Antimicrobial complexes

• US 5,576,006 A
• Filed: 09/23/1994
• Issued: 11/19/1996
• Est. Priority Date: 08/14/1991
• Status: Expired due to Fees

• Current Assignee: W Novis Smith and Company
• Original Assignee: W Novis Smith and Company
• Inventors: Smith, W. Novis
• Primary Examiner(s): Kishore, Gollamudi S.
• Application Number:
  US08/311,151
• Time in Patent Office: 788 Days
• Field of Search: 424/404, 424/43, 424/46, 424/489, 424/76.2, 424/76.8, 36/36, 36/43, 36/44, 36/98, 523/122
• US Class Current: 424/404
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/10 Macromolecular compounds
• CPC Class Codes: A01N 33/12 Quaternary ammonium compounds
• CPC Class Codes: A01N 37/04 polybasic
• CPC Class Codes: A01N 37/06 Unsaturated carboxylic acids or thio analogues thereof; Derivatives thereof
• CPC Class Codes: A01N 37/36 containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
• CPC Class Codes: A01N 43/64 having rings with three nitrogen atoms as the only ring hetero atoms
• CPC Class Codes: A01N 43/90 having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
• CPC Class Codes: A01N 47/44 Guanidine; Derivatives thereof
• CPC Class Codes: A61K 2800/5424 anionic
• CPC Class Codes: A61K 8/362 Polycarboxylic acids
• CPC Class Codes: A61K 8/416 Quaternary ammonium compounds A61K8/35 takes precedence
• CPC Class Codes: A61K 8/43 Guanidines
• CPC Class Codes: A61K 8/494 with more than one nitrogen as the only hetero atom
• CPC Class Codes: A61K 8/4966 Triazines or their condensed derivatives
• CPC Class Codes: A61K 8/731 Cellulose; Quaternized cellulose derivatives
• CPC Class Codes: A61K 8/8152 Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
• CPC Class Codes: A61Q 1/02 Preparations containing skin colorants, e.g. pigments preparations in powder form A61Q1/12
• CPC Class Codes: A61Q 1/12 Face or body powders for grooming, adorning or absorbing
• CPC Class Codes: A61Q 15/00 Anti-perspirants or body deodorants deodorisation of air A61L9/00
• CPC Class Codes: A61Q 17/005 : Antimicrobial preparations
• CPC Class Codes: A61Q 3/00 : Manicure or pedicure preparations

Abstract

There is provided complexes of antifungal or antimicrobial compounds having at least one site which is a quaternary ammonium, amine, a mixture thereof, or the salts thereof. The complexes are useful in compositions for deodorizing and/or preventing the growth of odor causing microbes or fungus. The compositions are particularly useful for deodorizing footwear.

Claims

1. A method for deodorizing or reducing odors in footwear which comprises treating footwear with a composition in the form of a spray comprising an antifungal, biocidal or antimicrobial film forming complex of a polycarboxylic acid and a functional antimicrobial, biocidal or antifungal compound having at least one site which is quaternary ammonium, amine, a mixture thereof or the salts thereof, said film forming complex being the reaction product of said functional compound and a polycarboxylic acid wherein at least two functional molecules complex or coordinate per molecule of polycarboxylic acid.

4. The method of claim 1 wherein said antimicrobial compound is a triazine.

5. The method of claim 4 wherein said triazine is 1, 3, 5-tris (2-hydroxylethyl) hexahydro-5-triazine.

6. The method of claim 1 wherein said antimicrobial agent is a tetramine.

7. The method of claim 6 wherein said tetramine is 1, 3, 5, 7-tetra-aza-adamantane hexamethylenetetramine.

8. The method of claim 6 wherein said tetramine is 1-(3-chloroallyl) -3, 5, 7-triaza-1-azonia adamantane.

2. A method for deodorizing or reducing odors in footwear which comprises treating footwear with a composition comprising an effective amount of a film forming complex of a polycarboxylic acid and a functional antimicrobial, biocidal or antifungal biguanide compound or the salts thereof, said film forming complex being the reaction product of said functional compound and a polycarboxylic acid wherein at least two functional molecules complex or coordinate per molecule of polycarboxylic acid.

3. The method of claim 2 wherein said biguanide is a polyhexamethylene biguanide hydrochloride.

9. The method of claim 2 wherein said complex is a complex of a polycarboxylic acid having 2-4 carbon atoms and an antimicrobial compound which is a biguanide.

10. The method of claim 9 wherein said polycarboxylic acid is citric acid and said biguanide is polyhexamethylene biguanide acid addition salt.

11. The method of claim 2 wherein said composition includes an odor absorbent.

12. The method of claim 11 wherein said odor absorbent is ammonium carbonate or ammonium bicarbonate.

13. The method of claim 2 wherein said composition includes a perfume.