Microemulsion preconcentrates comprising cyclosporins
First Claim
1. A pharmaceutical composition wherein said composition is a microemulsion preconcentrate comprising a cyclosporin dissolved in a solvent system, said solvent system comprising a hydrophilic component, a hydrophobic component, and a surfactant, wherein the hydrophilic component is propylene carbonate or polyethylene glycol having average molecular weight of less than 1000.
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Abstract
A pharmaceutical composition in the form of a microemulsion preconcentrate comprising a cyclosporin dissolved in a solvent system further comprising a hydrophobic component, a hydrophilic component, and a surfactant, wherein either the hydrophobic component is selected from tocol, tocopherols, tocotrienols, and derivatives thereof, or the hydrophilic component is selected from propylene carbonate or polyethylene glycol having an average molecular weight of less than 1000.
46 Citations
14 Claims
- 1. A pharmaceutical composition wherein said composition is a microemulsion preconcentrate comprising a cyclosporin dissolved in a solvent system, said solvent system comprising a hydrophilic component, a hydrophobic component, and a surfactant, wherein the hydrophilic component is propylene carbonate or polyethylene glycol having average molecular weight of less than 1000.
Specification