Method and apparatus for alleviating cardioversion shock pain

• US 5,662,689 A
• Filed: 09/08/1995
• Issued: 09/02/1997
• Est. Priority Date: 09/08/1995
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Otten, Lynn M., Mehra, Rahul, Rise, Mark T., Thompson, David L., Elsberry, Dennis D.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): LAYNO, CARL HERNANDZ
• Application Number:
  US08/525,995
• Time in Patent Office: 725 Days
• Field of Search: 607/4, 607/5, 607/7, 607/8, 607/46
• US Class Current: 607/5
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/3962 in combination with another heart therapy
• CPC Class Codes: A61N 1/39622 Pacing therapy
• CPC Class Codes: A61N 1/39624 Pain reduction therapy

Abstract

An implantable cardioverter for providing cardioversion electrical energy to at least one chamber of a patient'"'"'s heart in need of cardioversion and applying a pain alleviating therapy at an appropriate site in the patient'"'"'s body prior to or in conjunction with the delivery of the cardioversion energy to the heart chamber to alleviate propagated pain perceived by the patient. The combined cardioversion and pain alleviating therapies are preferably realized in a single implantable, multi-programmable medical device or separate implantable cardioversion and pain control devices with means for communicating operating and status commands between the devices through the patient'"'"'s body.

Claims

1. An implantable medical device system for delivering cardioversion energy to at least one chamber of a patient'"'"'s heart in need of cardioversion and for alleviating pain attendant to delivery of cardioversion energy comprising:

detecting means for detecting activity of a chamber of the patient'"'"'s heart;

determining means responsive to the detecting means for determining when the chamber of the patient'"'"'s heart is in need of cardioversion;

cardioverting means responsive to the determining means for delivering cardioversion energy to the chamber of the patient'"'"'s heart when the chamber is in need of cardioversion; and

means for delivering neurostimulation pulses to the patient'"'"'s nervous system to effect analgesia at an appropriate site in the patient'"'"'s body in conjunction with delivery of cardioversion energy to the heart chamber to reduce pain felt by the patient arising from delivery of the cardioversion energy.

2. The system of claim 1 wherein the pain alleviating therapy applying means comprises means for delivering neurostimulation pulses to the patient in the region of spinal segments T1 through T4.

49. The system of claim 1 or claim 10 wherein the pain alleviating therapy applying means comprises means for delivering a sleep inducing agent to the patient to render the patient unconscious during deliver of the cardioversion energy.

50. The system of claim 49 further comprising:

means delaying delivery of cardioversion energy from the delivery of the sleep inducing agent to allow the patient to become unconscious prior to delivery of the cardioversion energy.

51. The system of claim 1 or claim 10 wherein the pain alleviating therapy applying means comprises means for delivering a threshold reducing agent to the patient to allow reduction of the cardioversion energy delivered to the patient.

52. The system of claim 51 further comprising:

means delaying delivery of cardioversion energy from the application of the threshold reducing agent to allow for reduction in the cardioversion threshold of the patient prior to delivery of the cardioversion energy.

3. An implantable medical device system for delivering cardioversion energy to at least one chamber of a patient'"'"'s heart in need of cardioversion and for alleviating pain attendant to delivery of cardioversion energy comprising:

detecting means for detecting activity of a chamber of the patient'"'"'s heart;

determining means responsive to the detecting means for determining when the chamber of the patient'"'"'s heart is in need of cardioversion;

cardioverting means responsive to the determining means for delivering cardioversion energy to the chamber of the patient'"'"'s heart when the chamber is in need of cardioversion; and

means for applying a pain alleviating therapy at an appropriate site in the patient'"'"'s body in conjunction with delivery of cardioversion energy to the heart chamber to reduce pain felt by the patient during delivery of the cardioversion energy; and

wherein the pain alleviating therapy applying means comprises means for delivering neurostimulation pulses to the patient'"'"'s nervous system to effect analgesia,

means for timing delivery of cardioversion energy from the application of the pain alleviating therapy to allow time dependent effects of the applied pain alleviating therapy to take effect.

4. The system of claim 3 wherein the pain alleviating therapy applying means comprises means for delivering the analgesic to the patient'"'"'s heart.

5. The system of claim 3 wherein:

said cardioverting means further comprises at least one cardioverting lead having a cardioverting electrode placed in contact with the patient'"'"'s heart; and

said pain alleviating therapy applying means comprises means for delivering the analgesic to the patient'"'"'s heart through the cardioverting electrode.

6. The system of claim 3 wherein the pain alleviating therapy applying means comprises means for delivering a bolus of an analgesic to the patient'"'"'s body to effect analgesia.

7. The system of claim 6 wherein the pain alleviating therapy applying means comprises means for delivering the analgesic to the patient in the region of spinal segments T1 through T4.

8. The system of claim 3 wherein the pain alleviating therapy applying means comprises means for delivering neurostimulation pulses to the patient'"'"'s nervous system to effect analgesia.

