Electrochemical-enzymatic sensor
First Claim
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1. An electrochemical-enzymatic sensor for use in determining the concentration of glucose and other substances in body fluids, comprising:
- an oxygen sensor comprising a sensor electrode means for determining an oxygen content, the sensor electrode means being of an electrocatalytically inactive carbon selected from the group consisting of vitreous carbon, pyrographite, sputtered carbon, sputtered graphite and amorphous hydrogenated carbon;
a counterelectrode;
a reference electrode;
an enzyme-containing layer disposed before the sensor electrode means; and
a diaphragm of biocompatible, hydrophilic, oxygen-permeable material covering the enzyme layer and retaining the enzyme.
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Abstract
An electrochemical-enzymatic sensor for the determination of substances, in particular glucose, in body fluids, which possesses a good long-term stability, includes: a sensor electrode of electrocatalytically inactive carbon, a counterelectrode, a reference electrode, an enzyme-containing layer located before the sensor electrode, and a diaphragm of biocompatible, hydrophilic, oxygen-permeable material covering the enzyme layer toward the body fluid and retaining the enzyme.
233 Citations
15 Claims
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1. An electrochemical-enzymatic sensor for use in determining the concentration of glucose and other substances in body fluids, comprising:
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an oxygen sensor comprising a sensor electrode means for determining an oxygen content, the sensor electrode means being of an electrocatalytically inactive carbon selected from the group consisting of vitreous carbon, pyrographite, sputtered carbon, sputtered graphite and amorphous hydrogenated carbon; a counterelectrode; a reference electrode; an enzyme-containing layer disposed before the sensor electrode means; and a diaphragm of biocompatible, hydrophilic, oxygen-permeable material covering the enzyme layer and retaining the enzyme. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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Specification