Pen-shaped syringe

• US 5,611,783 A
• Filed: 05/20/1994
• Issued: 03/18/1997
• Est. Priority Date: 11/29/1991
• Status: Expired due to Fees

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Mikkelsen, S.o slashed.ren
• Primary Examiner(s): McDermott, Corrine M.
• Assistant Examiner(s): STRIGHT, RONALD K
• Application Number:
  US08/256,888
• Time in Patent Office: 1,033 Days
• Field of Search: 604/208-211, 604/220, 604/201, 604/71, 604/72, 604/135, 604/136, 604/224, 604/218, 604/287, 604/232, 604/207
• US Class Current: 604/208
• CPC Class Codes: A61M 2005/2488 via rotation, e.g. threads or bayonet
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/3129 Syringe barrels A61M5/3205 and A61M5/50 take precedence
• CPC Class Codes: A61M 5/315 Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
• CPC Class Codes: A61M 5/31553 without axial movement of dose setting member
• CPC Class Codes: A61M 5/31591 Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion
• CPC Class Codes: A61M 5/5013 Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
• CPC Class Codes: A61M 5/502 for blocking the piston

Abstract

A pen-shaped syringe comprises a first part containing a dose setting and driving mechanism from which a piston rod is advanced by a carrier to actuate a piston of a reservoir in a second part. The first and second parts are coupled together by a bayonet coupling, wherein the bayonet coupling element of the second part has members for rotating a piston rod guide mounted on the bayonet coupling element of the first part. The piston rod determines the rotational position of the piston rod which rotational position again determines the engagement between the carrier and the piston rod.

Claims

1. An apparatus for use with a pen shaped syringe comprising a first part having an end surface carrying a tubular stud with a flange forming a bayonet coupling part, and a second part having interlocking bayonet coupling means for engagement with the bayonet coupling part of the first part, the first part further comprising:

(a) a piston rod projecting through the stud and having a non-circular cross section and carrying along one side a cogging,

(b) a carrier on a proximal end of the piston rod which can be advanced to inject a set dose of medicine and which unidirectionally transmits axial movements of this carrier to the piston rod,

(c) a piston rod guide mounted on the stud at an end of the flange, said piston rod guide maintaining the piston rod in a rotational position in the syringe ensuring the engagement between the carrier and the cogging of the piston rod when the syringe is in use, the piston rod guide having a non circular opening conforming to the cross section of the piston rod, and through which opening the piston rod passes,

said second part being tubular and having an open proximal and a distal end, said interlocking bayonet coupling means being on said proximal end thereof, the second part further comprising;

(a) a tubular reservoir for medicine, located within said second part which reservoir has a first end placed at the distal end of the second part, and a second end placed at the proximal end of the second part and closed by a piston which can be actuated by the piston rod,

wherein the interlocking bayonet coupling means of the second part is provided with means engaging the piston rod guide to rotate this guide and consequently the piston rod during at least part of a rotational movement of the bayonet coupling means in relation to the stud, the flange having an outer diameter corresponding to an inner diameter at the proximal end of the tubular second part, such that a space is left between the flange and the end surface of the first part, the flange being cut away preferably at diametrically opposite positions, and locking protrusions on an inner surface of the proximal end of the first part corresponds to the cut of the flange and extend axially from the proximal end a distance way from this proximal end, which distance corresponds to the distance between the flange and the end surface of the first part.

2. An apparatus according to claim 1, wherein the piston rod guide has the shape of a piston rod guide disk, which has a diameter corresponding to the diameter of the flange, and which piston rod guide disk has cuts at least corresponding to the cuts of the flange, the flange and the piston rod guide disk being provided with engaging stop means limiting the rotational movement of the piston rod guide disk, and an inner surface of the second part is provided with a protrusion engaging a cut in the piston rod guide disk, which protrusion lies at a distance from the proximal end of the second part corresponding to the length of the stud.

3. An apparatus according to claim 2, wherein the second part of the syringe further comprises an integral pawl mechanism for engagement with the cogging of the piston rod, and the cut in the piston rod guide disk extends over 90 degrees of the perimeter of said piston rod guide disk and is engaged by the protrusion on the inner surface of the second part of the syringe.

4. An apparatus according to claim 1, wherein the flange is provided with a set of cuts, a first cut forming a slot through the flange and a pair of second cuts at a position principally diametrically opposite the first cut but provided on both sides of a position exactly diametrically opposite the first cut.

5. An apparatus according to claim 1, wherein the piston rod has a square cross section and is provided with coggings along two opposite sides and is smooth along two other opposite sides.