Optimization of pacing parameters based on measurement of integrated acoustic noise

• US 6,044,298 A
• Filed: 10/13/1998
• Issued: 03/28/2000
• Est. Priority Date: 10/13/1998
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Salo, Rodney W., Nugent, Kevin G.
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): EVANISKO, GEORGE ROBERT
• Application Number:
  US09/170,259
• Time in Patent Office: 532 Days
• Field of Search: 607/4-6, 607/9, 607/17, 607/19, 607/23, 607/24
• US Class Current: 607/17
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/36542 controlled by body motion, e.g. acceleration

Abstract

Hemodynamic performance of the heart as a pump is optimized by using an accelerometer and signal processing circuitry to measure total acoustic noise (TAN) over predetermined time periods when a pacemaker is made to function in a variety of modes. By detecting the particular mode associated with minimum TAN, the optimum pacing mode is arrived at.

Claims

1. Apparatus for optimizing a pacing mode of a cardiac rhythm management device, comprising:

(a) an implantable cardiac rhythm management device for producing cardiac stimulating pulses at timed intervals having a plurality of programmable parameters, wherein the implantable device has a plurality of different pacing modes and wherein different parameters are used for different pacing modes;

(b) means for applying said pulses to cardiac tissue at least one site to stimulate the heart;

(c) means for measuring acoustic noise over predetermined portions of a cardiac cycle during successive cardiac cycles;

(d) means for integrating the measured acoustic noise over the predetermined portions of the cardiac cycle;

(e) means for varying the programmable parameters of the cardiac rhythm management device in one pacing mode and for varing different programmable parameters in at least one other pacing mode;

(f) means for detecting one of a minimum integrated acoustic noise measurement and maximum ratio of integrated acoustic noise as said parameters are varied for use in different pacing modes; and

(g) means for setting the pacing mode of the cardiac rhythm management device to the parameters associated with said one of the minimum integrated acoustic noise measurement and maximum ratio of integrated acoustic noise measurements to supply pulses to stimulate the heart.

2. The apparatus as in claim 1 wherein the cardiac rhythm management device is a cardiac pacemaker.

3. The apparatus as in claim 1 wherein the cardiac rhythm management device is a combination pacemaker/defibrillator.

4. The apparatus of any one of claims 1 or 3 wherein the means for measuring integrated acoustic noise comprises:

(a) an accelerometer for sensing acoustic energy emitted from the heart and producing a raw signal proportional thereto;

(b) means for filtering said raw signal to attenuate variations in the raw signal due to respiratory activity;

(c) means for full-wave rectifying the filtered raw signal; and

(d) means for integrating the rectified filtered raw signal over said predetermined portions of the cardiac cycles.

5. The apparatus as in claim 4 wherein the accelerometer is totally implanted within the implantable cardiac rhythm management device.

6. The apparatus as in claim 4 wherein the means for filtering is a high-pass filter having a corner frequency of about 1.0 Hz.

7. The apparatus as in claim 6 wherein the means for filtering further includes a band-pass filter having a pass band between about 0.1 Hz and 140 Hz.

8. The apparatus as in claim 4 and further including:

(a) means for normalizing the integrated rectified filtered raw signal over the predetermined portions of the cardiac cycle.

9. The apparatus as in claim 8 wherein the means for normalizing comprises:

(a) means for dividing the integrated acoustic noise by a ratio of a product of a sampling rate of the means for integrating and a length of the cardiac cycle.

10. The apparatus of claim 1 wherein the means for detecting a minimum integrated acoustic noise measurement includes memory means for storing the integrated acoustic noise measurements and the programmable parameters, and means for comparing said integrated acoustic noise measurements stored in said memory means to one another.

11. The apparatus as in claim 1 wherein the predetermined portions of the cardiac cycle used is one complete cardiac cycle and the integrated acoustic noise comprises a total acoustic noise measurement for said cardiac cycle.

12. The apparatus of claim 1 wherein;

the predetermined portions of the cardiac cycle comprises the filling and the ejection phases,

the means for measuring acoustic noise measures the acoustic noise during the filling and the ejection phases,

the means for integrating the measured acoustic noise integrates the filling noise over the filling phase and integrates the ejection acoustic noise over the ejection phase,

the means for detecting one of the minimum and maximum integrated acoustic noises determines the ratio of the measured integrated acoustic noise of the ejection phase over the integrated acoustic noise of the filling phase and compares the ratios for different pacing modes selecting the maximum ratio and setting the pacing mode of the cardiac rhythm management device to the pacing mode with the maximum ratio of ejection to filling integrated acoustic noise.