Method and apparatus for the measurement of blood sugar

• US 5,889,585 A
• Filed: 09/24/1997
• Issued: 03/30/1999
• Est. Priority Date: 09/24/1996
• Status: Expired due to Term

• Current Assignee: LRE Technology Partner GmbH
• Original Assignee: LRE Technology Partner GmbH
• Inventors: Markart, Ernst
• Primary Examiner(s): KIM, ROBERT H
• Application Number:
  US08/936,644
• Time in Patent Office: 552 Days
• Field of Search: 356/39-42, 356/445-448, 356/73, 436/164-172, 422/58, 422/82.05, 422/82.09
• US Class Current: 356/39
• CPC Class Codes: G01N 21/8483 Investigating reagent band test-element handling not specific to a test method G01N33/4875; analytical elements specific to chemical analysis of biological material G01N33/52; autometer with reagent band G01N35/04

Abstract

In an apparatus and method for detecting the concentration of a substance in a fluid, such as the concentration of sugar in blood, the measuring field of a test strip to which the fluid to be tested in applied is divided into two separate measuring areas. The change in the light reflection or light transmission capacity of the two measuring areas is then detected separately at repetitive time intervals, and in comparing the changes in light reflectivity or light transmission of the two measuring areas over time, perceived differences in the changes occurring in the two areas are evaluated to provide useful information.

Claims

1. A method for measuring the concentration of a substance in a fluid wherein the measuring fluid is applied to a measuring field (14), consisting of hydrophilic material, of a test strip (12) and the change of the optical reflection or transmission capacity in the area of the measuring field (14) effected thereby is detected, characterized in that the measuring field (14) is divided into at least two measuring areas (26,28), which are separately measured, and that an indicator (20) is actuated, when after a pre-given time (t1, t2;

t) the difference of the measured values of the two measuring areas (26,

     28) exceeds a pre-determined value, to indicate that the measuring field has not been uniformly wetted.

2. The method according to claim 1, characterized in that the two measuring areas (26, 28) are measured at the same pre-given time point (t) and that the measured values (R1, R2) are compared with one another.

3. The method according to claim 1, characterized in that for each measuring area (26, 28) the time (t1, t2) is measured which is necessary for the change in the reflection or transmission capacity to reach a pre-given value (R2) and that upon the exceeding of a pre-given time interval Δ

t an indicator (20) is actuated.

4. The method according to claim 1, characterized in that the change of the reflection and transmission capacity over time and size of the measuring areas (26, 28) is determined and an indicator (20) is actuated if the sensed change of the reflection or transmission capacity deviates from a pre-given set value by more than a pre-given amount.

5. An apparatus for measuring the concentration of a substance in a liquid, by means of optical evaluation of a measuring field (14) of a test strip (12) containing the fluid to be measured, including a strip support (10) for the test strip (20), a measuring optic system (16), an evaluation circuit (18) and an indicator unit (12), characterized in that the measuring optic system (16) has at least two sensing units (22, 24, 30;

22, 36, 24,

     38) for sensing at least two different measuring areas (26,

     28) to produce measured values for each of said two measuring areas, and in that the evaluation circuit (18) produces a signal, indicated by the indicator unit (20), when the difference between said two measured values for said two measuring areas exceeds a predetermined value, to indicate that the measuring field has not been uniformly wetted.

6. An apparatus according to claim 5, characterized in that each of the sensing units has a light emitter and a light receiving unit (22, 36;

24,

     38) which are directed onto the different measuring areas (26,

     28) and are simultaneously actuatable.

7. An apparatus according to claim 5, characterized in that the sensing units each have a light emitter (22, 24) which is directed onto the different measuring areas (26, 28) and which are actuatable at different time points and that the measuring field (14) is sensed by a common detector (30) of the sensing unit.