Intron sequence analysis method for detection of adjacent and remote locus alleles as haplotypes

  • US 5,612,179 A
  • Filed: 09/23/1992
  • Issued: 03/18/1997
  • Est. Priority Date: 08/25/1989
  • Status: Expired due to Term
First Claim
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1. A method for detection of at least one coding region allele of a multi-allelic genetic locus comprising:

  • a) amplifying genomic DNA with a primer pair that spans a non-coding region sequence, said primer pair defining a DNA sequence which is in genetic linkage with said genetic locus and contains a sufficient number of non-coding region sequence nucleotides to produce an amplified DNA sequence characteristic of said allele; and

    b) analyzing the amplified DNA sequence to detect the allele.

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