Syringe with automatically withdrawable of piston rod

• US 6,045,537 A
• Filed: 12/02/1997
• Issued: 04/04/2000
• Est. Priority Date: 06/02/1995
• Status: Expired due to Fees

• Current Assignee: Novo Nordisk A/S
• Original Assignee: Novo Nordisk A/S
• Inventors: Klitmose, Lars Peter
• Primary Examiner(s): Coggins, Wynn Wood
• Assistant Examiner(s): NGUYEN, ANH TUAN TUONG
• Application Number:
  US08/973,109
• Time in Patent Office: 854 Days
• Field of Search: 604/207, 604/208, 604/209, 604/211, 604/232, 604/233, 604/234, 604/151, 604/155, 604/224, 222/325, 222/327
• US Class Current: 604/224
• CPC Class Codes: A61M 2005/2414 from the side
• CPC Class Codes: A61M 2005/31518 designed to reduce the overall size of an injection device, e.g. using flexible or pivotally connected chain-like rod members
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/31535 Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
• CPC Class Codes: A61M 5/31543 piston rod reset means, i.e. means for causing or facilitating retraction of piston rod to its starting position during cartridge change
• CPC Class Codes: A61M 5/31586 performed by rotationally moving or pivoted actuator, e.g. an injection lever or handle

Abstract

A syringe for injection of doses of a medicine from an exchangeable cartridge has a housing comprising a cartridge holder and a dosing mechanism by which a dose is set and injected by successively advancing a piston rod to press a piston into the cartridge. The dosing mechanism comprises a threaded spindle and a nut member cooperating with the spindle. A dose is set by relative rotation of the spindle and nut member whereby the nut member is moved along the spindle. The position of the nut member on the spindle defines how far the piston rod is advanced. The spindle and the nut are locked against relative rotation when the dosing mechanism is not operated to set a dose. Access to the cartridge holder is obtained by opening a lid connected to the housing and coupled to the dosing mechanism in such a way that the locking of the nut element in its position on the spindle is released when the lid is opened, and the opening movement of the lid is transmitted to a piston rod retraction mechanism.

Claims

1. A syringe for dosed injection of a medicine from a replaceable cartridge, said syringe comprising:

a housing comprising a cartridge holder for receiving a replaceable cartridge of the type having a piston which can be forced into the cartridge to press out a dose of medicine;

a lid coupled to the housing for movement between closed and open positions, wherein the lid, when in the latter position, provides access to the cartridge holder for changing cartridges; and

a dosing mechanism including a piston rod moveable within the housing for administering doses of medicine from a cartridge;

a threaded spindle;

a nut member selectively engageable with the spindle so that relative rotation of the spindle and the nut member moves the nut member along the spindle; and

a coupling mechanism for moving the piston rod during an injection a distance dependent upon the relative position of the nut member on the spindle; and

wherein the lid is coupled to the dosing mechanism so that, when the lid is closed, relative movement between the spindle and nut occurs only when the nut member and spindle are rotated relative to one another and, when the lid is opened, the nut member can be moved relative to the spindle without relative rotation between the spindle and nut member.

2. A syringe according to claim 1, further comprising a piston rod retraction mechanism coupled to the lid for automatically moving the piston rod into a withdrawn position, responsive to opening the lid, to allow cartridges to be removed from, and mounted in, the cartridge holder.

3. A syringe according to claim 2, wherein the lid is mounted on the housing for sliding movement in an axial direction of the syringe.

4. A syringe according to claim 3, wherein the piston rod withdrawal mechanism includes a piston rod retraction member rigidly connected to the lid and having a engagement member engaging means engaging the piston rod to move the piston rod back into its withdrawn position the lid slides in the axial direction to provide access to the cartridge holder.

5. A syringe according to claim 4, wherein the piston rod retraction member has means engaging the dosing mechanism to release the nut element from engagement with the spindle during an initial part of the sliding movement of the lid when the lid slides in a direction to provide access to the cartridge holder.

6. A syringe according to claim 5, further comprising a detent mechanism coupled between the lid and the housing which prevents the lid from being closed unless it has first been fully opened.

7. A syringe according to claim 6, wherein housing has linear toothing with axially spaced recesses at either end thereof, wherein the detent mechanism comprises a pawl mounted on a part rigidly connected to the lid for engaging the toothing for one-way detention of movement, and wherein the recesses allow the pawl to change its direction of detention.