Controlled release oxycodone compositions

  • US 5,508,042 A
  • Filed: 06/06/1995
  • Issued: 04/16/1996
  • Est. Priority Date: 11/27/1991
  • Status: Expired due to Term
First Claim
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1. A method for reducing the range in daily dosages required to control pain in human patients, comprising administering an oral controlled release dosage formulation comprising from about 10 to about 40 mg oxycodone or a salt thereof which provides a mean maximum plasma concentration of oxycodone from about 6 to about 60 ng/ml from a mean of about 2 to about 4.5 hours after administration, and a mean minimum plasma concentration from about 3 to about 30 ng/ml from a mean of about 10 to about 14 hours after repeated administration every 12 hours through steady-state conditions.

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