Methods for harmonic imaging with ultrasound

  • US 5,733,527 A
  • Filed: 07/29/1996
  • Issued: 03/31/1998
  • Est. Priority Date: 09/28/1994
  • Status: Expired due to Term
First Claim
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1. A method for ultrasonic harmonic imaging comprising:

  • introducing a contrast agent comprising microbubbles into an object or body wherein said contrast agent has the property of radiating imagable ultrasonic energy at a frequency that is different from the resonant frequency of the microbubbles;

    transmitting ultrasonic energy at a fundamental frequency from an ultrasonic source to said object or body wherein the transmitted ultrasonic energy causes said contrast agent to radiate ultrasonic energy at frequencies other than the fundamental frequency with an efficiency greater than a free air bubble; and

    imaging at least a portion of said object or body utilizing at least one frequency other than said fundamental frequency.

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