Proteins and the preparation thereof

  • US 5,344,915 A
  • Filed: 09/26/1991
  • Issued: 09/06/1994
  • Est. Priority Date: 05/09/1989
  • Status: Expired due to Term
First Claim
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1. A purified and isolated TNFα

  • -binding protein which has a molecular weight of about 42,000 daltons and has at the N terminus the amino acid sequenceXaa Thr Pro Tyr Ala Pro Glu Pro Gly Set Thr Cys Arg Leu Arg Gluwhere Xaa is hydrogen, a phenylalanine residue (Phe) or the amino acid sequences Ala Phe, Val Ala Phe, Gln Val Ala Phe, Ala Gln Val Ala Phe, Pro Ala Gln Val Ala Phe or Leu Pro Ala Gln Val Ala Phe.

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