Intradermal drug delivery device and method for intradermal delivery of drugs
First Claim
1. An intradermal drug delivery device for delivering a liquid drug to a subject via the subject'"'"'s skin, comprising:
- (a) a housing having a lower surface for application to the skin of the subject;
(b) means for affixing the housing in position with the lower surface in contact with the subject'"'"'s skin;
(c) a plurality of drug reservoirs within the housing;
(d) an outlet cavity in communication with the plurality of drug reservoirs;
(e) a single hollow needle associated with the outlet cavity extending through the lower surface, having an inner end communicating with the outlet cavity and an outer end projecting outwards a sufficient distance so as to penetrate through the epidermis and into the dermis when the housing is pressed against the skin; and
(f) means for actively discharging the drug from the drug reservoir to the subject'"'"'s skin via the needle;
wherein the lower surface is shaped such that when it is pressed against the skin a substantial proportion of the pressure applied to the skin is directed through the outer end of the needle.
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0 Petitions
Accused Products
Abstract
An intradermal drug delivery device for delivering a liquid drug to a subject via the subject'"'"'s skin includes a housing having a lower surface provided with an adhesive coating for adhering the housing to the subject'"'"'s skin. An expansible-contractible chamber within the housing defines a reservoir which is expanded upon being filled with the drug and contracted to dispense the drug. A hollow needle extends through the lower surface of the housing and has an inner end which communicates with the reservoir and an outer end which projects outwardly of the housing a short distance to penetrate through the epidermis and into the dermis of the subject'"'"'s skin when the housing is adhered thereto. The device permits delivery of drugs of relatively large molecular size and at slow rates which can be precisely controlled. A method of delivering a liquid drug intradermally includes adhering the intradermal delivery device to the skin of the subject and activating the means for actively discharging the at least one drug from the reservoir to the subject'"'"'s skin via the needle.
703 Citations
32 Claims
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1. An intradermal drug delivery device for delivering a liquid drug to a subject via the subject'"'"'s skin, comprising:
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(a) a housing having a lower surface for application to the skin of the subject; (b) means for affixing the housing in position with the lower surface in contact with the subject'"'"'s skin; (c) a plurality of drug reservoirs within the housing; (d) an outlet cavity in communication with the plurality of drug reservoirs; (e) a single hollow needle associated with the outlet cavity extending through the lower surface, having an inner end communicating with the outlet cavity and an outer end projecting outwards a sufficient distance so as to penetrate through the epidermis and into the dermis when the housing is pressed against the skin; and (f) means for actively discharging the drug from the drug reservoir to the subject'"'"'s skin via the needle;
wherein the lower surface is shaped such that when it is pressed against the skin a substantial proportion of the pressure applied to the skin is directed through the outer end of the needle. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32)
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Specification