Methods of using and screening extended wear ophthalmic lenses

  • US 5,776,999 A
  • Filed: 07/17/1996
  • Issued: 07/07/1998
  • Est. Priority Date: 09/06/1994
  • Status: Expired due to Term
First Claim
Patent Images

1. A method of using a contact lens as an extended wear lens, said lens having ophthalmically compatible inner and outer surfaces, said lens being suited to extended periods of wear in continuous, intimate contact with ocular tissue and ocular fluids, said lens comprising a polymeric material which has a high oxygen permeability and a high water permeability, said polymeric material being formed from polymerizable materials including:

  • (a) at least one oxyperm polymerizable material; and

    (b) at least one ionoperm polymerizable material,wherein said lens allows oxygen permeation in an amount sufficient to maintain corneal health and wearer comfort during a period of extended, continuous contact with ocular tissue and ocular fluids,wherein said lens allows ion or water permeation via ion or water pathways in an amount sufficient to enable the lens to move on the eye such that corneal health is not substantially harmed and wearer comfort is acceptable during a period of extended, continuous contact with ocular tissue and ocular fluids,wherein said ionoperm polymerizable material, if polymerized alone, would form a hydrophilic polymer having a water content of at least 10 weight percent upon full hydration, andwherein said ophthalmic lens has an oxygen transmissibility of at least about 70 barrers/mm and an ion permeability characterized either by (1) an Ionoton Ion Permeability Coefficient of greater than about 0.2×

    10-6 cm2 /sec or (2) an Ionoflux Diffusion Coefficient of greater than about 1.5×

    10-6 mm2 /min, wherein said ion permeability is measured with respect to sodium ions,said method comprising the steps of;

    (a) applying said lens to the ocular environment; and

    (b) allowing said lens to remain in intimate contact with the ocular environment for a first period of at least 24 hours.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×