Implantable drug infusion system with safe bolus capability

• US 5,575,770 A
• Filed: 04/05/1995
• Issued: 11/19/1996
• Est. Priority Date: 04/05/1995
• Status: Expired due to Term

• Current Assignee: Therex Limited Partnership
• Original Assignee: Therex Corp. (Teleflex Incorporated)
• Inventors: Enegren, Bradley J., Melsky, Gerald S.
• Primary Examiner(s): Green, Randall L.
• Assistant Examiner(s): ELGART, VANITHA M
• Application Number:
  US08/417,240
• Time in Patent Office: 594 Days
• Field of Search: 604/86, 604/93, 604/131, 604/141, 604/891.1, 604/30, 604/132, 604/83-85, 604/236, 604/247, 604/151
• US Class Current: 604/288.04
• CPC Class Codes: A61M 5/14276 specially adapted for implantation

Abstract

An implantable infusion device includes a housing having opposite first and second walls and a relatively large blind passage extending into the housing from the first wall toward the second wall. A first self-sealing septum blocks the passage at the first wall and a second self-sealing septum blocks the passage at a location therein spaced from the first septum thereby defining an infusate chamber between the first and second septa and a blind chamber between the second septum and the housing second wall. A fluid pathway containing a normally closed valve extends from the infusate chamber to the exterior of the housing and a lever connected to the valve is located in the blind chamber. That lever may be depressed to open the valve only by a needle inserted through the two septa into the blind chamber which needle has a side opening aligned with the infusate chamber when such depression occurs.

Claims

1. An implantable infusion device comprising

a housing having a wall;

a first infusate chamber in the housing;

a first inlet port in said wall, said first inlet port communicating with said first chamber;

a first self-sealing septum closing said first inlet port at said wall;

an outlet catheter extending from said housing;

a first fluid pathway extending from said first chamber to said outlet catheter;

a second inlet port in said wall, said second inlet port extending into the interior of said housing;

a second self-sealing septum closing said second inlet port at said wall;

a third self-sealing septum positioned in the second inlet port and spaced from said second septum therein so as to define between said second and third septa a second infusate chamber in the housing;

a second fluid pathway extending from the second chamber to said outlet catheter;

a valve in said second fluid pathway, said valve being movable between open and closed positions to open and close the second fluid pathway;

means for biasing the valve to its closed position, and

valve actuating means located in the second inlet port on the opposite side of the third septum from the second chamber, said actuating means being adapted to open said valve only when contacted by a needle that penetrates through both the second and third septa.

2. The device defined in claim 1 wherein

a segment of the second inlet port extends away from said wall beyond the third septum to form a closed chamber within the housing;

said valve has a portion which extends into said closed chamber, and

the valve actuating means comprise a lever pivotally mounted in said closed chamber and connected to said valve portion.

3. The device defined in claim 2 and further including means positioned in the housing between the third septum and the closed chamber for preventing the third septum from deflecting into the closed chamber.

4. The device defined in claim 2 wherein the closed chamber is filled with an incompressible liquid.

5. An implantable infusion device comprising

a housing having opposite first and second walls;

a relatively large blind passage extending into the housing from the first wall toward the second wall;

a first self-sealing septum blocking the passage at the first wall;

a second self-sealing septum blocking the passage at a location therein spaced from the first septum thereby defining an infusate chamber between the first and second septa and a blind chamber between the second septum and the housing second wall;

a fluid pathway extending from the infusate chamber to the exterior of the housing;

a valve in said fluid pathway, said valve being movable between open and closed positions to open and close the fluid pathway;

a lever having a portion connected to said valve and being pivotally mounted in said blind chamber so that the lever is movable in said blind chamber between a raised position relatively close to the second septum wherein the valve is closed and a depressed position relatively close to the housing second wall wherein said valve is open, and

means for biasing the lever to its raised position wherein said valve remains closed unless said lever is depressed by a needle penetrating said blind chamber.

6. The device defined in claim 5 wherein said blind chamber is filled with an incompressible liquid.

7. The device defined in claim 5 wherein said biasing means comprise a coil spring compressed between said lever and the housing second wall.

8. The device defined in claim 5 and further including a hollow needle having a closed pointed tip and a side opening spaced from said tip a distance approximately equal to the distance between said infusate chamber and the housing second wall so that when said needle is inserted through the first and second septa into said blind chamber sufficient to move the lever to its depressed position, the needle side opening is aligned with the infusate chamber.

9. The device defined in claim 8 wherein said needle side opening is elongated.

10. The device according to claim 5 and further including

an infusate reservoir in the housing;

an inlet port extending from the housing first wall to said reservoir;

an additional self-sealing septum blocking the inlet port at said first wall, and

a fluid conduit extending from said reservoir to said fluid pathway downstream from said valve.

11. The device defined in claim 10 wherein said infusate reservoir is a pumpable reservoir.

12. The device defined in claim 10 and further including a flexible outlet catheter having one end connected to said housing and being in fluid communication with said fluid pathway.