9. The system of claims 8 wherein the pain alleviating therapy applying means comprises means for delivering neurostimulation pulses to the patient in the region of spinal segments T1 through T4.

10. An implantable medical device for delivering cardioversion energy to the atria of a patient'"'"'s heart in need of atrial cardioversion and for alleviating pain attendant to the delivery of the atrial cardioversion energy comprising:

detecting means for detecting electrical activity of the atria of the patient'"'"'s heart;

determining means responsive to the detecting means for determining when the atria are in need of cardioversion;

implantable atrial cardioversion means for delivering atrial cardioversion shocks to the patient'"'"'s atria in need of cardioversion; and

implantable pain alleviating means for applying a pain alleviating therapy to the patient'"'"'s body in conjunction with delivery of atrial cardioversion shocks to reduce pain felt by the patient.

11. The system of claim 10 further comprising:

delay means responsive to the determination of atrial fibrillation for delaying delivery of the atrial cardioversion shock for a time period sufficient to allow the pain alleviating therapy to become effective.

12. The system of claim 11 wherein the pain alleviating therapy applying means comprises means for delivering a bolus of an analgesic to the patient'"'"'s body to effect analgesia.

13. The system of claim 12 wherein the pain alleviating therapy applying means comprises means for delivering the analgesic to the patient in the region of spinal segments T1 through T4.

14. The system of claim 10 wherein the pain alleviating therapy applying means comprises means for delivering neurostimulation pulses to the patient'"'"'s body to effect analgesia.

15. The system of claim 14 wherein the pain alleviating therapy applying means comprises means for delivering neurostimulation pulses to the patient in the region of spinal segments T1 through T4.

16. The system of claim 10 wherein the pain alleviating therapy applying means comprises means for delivering a bolus of the analgesic to the patient'"'"'s body to effect analgesia.

17. The system of claim 16 wherein the pain alleviating therapy applying means comprises means for delivering the analgesic to the patient in the region of spinal segments T1 through T4.

18. The system of claim 10 further comprising:

means for detecting a depolarization of the ventricles of the patient'"'"'s heart;

means for timing a synchronization period from the detection of a ventricular depolarization;

means for delivering the atrial cardioversion shock in the synchronization period.

19. The system of claim 18 further comprising:

delay means responsive to the determination of atrial fibrillation for delaying delivery of the atrial cardioversion shock for a delay time period sufficient to allow the applied pain alleviating therapy to become effective.

20. The system of claim 18 further comprising:

re-verification means for re-verifying the continuation of the determination of atrial fibrillation at the end of the delay time period.

21. The system of claim 10 wherein the pain alleviating therapy applying means comprises means for delivering an analgesic to the patient'"'"'s heart.

22. The system of claim 10 wherein:

said cardioverting mean further comprises at least one cardioverting lead having a cardioverting electrode placed in contact with the patient'"'"'s heart; and

said pain alleviating therapy applying means comprises means for delivering an analgesic to the patient'"'"'s heart through said cardioverting electrode.

23. The system of claim 10 wherein:

said pain alleviating therapy applying means comprises means for delivering neurostimulation pulses and a bolus of the analgesic to the patient'"'"'s body to effect analgesia.

24. The system of claim 23 wherein the pain alleviating therapy applying means comprises:

means for delivering neurostimulation pulses to the patient in the region of spinal segments T1 through T4; and

means for delivering the analgesic to the patient in the region of spinal segments T1 through T4.

25. A method of delivering cardioversion energy to at least one chamber of a patient'"'"'s heart in need of cardioversion comprising the steps of:

detecting activity of the at least one chamber of the patient'"'"'s heart;

determining from the detected activity when the at least one chamber of the patient'"'"'s heart is in need of cardioversion;

delivering neurostimulation pulses to the patient'"'"'s nervous system to effect analgesia to alleviate pain in body tissue arising from the delivery of the cardioversion energy; and

delivering cardioversion energy to the at least one chamber of the patient'"'"'s heart.

26. The method of claim 25 wherein the step of applying the pain alleviating therapy applying comprises delivering neurostimulation pulses to the patient in the region of spinal segments T1 through T4.

53. The method of claim 25 or claim 34 wherein the step of applying the pain alleviating therapy comprises delivering a sleep inducing agent to the patient to render the patient unconscious during delivery of the cardioversion energy.

54. The method of claim 53 further comprising the steps of delaying of the cardioversion energy from the delivery of the sleep inducing agent to allow the patient to become conscious prior to delivery of the cardioversion energy.

55. The method of claim 25 or claim 34 wherein the step of applying the pain alleviating therapy comprises delivering a threshold reducing agent to the patient to allow reduction of the cardioversion energy delivered to the patient.

56. The method of claim 55 further comprising the step of delaying delivery of cardioversion energy from the application of the threshold reducing agent to allow for reduction in the cardioversion threshold of the patient prior to delivery of the cardioversion energy.

