Crystalline amifostine compositions

  • US 5,591,731 A
  • Filed: 02/16/1995
  • Issued: 01/07/1997
  • Est. Priority Date: 07/31/1992
  • Status: Expired due to Term
First Claim
Patent Images

1. A dosage form of crystalline amifostine comprising thermally-stable, sterile, crystalline amifostine trihydrate exhibiting substantially the crystal structure having a space group of P21 21 21 and cell dimensions of about a=8.46 Å

  • , b=21.55 Å and

    c=6.76 Å

    , which is suitable for reconstitution with a pharmaceutically acceptable vehicle into an injectable particulate-free drug product for parenteral administration to a subject.

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