3,3-diphenylpropylamines and pharmaceutical compositions thereof

  • US 5,382,600 A
  • Filed: 12/19/1991
  • Issued: 01/17/1995
  • Est. Priority Date: 01/22/1988
  • Status: Expired due to Term
First Claim
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1. 3,3-Diphenylpropylamines of formula I ##STR31## wherein R1 signifies hydrogen or methyl, R2, R3 and R4 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphamoyl or halogen, and X represents a tertiary amino group of formula II ##STR32## wherein each of R5 and R6 independently signifies C1-6 alkyl, which may be joined to form a non-aromatic ring having no hetero atom other than the amine nitrogen and each of which may carry a hydroxy substituent, or adamantyl, and wherein R5 and R6 together contain at least four carbon atoms, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers.

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