Product and method for treating joint disorders in vertebrates

• US 5,916,565 A
• Filed: 03/07/1997
• Issued: 06/29/1999
• Est. Priority Date: 03/08/1996
• Status: Expired due to Term

• Current Assignee: In Clover, Inc.
• Original Assignee: In Clover, Inc.
• Inventors: Rose, Rebecca, Chrisope, Gerald L.
• Primary Examiner(s): Witz, Jean C.
• Assistant Examiner(s): HANLEY, SUSAN MARIE
• Application Number:
  US08/813,560
• Time in Patent Office: 844 Days
• Field of Search: 424/195.1
• US Class Current: 424/756
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 36/23 Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
• CPC Class Codes: A61K 36/29 Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
• CPC Class Codes: A61K 36/48 Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
• CPC Class Codes: A61K 36/67 Piperaceae (Pepper family), e.g. Jamaican pepper or kava
• CPC Class Codes: A61K 36/71 Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
• CPC Class Codes: A61K 36/81 Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
• CPC Class Codes: A61K 36/896 Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
• CPC Class Codes: A61K 36/9066 Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
• CPC Class Codes: A61K 36/9068 Zingiber, e.g. garden ginger

Abstract

A composition and method of use is disclosed that, when administered to an animal, is capable of arresting the inflammatory response in affected tissues and facilitates the repair and maintenance of damaged tissues in the joints of vertebrates. The combination of natural physiological metabolites and herbal phytochemicals is used to treat connective tissue diseases, the composition is preferably orally administered. One embodiment of the composition includes chondroitin sulfate and glucosamine that, when ingested by a vertebrate, suppresses the degradation of connective tissue by an autoimmune response. A composition of the present invention includes a palatability agent, an herbal phytochemical, and a metabolic precursor that act to increase blood circulation, thereby enhancing transport of the phytochemical and metabolic precursors to an affected site whereby deleterious inflammatory byproducts are removed.

Claims

1. A composition for the treatment of arthritis, joint stiffness, joint mobility and joint pain in vertebrates, based on 25 pounds of body weight, consisting essentially of a palatability agent, from about 2 to 55 mg of cayenne, from about 50 to 220 mg of ginger, from about 50 to 400 mg of tumeric, from about 400 to 3000 mg of yucca, from about 200 to 2000 mg of Devil'"'"'s Claw, from about 100 to 750 mg of nettle leaf, from about 20 to 500 mg of Black Cohosh, from about 100 to 800 mg of alfalfa, from about 20 to 400 mg of celery seeds, from about 50 to 2000 mg of D-glucosamine HCl;

and from about 50 to 2000 mg of mucopolysaccharides.

2. The composition of claim 1, wherein the vertebrate is selected from the group consisting of a dog, a horse and a cat.

3. The composition of claim 1, wherein said composition has a flavor desirable to the vertebrate to be treated.

4. The composition of claim 1, wherein said composition diminishes the oxidative effect of free radicals in joints.

5. The composition of claim 1, wherein said composition diminishes the degradation of synovial fluid hyaluronin in joints.

6. The composition of claim 1, wherein said composition suppresses the immune response of said vertebrate.