Apparatus and methods for communications with implanted active medical devices

• US 5,674,265 A
• Filed: 12/23/1994
• Issued: 10/07/1997
• Est. Priority Date: 12/31/1993
• Status: Expired due to Term

• Current Assignee: Sorin CRM USA (MicroPort Scientific Corp.)
• Original Assignee: Ela Medical S.A. (LivaNova Plc)
• Inventors: Lee, Chikyam, Deschamps, Herve
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US08/363,742
• Time in Patent Office: 1,019 Days
• Field of Search: 607/9, 607/30-32, 607/52, 607/59, 607/60, 128/696, 128/697, 128/901-903, 128/653.1, 364/413.26, 455/137, 455/138, 455/234.1, 455/246.1, 455/296, 340/870.04, 340/870.05, 340/870.41
• US Class Current: 607/60
• CPC Class Codes: A61N 1/37223 Circuits for electromagnetic coupling
• CPC Class Codes: H04R 25/606 acting directly on the eardrum, the ossicles or the skull, e.g. mastoid, tooth, maxillary or mandibular bone, or mechanically stimulating the cochlea, e.g. at the oval window
• CPC Class Codes: Y10S 128/901 Suppression of noise in electric signal
• CPC Class Codes: Y10S 128/903 Radio telemetry

Abstract

Process and apparatus for extracting a useful signal emitted by an implanted active medical device in the presence of parasitic signals. This device includes a plurality of signal receivers located at distinct points. The signal receivers are sensitive to the magnetic component of the electromagnetic signals and separated from each other by a distance that is negligible as compared to the wavelength of the electromagnetic signal. A plurality of amplifiers are provided with one amplifier being associated with each signal receiver and each amplifier having an adjustable gain. The amplified signals are summed by an adder, and the summed signal (V(t)) is evaluated using a magnitude (|V|) representative of the level of the summed signal. A processing means is used in the absence of the useful signal to adjust the gain of each amplifier, as appropriate, to minimize the magnitude in a preliminary step, and to maintain the amplifier gains at the adjusted values in a subsequent step, in the presence of the useful signal. As a result, the useful signal is acquired and the perturbing signals are suppressed.

Claims

1. A device to extract a useful signal, emitted by an implanted medical apparatus, in an electromagnetic signal having a wavelength and including the useful signal mixed with a parasitic signal, comprising:

a plurality of signal receivers located at distinct points and spaced apart relative to each other by a distance of separation, the distance of separation between said signal receivers being negligible relative to the wavelength of the electromagnetic signal, each signal receiver being sensitive to the magnetic component of the electromagnetic signal;

a plurality of amplifiers, each one of said plurality of amplifiers being coupled to one of the plurality of signal receivers and having an input, an adjustable gain, and an amplified output;

means for summing the amplified outputs and providing a consequent sum signal output;

means for evaluating a magnitude representative of the level of the consequent summed signal, and

means for processing said magnitude and adjusting the gains of said plurality of amplifiers to minimize the magnitude in a preliminary step in the absence of the useful signal, and to maintain said amplifiers at said adjusted gains in a second step in the presence of the useful signal.

2. The device of claim 1, in which the plurality of signal receivers comprises a first signal receiver and a second signal receiver.

3. The device of claim 1, wherein the processing means provides the representative magnitude as one of an absolute value of the consequent sum signal and an efficient value of the consequent sum signal.

4. The device of claim 1, in which the processing means further comprises a linear calculation means for solving a system of linear equations, each equation in the system having an unknown, in which said amplifier gains are the unknowns.

5. A process to extract a useful signal, emitted by an implanted medical apparatus, in an electromagnetic signal having a wavelength including the useful signal mixed with a parasitic signal, including the steps of:

a) conducting a preliminary step of;

(i) inhibiting the emission of the useful signal by the implanted apparatus;

(ii) receiving the parasitic signal by a plurality of signal receivers located at different positions and spaced a distance apart relative to each other, each signal receiver including an associated amplifier having an adjustable gain and an amplified output and being sensitive to the magnetic component of the electromagnetic signal, the distance separating the signal receivers being negligible as compared to the wavelength of the electromagnetic signal;

(iii) summing the amplified outputs delivered by the amplifiers and providing a sum signal output;

(iv) evaluating the magnitude of the sum signal; and

(v) adjusting the gain of each amplifier to the extent necessary to provide a minimum sum signal; and

(b) conducting a subsequent step of;

(i) causing the implanted device to emit the useful signal,

(ii) collecting at the plurality of signal receivers the electromagnetic signal including the useful signal and the parasitic signal, and

(iii) maintaining the values of the gains of the amplifiers at the values adjusted in the preliminary step (a) (v).

6. The process of claim 5, further comprising repeating steps (a) and (b) sequentially so that the gains of amplifiers are re-evaluated and readjusted, if necessary, on each execution of step (a).

