Pharmaceutical compositions containing dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing them and their use in treating clot formation

  • US 6,015,577 A
  • Filed: 04/12/1995
  • Issued: 01/18/2000
  • Est. Priority Date: 08/13/1986
  • Status: Expired due to Term
First Claim
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1. A pharmaceutical composition for oral administration comprising:

  • a first component selected from the group consisting of dipyridamole, and the pharmaceutically acceptable salts thereof; and

    a second component selected from the group consisting of acetylsalicylic acid and the pharmaceutically acceptable salts thereof;

    said first and second components being present in a weight ratio in the range between 8;

    1 and 100;

    1;

    a pharmaceutically acceptable acid excipient formulated together with said first component in the form of granules provided with a coating made up of 50 to 100% of lacqueurs which are insoluble in acid but soluble in intestinal juices and 50 to 0% of lacqueurs which are insoluble in both gastric and intestinal juices, and said acid excipient being in a ratio of at least one equivalent of said acid excipient to 1 mol of said first component;

    said second component being present in the form of a tablet; and

    all components being contained together within a capsule.

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