Medical diagnostic instrument using light-to-frequency converter

• US 6,011,985 A
• Filed: 11/18/1996
• Issued: 01/04/2000
• Est. Priority Date: 04/01/1994
• Status: Expired due to Term

• Current Assignee: University of South Florida (State University System of Florida)
• Original Assignee: University of South Florida (State University System of Florida)
• Inventors: Athan, Stephan Peter, Scharf, John Edward
• Primary Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US08/751,645
• Time in Patent Office: 1,142 Days
• Field of Search: 600/310, 600/322, 600/323, 600/324, 600/473, 600/476, 600/479, 128/903, 356/41, 250/214 A, 250/214 L
• US Class Current: 600/322
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/7257 using Fourier transforms
• CPC Class Codes: A61B 5/726 using Wavelet transforms

Abstract

A diagnostic instrument for determining a cardiovascular system parameter. In one embodiment, the instrument takes the form of a portable pulse oximeter comprising a light to frequency converter (LFC) as a sensor. Also provided is a light to frequency converter comprising a photoresistor and capacitor in circuit communication with an inverting Schmitt trigger and configured such that the inverter generates a periodic electrical signal corresponding to the amount of electromagnetic radiation illuminating the photoresistor.

Claims

1. A system for determining a pulse rate of a cardiovascular system comprising:

a. an electromagnetic radiation source for illumination of a volume of intravascular blood with electromagnetic radiation, the electromagnetic radiation having at least one frequency component having an intensity, the intensity of the at least one frequency component of the electromagnetic radiation being altered by interaction with the volume of intravascular blood thereby generating an optical signal from the interaction of the at least one frequency component of the electromagnetic radiation with the volume of intravascular blood, the optical signal having an intensity;

b. a light-to-frequency converter having an electromagnetic radiation sensor electrically connected to an electronic signal generator, said electromagnetic radiation sensor being optically coupled to said electromagnetic radiation source for reception of the optical signal and said electronic signal generator generating a periodic electrical signal responsive to said electromagnetic radiation sensor, the periodic electrical signal comprising a digital pulse train having pulses, the timing of the pulses of the electrical signal corresponding to the intensity of the optical signal; and

c. a signal analyzer operatively connected to said light-to-frequency converter for determining from the pulses of the periodic electrical signal the pulse rate of the cardiovascular system.

2. A system for determining a pulse rate of a cardiovascular system according to claim 1 further comprising a display circuit operatively connected to said signal analyzer for presenting a display corresponding to the pulse rate of the cardiovascular system.

3. A system for determining a pulse rate of a cardiovascular system according to claim 1 further comprising a transmitter operatively connected to said signal analyzer for transmitting to a remote receiver a signal corresponding to the pulse rate of the cardiovascular system.

4. A system for determining a pulse rate of a cardiovascular system according to claim 1 wherein said signal analyzer comprises means for determining from the pulses of the periodic electrical signal the pulse rate of the cardiovascular system.

5. A system for determining a respiration rate of a cardiovascular system comprising:

a. an electromagnetic radiation source for illumination of a volume of intravascular blood with electromagnetic radiation, the electromagnetic radiation having at least one frequency component having an intensity, the intensity of the at least one frequency component of the electromagnetic radiation being altered by interaction with the volume of intravascular blood thereby generating an optical signal from the interaction of the at least one frequency component of the electromagnetic radiation with the volume of intravascular blood, the optical signal having an intensity;

b. a light-to-frequency converter having an electromagnetic radiation sensor electrically connected to an electronic signal generator, said electromagnetic radiation sensor being optically coupled to said electromagnetic radiation source for reception of the optical signal and said electronic signal generator generating a periodic electrical signal responsive to said electromagnetic radiation sensor, the periodic electrical signal comprising a digital pulse train having pulses, the timing of the pulses of the electrical signal corresponding to the intensity of the optical signal; and

c. a signal analyzer operatively connected to said light-to-frequency converter for determining from the pulses of the periodic electrical signal the respiration rate of the cardiovascular system.