27. A method of delivering cardioversion energy to at least one chamber of a patient'"'"'s heart in need of cardioversion comprising the steps of:

detecting activity of the at least one chamber of the patient'"'"'s heart;

determining from the detected activity when the at least one chamber of the patient'"'"'s heart is in need of cardioversion;

applying a pain alleviating therapy to a site in the patient'"'"'s body to alleviate pain in body tissue arising from the delivery of the cardioversion energy; and

delivering cardioversion energy to the at least one chamber of the patient'"'"'s heart; and

timing the delivery of the cardioversion energy from the application of the pain alleviating therapy sufficiently to allow time dependent analgesia effects of the applied pain alleviating therapy to take effect.

28. The method of claim 27 wherein the step of applying the pain alleviating therapy comprises delivering the analgesic to the patient'"'"'s heart.

29. The method of claim 27 wherein:

the step of delivering cardioversion energy comprises placing at least one cardioverting lead having a cardioverting electrode in contact with the patient'"'"'s heart; and

wherein the step of applying the pain alleviating therapy comprises delivering the analgesic to the patient'"'"'s heart through said cardioverting electrode.

30. The method of claim 27 wherein the step of applying the pain alleviating therapy comprises delivering a bolus of analgesic to the patient'"'"'s body to effect analgesia.

31. The method of claim 30 wherein the step of applying the pain alleviating therapy comprises delivering the analgesic to the patient in the region of spinal segments T1 through T4.

32. The method of claim 27 wherein the step of applying the pain alleviating therapy comprises delivering neurostimulation pulses to the patient'"'"'s nervous method to effect analgesia.

33. The method of claim 32 wherein the step of applying the pain alleviating therapy comprises delivering the neurostimulation pulses to the patient in the region of spinal segments T1 through T4.

34. A method of providing cardioversion energy to the atria of a patient'"'"'s heart in need of atrial cardioversion and for alleviating pain attendant to the delivery of the atrial cardioversion energy comprising the steps of:

detecting electrical activity of the atria of the patient'"'"'s heart;

in response to the detecting step, determining when the atria are in need of cardioversion;

delivering atrial cardioversion shocks to the patient'"'"'s atria in need of cardioversion; and

applying a pain alleviating therapy to the patient'"'"'s body in conjunction with the delivery of the atrial cardioversion shocks to reduce pain felt by the patient.

35. The method of claim 34 further comprising the step of:

in response to the determination of atrial fibrillation, delaying the delivery of the atrial cardioversion shock for a time period sufficient to allow the applied pain alleviating therapy to become effective.

36. The method of claim 35 wherein the step of applying the pain alleviating therapy comprises delivering a bolus of analgesic to the patient'"'"'s body to effect analgesia.

37. The method of claim 36 wherein the step of applying the pain alleviating therapy comprises delivering the analgesic to the patient in the region of spinal segments T1 through T4.

38. The method of claim 34 wherein the step of delivering pain alleviating therapy comprises delivering neurostimulation pulses to the patient'"'"'s body to effect analgesia.

39. The method of claim 38 wherein the step of applying the pain alleviating therapy comprises delivering neurostimulation pulses to the patient in the region of spinal segments T1 through T4.

40. The method of claim 34 wherein the step of applying the pain alleviating therapy comprises delivering a bolus of analgesic to the patient'"'"'s body to effect analgesia.

41. The method of claim 40 wherein the step of applying the pain alleviating therapy comprises delivering the analgesic to the patient in the region of spinal segments T1 through T4.

42. The method of claim 34 further comprising the step of:

in response to the determination of atrial fibrillation, delaying delivery of the atrial cardioversion shock for a delay time period sufficient to allow the applied pain alleviating therapy to become effective.

43. The method of claim 42 further comprising the steps of:

detecting a depolarization of the ventricles of the patient'"'"'s heart;

timing a synchronization period from the detection of a ventricular depolarization;

delivering the atrial cardioversion shock in the synchronization period.

44. The method of claim 42 further comprising the steps of:

re-verifying the continuation of the determination of atrial fibrillation at the end of the delay time period;

detecting a depolarization of the ventricles of the patient'"'"'s heart;

timing a synchronization period from the detection of a ventricular depolarization;

delivering the atrial cardioversion shock in the synchronization period.

45. The method of claim 34 wherein the step of delivering the pain alleviating therapy comprises delivering an analgesic to the patient'"'"'s heart.

46. The method of claim 34 wherein:

the step of delivering the atrial cardioversion shock comprises placing at least one cardioverting lead having a cardioverting electrode in contact with the patient'"'"'s heart; and

wherein the step of applying the pain alleviating therapy comprises delivering an analgesic to the patient'"'"'s heart through said cardioverting electrode.

47. The method of claim 34 wherein:

the step of applying the pain alleviating therapy comprises delivering neurostimulation pulses and a bolus of an analgesic to the patient'"'"'s body to effect analgesia.

48. The method of claim 47 wherein the step of applying the pain alleviating therapy comprises:

delivering neurostimulation pulses to the patient in the region of spinal segments T1 through T4; and

delivering the analgesic to the patient in the region of spinal segments T1 through T4.