Intracavity ultrasonic device for elasticity imaging

• US 5,265,612 A
• Filed: 12/21/1992
• Issued: 11/30/1993
• Est. Priority Date: 12/21/1992
• Status: Expired due to Term

• Current Assignee: ProUroCare Medical, Inc.
• Original Assignee: Medical Biophysics International
• Inventors: Emelianov, Stanislav, Sarvazyan, Armen P., Skovoroda, Andrei R.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): MANUEL, GEORGE C
• Application Number:
  US07/994,105
• Time in Patent Office: 344 Days
• Field of Search: 128/660.01, 128/660.07, 128/660.06, 128/660.02, 128/662.06, 128/661.03
• US Class Current: 600/471
• CPC Class Codes: A61B 5/036 by means introduced into body tracts A61B5/032 and A61B5/035 take precedence
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence
• CPC Class Codes: A61B 8/12 in body cavities or body tracts, e.g. by using catheters catheters per se A61M25/00
• CPC Class Codes: A61B 8/445 Details of catheter construction
• CPC Class Codes: A61B 8/485 involving measuring strain or elastic properties

Abstract

An intracavity ultrasonic device for elasticity imaging of human tissue to obtain palpation information in a quantitative form by using a probe that has an ultrasonic transducer at one end thereof, the probe having a small diameter and being capable of being inserted inside a conduit of a body. An outer elastic sheath surrounds the probe and is sealed so that it can be filled with a fluid under pressure to create a chamber surrounding the ultrasonic transducer while the sheath is on the interior of the bodily conduit to be examined. By regulating the interior pressure, the sheath can be made to expand against the interior of the conduit and change the deformation of the tissue forming the conduit. The sheath includes a region of greater elasticity adjacent the transducer to facilitate localized deformation of a selected region of the bodily conduit wall. Obtaining images of the selected conduit region before and after compression provides data to calculate the elasticity of tissue in that region and surrounding regions. Elasticity is an informative characteristic for tumor detection as is known from the palpation technique of detecting tumors.

Claims

1. An device for palpating tissue comprising:

an extra candy probe an imaging transducer adjacent one end thereof;

said probe being of size to fit in within a bodily conduit to examined;

an outer sheath of expandable elastic material placed over the transducer and an end of the, probe to be inserted in the bodily conduit;

means for providing an internal fluid under pressure within the sheath between the probe and an inner surface of the sheath to provide expansion of the sheath to at least partially engage the interior surface of the bodily conduit and compress a conduit wall and tissue adjacent to the conduit wall; and

control means for operating the transducer at selected times correlated to the application of compression to the tissue for determining elasticity characteristics of tissue being imaged by the transducer.

2. The device as specified in claim 1, comprising pressure control means for controlling the pressure of the fluid on the interior of the sheath to at least two separate pressures.

3. The device of claim 1 wherein said sheath has a portion in a region adjacent to the transducer and the probe that is less resistant to expansion under fluid pressure to cause increased deformation of tissue in such region.

4. A method of quantitatively obtaining palpation information of tissue surrounding a bodily conduit, said conduit having a wall made of tissue and being within surrounding tissue comprising the steps of:

inserting a probe assembly into the bodily conduit, said probe assembly including a transducer for imaging bodily tissue;

providing an outer sheath over the probe that is flexible and capable of being expanded to engage the wall of the bodily conduit and cause compression of such wall and tissue surrounding the walls;

introducing a fluid under pressure on the interior of the flexible sheath to expand the sheath and compress tissue in at least localized areas contacted by the probe; and

obtaining images of tissue that correlate to the elasticity of the tissue before deforming the tissue, and subsequent to deforming the tissue.

5. The method claim 4 wherein the obtaining of the images is accomplished with moving the probe along the bodily conduit and making a three-dimensional reconstruction of the imaged tissue under different compression loadings, and calculating elastic moduli of tissues.

6. The method of claim 4 including the step of altering the compression in a selected sequence of steps and obtaining images at each successive step for analyzing the elasticity of tissue being imaged.