a closure member of said inlet valve, said valve housing containing said oligodynamically germicidally active substance.

8. A fluid dispenser according to claim 1, wherein said outlet valve is a piston valve and a valve housing cooperating with a closure member of said outlet valve, said valve housing containing said oligodynamically germicidally active substance.

9. A fluid dispenser according to claim 4 which includes at least on spring acting one the closure member of the inlet valve said at least one spring having said oligodynamically germicidally active substance situated at least on a surface thereof.

10. A fluid dispenser according to claim 2, wherein at least a surface of at least part of a rising tube forming an inlet passage to said inlet valve contains said oligodynamically germicidally active substance.

11. A fluid dispenser according to claim 1, wherein at least a surface of at least part of said through passage in the region between said inlet and outlet valves contains said oligodynamically germicidally active substance.

12. A fluid dispenser according to claim 1, wherein said carrier material is corundum.

13. A fluid dispenser according to claim 1, wherein said oligodynamically germicidally active substance is selected from the group consisting of heavy metals and alloys thereof.

14. A fluid dispenser according to claim 13, wherein said oligodynamically germicidally active substance is selected from the group consisting of heavy metals and alloys thereof in metallic form.

15. A fluid dispenser according to claim 13, wherein said oligodynamically germicidally active substance is selected from the group consisting of heavy metals and alloys thereof in the form of a compound such as a salt.

16. A fluid dispenser according to claim 13, wherein said oligodynamically germicidally active substance is selected from the group consisting of silver, silver salts and other silver compounds.