6. A system for determining a respiration rate of a cardiovascular system according to claim 5, further comprising a display circuit operatively connected to said signal analyzer for presenting a display corresponding to the respiration rate of the cardiovascular system.

7. A system for determining a respiration rate of a cardiovascular system according to claim 5, further comprising a transmitter operatively connected to said signal analyzer for transmitting to a remote receiver a signal corresponding to the respiration rate of the cardiovascular system.

8. A system for determining a respiration rate of a cardiovascular system according to claim 5, wherein said signal analyzer comprises means for determining from the pulses of the periodic electrical signal the respiration rate of the cardiovascular system.

9. A system for determining an intravascular volume status of a cardiovascular system comprising:

a. an electromagnetic radiation source for illumination of a volume of intravascular blood with electromagnetic radiation, the electromagnetic radiation having at least one frequency component having an intensity, the intensity of the at least one frequency component of the electromagnetic radiation being altered by interaction with the volume of intravascular blood thereby generating an optical signal from the interaction of the at least one frequency component of the electromagnetic radiation with the volume of intravascular blood, the optical signal having an intensity;

b. a light-to-frequency converter having an electromagnetic radiation sensor electrically connected to an electronic signal generator, said electromagnetic radiation sensor being optically coupled to said electromagnetic radiation source for reception of the optical signal and said electronic signal generator generating a periodic electrical signal responsive to said electromagnetic radiation sensor, the periodic electrical signal comprising a digital pulse train having pulses, the timing of the pulses of the electrical signal corresponding to the intensity of the optical signal; and

c. a signal analyzer operatively connected to said light-to-frequency converter for determining from the pulses of the periodic electrical signal the intravasular volume status of the cardiovascular system.

10. A system for determining an intravascular volume status of a cardiovascular system according to claim 9, further comprising a display circuit operatively connected to said signal analyzer for presenting a display corresponding to the intravascular volume status of the cardiovascular system.

11. A system for determining an intravascular volume status of a cardiovascular system according to claim 9, further comprising a transmitter operatively connected to said signal analyzer for transmitting to a remote receiver a signal corresponding to the intravascular volume status of the cardiovascular system.

12. A system for determining an intravascular volume status of a cardiovascular system according to claim 9, wherein said signal analyzer comprises means for determining from the pulses of the periodic electrical signal the intravascular volume status of the cardiovascular system.

13. A method of determining a parameter of a cardiovascular system comprising:

a. illuminating a volume of intravascular blood with electromagnetic radiation, the electromagnetic radiation having at least one frequency component having an intensity, the intensity of the at least one frequency component of the electromagnetic radiation being altered by interaction with the volume of intravascular blood thereby generating an optical signal from the interaction of the at least one frequency component of the electromagnetic radiation with the volume of intravascular blood, the optical signal having an intensity;

b. optically coupling a light-to-frequency converter to receive the optical signal;

c. generating with the light-to-frequency converter a periodic electrical signal comprising a digital pulse train having pulses, the timing of the pulses of the electrical signal corresponding to a parameter of the optical signal;

d. determining data values corresponding to the pulses of the periodic electrical signal; and

e. determining the cardiovascular system parameter from the data values.

14. A method of determining a parameter of a cardiovascular system according to claim 13, wherein said step of determining the cardiovascular system parameter comprises determining an oxygen saturation level of hemoglobin within the volume of blood.

15. A method of determining a parameter of a cardiovascular system according to claim 13, wherein said step of determining the cardiovascular system parameter comprises determining a pulse rate of the cardiovascular system.

16. A method of determining a parameter of a cardiovascular system according to claim 13, wherein said step of determining the cardiovascular system parameter comprises determining a respiration rate of the cardiovascular system.

17. A method of determining a parameter of a cardiovascular system according to claim 13, wherein said step of determining the cardiovascular system parameter comprises determining an intravascular volume status of the cardiovascular system.