Injection device
First Claim
1. A device for an injection apparatus, comprising:
- a dual-chamber injection cartridge, comprising;
a front end and a rear end;
a front opening in the vicinity of a front end of said cartridge;
a front chamber located in the vicinity of said front opening and including a drug freeze-dried in said front chamber,a rear chamber including a liquid component,a movable wall separating said front chamber and said rear chamber,a bypass for transferring said liquid component between said front chamber and said rear chamber, anda rear piston;
a cylindrical sleeve substantially the same length as said cartridge, said cartridge being slidably arranged within said sleeve;
a stopper located in the vicinity of said front opening of said cartridge, said stopper being directed rearwardly coaxially with said cartridge, wherein as said sleeve is displaced rearwardly after the freeze-drying of said drug said stopper enters the front opening of said cartridge to sealingly close said cartridge; and
means in the vicinity of said rear end of said cartridge for attaching means for actuating said rear piston.
2 Assignments
0 Petitions
Accused Products
Abstract
A device for an injection apparatus, including a dual-chamber injection cartridge. The cartridge includes a front end, a rear end, a front opening in the vicinity of a front end of the cartridge, a front chamber located in the vicinity of the front opening and including a drug freeze-dried in the front chamber, a rear chamber including a liquid component, a movable wall separating the front chamber and the rear chamber, a bypass for transferring the liquid component between the front chamber and the rear chamber, and a rear piston. The cartridge is slidably arranged within a cylindrical sleeve substantially the same length as the cartridge. A stopper is located in the vicinity of the front opening of the cartridge. The stopper is directed rearwardly coaxially with the cartridge, wherein as the sleeve is displaced rearwardly after the freeze-drying of the drug, the stopper enters the front opening of the cartridge to sealingly close the cartridge. An actuator for actuating the rear piston may be attached in the vicinity of the rear end of the cartridge.
102 Citations
17 Claims
-
1. A device for an injection apparatus, comprising:
-
a dual-chamber injection cartridge, comprising; a front end and a rear end; a front opening in the vicinity of a front end of said cartridge; a front chamber located in the vicinity of said front opening and including a drug freeze-dried in said front chamber, a rear chamber including a liquid component, a movable wall separating said front chamber and said rear chamber, a bypass for transferring said liquid component between said front chamber and said rear chamber, and a rear piston; a cylindrical sleeve substantially the same length as said cartridge, said cartridge being slidably arranged within said sleeve; a stopper located in the vicinity of said front opening of said cartridge, said stopper being directed rearwardly coaxially with said cartridge, wherein as said sleeve is displaced rearwardly after the freeze-drying of said drug said stopper enters the front opening of said cartridge to sealingly close said cartridge; and means in the vicinity of said rear end of said cartridge for attaching means for actuating said rear piston. - View Dependent Claims (3, 4, 5, 6, 7, 11, 12, 13, 14, 15, 16, 17)
-
-
2. A method for preparing an injection apparatus for dual-chamber injection cartridges, said method comprising the steps of:
-
providing a device for an injection apparatus, the device comprising a dual-chamber injection cartridge, including a front end, a rear end, a front chamber, a rear chamber, a movable wall separating the front chamber and the rear chamber, a bypass for transferring material between the front chamber and the rear chamber, and a piston; providing a solution or dispersion of a component in a front chamber of the cartridge; arranging a cylindrical sleeve around the cartridge; providing a front end of the sleeve with a stopper, said stopper being directed rearwardly toward and coaxially with the cartridge; inserting the cartridge into a freeze-drying apparatus; subjecting the solution or dispersion of the component to a freeze-drying process, the freeze-drying process being carried out with the stopper in a position where a front opening of the cartridge is not sealed; displacing the sleeve and the stopper rearwardly such that the stopper is inserted into the front opening of the cartridge to sealingly close to cartridge; removing the sealed cartridge from the freeze-drying apparatus; providing a liquid component in the rear chamber of the cartridge; and providing the rear end of the sleeve with means for actuating the rear piston. - View Dependent Claims (8, 10)
-
-
9. An injection apparatus, comprising:
-
a dual-chamber injection cartridge, comprising; a front end and a rear end; a front opening in the vicinity of a front end of said cartridge; a front chamber located in the vicinity of said front opening and including a drug freeze-dried in said front chamber, a rear chamber including a liquid component, a movable wall separating said front chamber and said rear chamber, a bypass for transfer,ring said liquid component between said front chamber and said rear chamber, and a rear piston; a cylindrical sleeve substantially the same length as said cartridge, said cartridge being slidably arranged within said sleeve; a stopper located in the vicinity of said front opening of said cartridge, said stopper being directed rearwardly coaxially with said cartridge, wherein as said sleeve is displaced rearwardly after the freeze-drying of said drug said stopper enters the front opening of said cartridge to sealingly close said cartridge; and means in the vicinity of said rear end of said cartridge for attaching means for actuating said rear piston.
-
Specification