7. The process of claim 5, in which the step of adjusting the gain in step (a) (v) comprises:

establishing a linear system of P equations including P+1 unknowns, wherein the unknowns are said amplifier gains, and the coefficients are the coefficients of coupling between fields and antennae;

fixing arbitrarily the value of one gain; and

deducing the P other values of gain relative to the fixed gain.

8. The method of claim 7 further comprising repeating steps (a) and (b) sequentially so that the gains of the amplifiers are re-evaluated and readjusted on each execution of step (a).

9. The method of claim 8 wherein on each repetition of step (a), the amplifier gain value arbitrarily selected is of a different amplifier than the amplifier selected on the preceding execution of step (a), and the other amplifier gain values are deduced relative to said one arbitrarily selected gain value.

10. The method of claim 8 wherein on each repetition of step (a), the amplifier gain value arbitrarily selected is a different gain value than the gain value selected on the preceding execution of step (a), and the other amplifier gain values are deduced relative to said one arbitrarily selected gain value.

11. An apparatus for separating a useful signal emitted by an implanted active medical device from an electromagnetic signal having a wavelength and including the useful signal and perturbing signals, comprising:

a first plurality of signal receivers, said signal receivers being spaced apart relative to each other a distance that is negligible with respect to the electromagnetic signal wavelength, each receiver having a coil sensing a magnetic field component of the electromagnetic field and an output signal corresponding to the sensed magnetic field component;

a second plurality of amplifiers associated with said first plurality of signal receivers so that each signal receiver is coupled to an amplifier, each amplifier having an input receiving a coil output signal, an adjustable gain, and an amplified output;

an adder circuit summing the amplified outputs of said second plurality of amplifiers and having a sum signal output;

means for processing said sum signal and controlling the plurality of amplifier gains in one of a first operating mode in the absence of said useful signal, to select the gains of said plurality of amplifiers to minimize the magnitude of said sum signal, and a second operating mode in the presence of said useful signal, to maintain the amplifier gains as selected in said first operating mode, thereby to obtain a sum signal representative of the useful signal in the second operating mode.

12. The apparatus of claim 11 wherein the first plurality of receiver signal coils further comprise a first coil and a second coil, and wherein the second plurality of amplifiers further comprises a first amplifier and a second amplifier, the first and second amplifiers being connected to amplify the first and second coil output signals, respectively.

13. The apparatus of claim 11 wherein said processing means in said first operating mode further comprises:

means for receiving said sum signal and providing a second signal representative of the sum signal; and

first means for selecting arbitrarily a first value of one of said plurality of amplifier gains and second means for selecting a value of each of the other of said plurality of amplifier gains to minimize the second signal.

14. The apparatus of claim 13 wherein the second signal comprises one of an absolute value of the sum signal and an efficient value of the sum signal.

15. The apparatus of claim 14 wherein the second selecting means operates to select one of said other amplifier gain values at a time in a predetermined sequence.

16. The apparatus of claim 13 wherein the first and second selecting means further comprise a set of linear equations in which the amplifier gain values are the unknowns, and a calculation module processing said equation set to solve the unknowns.

17. An apparatus for receiving useful telemetry signals emitted at a first wavelength by an implanted active medical device in the presence of perturbing noise, comprising:

a first receiver coil having a first coil output signal that is responsive to the magnetic field component of an electromagnetic signal at said first wavelength;

a first amplifier having an input coupled to the first coil output signal, an adjustable gain, and an amplified output;

a second receiver coil having a second coil output signal that is responsive to the magnetic field component of said electromagnetic signal at said first wavelength;

a second amplifier having an input coupled to the second coil output signal, an adjustable gain, and an amplified output;

an adder circuit having as inputs said first and second amplifier outputs and having an output corresponding to the sum of the first and second amplifier outputs;

a circuit having an input receiving the adder circuit output and an output signal that is a magnitude representative of the magnitude of the adder circuit output; and

means for processing said magnitude in a first operation in the absence of the useful telemetry signal to adjust the gains of the first and second amplifiers to first and second gain values, respectively, to minimize the magnitude, and in a second operation in the presence of the useful telemetry signal to acquire the useful telemetry signal based on said adjusted first and second amplifier gains suppressing said perturbing noise.

18. The apparatus of claim 17 wherein said processing means first operation further comprises first means for selecting arbitrarily one of said first and second gain values, and second means for selecting the other of the first and second gain values to minimize the magnitude.

19. The apparatus of claim 18 wherein the circuit output signal magnitude further comprises one of an absolute value of the sum signal and an efficient value of the sum signal.

20. The apparatus of claim 19 wherein the first and second selecting means further comprise a set of linear equations in which the amplifier gain values are the unknowns, and a calculation module processing said equation set to solve the unknowns.

21. The apparatus of claim 20 wherein the calculation module comprises a microprocessor.