Composition for treating abnormal conditions of the epithelium of bodily orifices

  • US 6,017,554 A
  • Filed: 09/21/1998
  • Issued: 01/25/2000
  • Est. Priority Date: 07/06/1993
  • Status: Expired due to Term
First Claim
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1. A topical composition for treating conditions of the epithelium of the rectal, vaginal, urethral, oral, nasal, ocular, and auditory canal orifices, brought about by the occurrence of any of fungal and bacterial infections, leukoplakia, penetration of bacterial toxins, living unicellular microorganisms, vaginitis, endometriosis, Porphyromonoas gingivalis, Actinobacillus actinomycetemcomitans, Pseudomonades, Candid species and leukoplakia vulvae, said composition comprising a topical preparation selected from the group consisting of liquid solutions, suspensions, semi-solids, salves, creams, and suppositories, wherein said topical preparation contains chlorine dioxide in a concentration in the range of about 0.005% to about 2.0% and a phosphate compound comprising trisodium phosphate, wherein the concentration of the phosphate compound is in a range of about 0.02% to about 3.0% to retard escape of the chlorine dioxide from said topical preparation, said topical preparation being at a pH in the range of about 6.0 to about 7.4, thereby increasing the shelf life and efficacy of said topical preparation.

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