Method and apparatus for diagnosis of sleep disorders

• US 5,275,159 A
• Filed: 03/20/1992
• Issued: 01/04/1994
• Est. Priority Date: 03/22/1991
• Status: Expired due to Term

• Current Assignee: Map Medizintechnik Fur ARZT und Patient GmbH
• Original Assignee: Madaus Schwarzer Medizintechnik GmbH & Co. KG
• Inventors: Griebel, Peter
• Primary Examiner(s): Howell, Kyle L.
• Assistant Examiner(s): NASSER, ROBERT L
• Application Number:
  US07/854,241
• Time in Patent Office: 655 Days
• Field of Search: 128/670, 128/671, 128/630, 128/633, 128/706, 128/709, 128/710, 128/716, 128/666
• US Class Current: 600/324
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/02427 Details of sensor
• CPC Class Codes: A61B 5/0816 Measuring devices for examining respiratory frequency measuring frequency of electric signals G01R23/00
• CPC Class Codes: A61B 5/14552 Details of sensors specially adapted therefor
• CPC Class Codes: A61B 5/332 Portable devices specially adapted therefor
• CPC Class Codes: A61B 5/352 Detecting R peaks, e.g. for synchronising diagnostic apparatus; Estimating R-R interval
• CPC Class Codes: A61B 5/4818 Sleep apnoea
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 7/003 Detecting lung or respiration noise

Abstract

The physiological parameters of heart rate, respiratory and snoring sounds, the degree of oxygen saturation of the blood, and the bodily position of the patient are measured and stored in coded form by means of portable apparatus. The stored data are transferred to a computer and then analyzed. The mobile apparatus comprises a detection and storage unit (2) and the following pickups: three EKG electrodes (3), one laryngeal microphone (4), an oximeter-finger sensor (5) and a position pickup (6). The apparatus permits an ambulatory diagnosis of sleep apnea which is comparable in its meaningfulness to diagnoses based on stationary sleep laboratory tests for sleep apnea.

Claims

1. Method for the ambulatory detection and diagnosis of sleep disorders in a patient, comprising

sensing heart potentials and generating a heart rate signal,

sensing respiratory sounds and generating loud breathing signal and a snoring signal from said respiratory sounds,

sensing degree of oxygen saturation in the patient'"'"'s blood and generating an oxygen saturation signal,

storing said heart rate signal, loud breathing signal, snoring signal, and oxygen saturation signal over time as stored signals, and

comparing said stored signals to determine whether each one of obstructive sleep apnea, central apnea, continuous snoring, upper airway resistance syndrome, and nocturnal myoclonus is present.

2. Method as in claim 1 wherein obstructive sleep apnea is diagnosed by regular, synchronous variations in heart rate, snoring, and oxygen saturation.

3. Method as in claim 1 further comprising diagnosing the severity of both obstructive sleep apnea and central apnea form the duration of periods of oxygen desaturation and the amount of oxygen desaturation in said periods.

4. Method as in claim 1 further comprising

sensing body position and generating a body position signal, and

storing said body position signal over time as one of said stored signals.

5. Method as in claim 4 wherein obstructive sleep apnea is diagnosed by regular, synchronous variations in heart rate, snoring, oxygen saturation, and body position.

6. Method as in claim 4 wherein said body position signal is compared to said other stored signals and a measure of unrest during sleep is also determined.

7. Method as in claim 1 wherein central apnea is diagnosed by regular, synchronous variations in heart rate and oxygen desaturation.

8. Method as in claim 1 wherein one of continuous snoring and upper airway resistance syndrome is diagnosed by a substantially continuous pattern of snoring signals without significant changes in oxygen saturation and with only irregular variations in heart rate.

9. Method as in claim 1 wherein said stored signals are further compared to indicate whether a further disorder consisting of one of polyneuropathy, arteriosclerosis, diabetes, and a threatened coronary infarction is present, said further disorder being indicated when oxygen desaturation is detected at a substantially constant heart rate.

10. Method as in claim 1 wherein the patient performs the additional step of marking time intervals with special events comprising lights out and waking up, which special events are stored over time as stored signals.

11. Method as in claim 1 wherein said loud breathing signal is generated for respiratory sounds having a first frequency range and generates said snoring signal for a second frequency range which is a lower part of said first frequency range.

21. Method as in claim 1 wherein the severity of both obstructive apnea and central apnea is determined from the duration and depth of periods of oxygen desaturation.

12. Apparatus for the ambulatory detection of physiological factors in a patient for use in diagnosing sleep disorders, comprising

means for sensing heart potentials and generating heat rate signals,

means for sensing respiratory sounds and generating a loud breathing signal and a snoring signal,

means for sensing degree of oxygen saturation in the patient'"'"'s blood and generating an oxygen saturation signal,

means for storing said heart rate signal, loud breathing signal, snoring signal, and oxygen saturation signal over time, and

means for comparing said stored signals to determine whether each one of obstructive sleep apnea, central apnea, continuous snoring, upper airway resistance syndrome, and nocturnal myoclonus is present.

13. Mobile apparatus as in claim 12 wherein said means for sensing degree of oxygen saturation comprises a light source and a light receiver for attachment to an extremity of the patient in facing relationship, said receiver generating a signal representing at least one of light absorption and reflection in said extremity.

14. Mobile apparatus as in claim 13 further comprising a U-shaped clip to which said light source and light receiver are fixed.

15. Mobile apparatus as in claim 12 further comprising means for detecting body position and generating a body position signal, said means for storing further storing said body position signal over time.

16. Mobile apparatus as in claim 15 wherein said means for detecting body position comprises a hollow member having electrical contacts therein and a conductive ball which bridges different contacts depending on the position of the patient.

17. Mobile apparatus as in claim 16 wherein said hollow member is a tetrahedron.

18. Mobile apparatus as in claim 12 wherein said means for sensing respiratory sounds generates said loud breathing signal for a first frequency range and generates said snoring signal for a second frequency range which is a lower part of said first frequency range.

19. Method for the ambulatory detection and diagnosis of sleep disorders in a patient, comprising

sensing heart potentials and providing a heart rate signal,

sensing respiratory signals and generating a loud breathing signal and a snoring signal,

sensing degree of oxygen saturation in the patient'"'"'s blood and generating an oxygen saturation signal,

sensing the patient'"'"'s body position and generating a body position signal,

storing said heart rate signal, loud breathing signal, snoring signal, oxygen saturation signal, and body position signal, and

comparing said stored signals to determine whether each one of obstructive apnea, central apnea and nocturnal myoclonus is present.

20. Method as in claim 19 wherein said stored signals are further compared to determine whether upper airway resistance syndrome is present.