Medical diagnostic analysis system

• US 6,063,026 A
• Filed: 03/22/1996
• Issued: 05/16/2000
• Est. Priority Date: 12/07/1995
• Status: Expired due to Term

• Current Assignee: The Carbon Basis Company Ltd..
• Original Assignee: The Carbon Basis Company Ltd..
• Inventors: Kane, Patricia, Schauss, Mark A.
• Primary Examiner(s): Gilbert, Samuel G.
• Application Number:
  US08/620,385
• Time in Patent Office: 1,516 Days
• Field of Search: 128/630, 128/920, 128/921, 128/923, 128/924, 128/898, 128/670, 600/300
• US Class Current: 600/300
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 15/00 ICT specially adapted for medical reports, e.g. generation or transmission thereof
• CPC Class Codes: G16H 20/10 relating to drugs or medications, e.g. for ensuring correct administration to patients
• CPC Class Codes: G16H 50/20 for computer-aided diagnosis, e.g. based on medical expert systems
• CPC Class Codes: G16H 70/40 relating to drugs, e.g. their side effects or intended usage
• CPC Class Codes: Y10S 128/923 by comparison of patient data to other data

Abstract

The present invention is a computerized medical diagnostic method. It includes a first database containing a correlation of a plurality of diseases with a plurality of indicators associated with each such disease. A second database includes human experience test results associated with each indicator. An individual'"'"'s test results are then compared with the second database data to determine presence levels for each indicator. Thereafter the presence levels are compared with the data in the first database to provide a pattern matching determination of diseases associated with the various indicator presence levels.

The presence level indicators for an individual may be affected by many environmental and/or personal factors such as age, sex, race, pregnancy, residence location, previous or current diseases, previous or current drug usage, etc., all of which are factors to be considered in creating an accurate analysis system. The present invention provides a method for correlating such factors with the various test indicators to identify therapeutic and/or contraindicated treatments and drugs.

Claims

1. A medical diagnostic method utilizing a computerized system having a means for data storage and a means for data processing, comprising:

a. storing a first database in said means for data storage, said first database having indicator data including human experience test result levels associated with each of a plurality of indicators;

b. storing a second database in said means for data storage, said second database having indicator data including a plurality of drugs and a plurality of indicators that are associated with each said drug;

c. inputting test results for an individual into said means for data processing, said test results including specific indicator levels associated with said individual;

d. determining an indicator presence level for each said indicator by comparing said specific indicator levels with said indicator data of said first database utilizing said means for data processing;

e. comparing said indicator presence levels with said indicator data of said second database utilizing said means for data processing, and providing a determination related to the effect of particular ones of said drugs in said individual.

2. A method as described in claim 1, wherein said indicator data of said second database includes a correlation of said drugs with increased and decreased levels of said indicators.

3. A method as described in claim 1, wherein said step of determining an indicator presence level includes the further step of determining whether said indicator presence level is increased or decreased.

4. A method as described in claim 1, wherein said indicator data of said first database includes a correlation of high, low and mean human experience test results for said indicators.

5. A method as described in claim 4, wherein said step of determining an indicator presence level includes the further step of determining a percent status value for each said indicator, said percent status value being determined from the relationship:

##EQU3##

6. A method as described in claim 5, wherein said step of determining an indicator presence level includes the further step of determining whether said percent status value is greater than 25% or less than -25%.

7. A method as described in claim 1, wherein said determination related to the effect of particular ones of said drugs in said individual includes a determination of drugs that cause or aggravate said indicator presence levels.

8. A method as described in claim 7, further including the step of:

f. determining those drugs that are most commonly identified as causing or aggravating said indicator presence levels.

9. A method as described in claim 1, wherein steps a-e are performed on two different dates utilizing individual test results created on said two different dates to produce a said determination on each of said two different dates;

and

comparing said determinations from said two different dates to identify changes in said determinations.

10. A medical diagnostic method utilizing a computerized system having a means for data storage and a means for data processing, comprising:

a. storing a first database in said means for data storage;

said first database having indicator data including human experience test result levels associated with each of a plurality of indicators;

b. storing a second database in said means for data storage, said second database having indicator data including a plurality of pharmacological agents and a plurality of indicators that are associated with each said agent;

c. inputting test results for an individual into said means for data processing, said test results including specific indicator levels associated with said individual;

d. determining an indicator presence level for each said indicator by comparing said specific indicator levels with said indicator data of said first database utilizing said means for data processing;

e. comparing said indicator presence levels with said indicator data of said second database utilizing said means for data processing, and providing a determination related to the effect of particular ones of said agents in said individual.

11. A method as described in claim 10, wherein said indicator data of said second database includes a correlation of said agents with increased and decreased levels of said indicators.

12. A method as described in claim 10, wherein said step of determining an indicator presence level includes the further step of determining whether said indicator presence level is increased or decreased.

13. A method as described in claim 10, wherein said indicator data of said first database includes a correlation of high, low and mean human experience test results for said indicators.

14. A method as described in claim 13, wherein said step of determining an indicator presence level includes the further step of determining a percent status value for each said indicator, said percent status value being determined from the relationship:

##EQU4##

15. A method as described in claim 14, wherein said step of determining an indicator presence level includes the further step of determining whether said percent status value is greater than 25% or less than -25%.

16. A method as described in claim 10, wherein said determination related to the effect of particular ones of said agent in said individual includes a determination of agents that normalize said indicator presence levels.

17. A method as described in claim 16, further including the step of:

f. determining those agents that are most commonly identified as normalizing said indicator presence levels.

18. A method as described in claim 10, wherein steps a-e are performed on two different dates utilizing individual test results created on said two different dates to produce a said determination on each of said two different dates;

and

comparing said determinations from said two different dates to identify changes in said determinations.

19. A medical diagnostic method utilizing a computerized system having a means for data storage and a means for data processing, comprising:

a. storing a first database in said means for data storage, said first database having indicator data including human experience test result levels associated with each of a plurality of indicators, wherein said indicator data of said first database includes a correlation of high, low and mean human experience test results for each of said indicators;

b. storing a second database in said means for data storage, said second database having indicator data including a plurality of drugs and a plurality of indicators that are associated with each said drug, wherein said indicator data of said second database includes a correlation of said drugs with increased and decreased levels of said indicators;

c. inputting test results for an individual into said means for data processing, said test results including specific indicator levels associated with said individual;

d. determining an indicator presence level for each said indicator by comparing said specific indicator levels with said indicator data of said first database utilizing said means for data processing, and wherein said step of determining an indicator presence level includes the further step of determining whether said indicator presence level is increased or decreased;

e. comparing said indicator presence levels with said indicator data of said second database utilizing said means for data processing, and providing a determination related to the effect of particular ones of said drugs in said individual.

20. A method as described in claim 19, wherein said step of determining of an indicator presence level includes the further step of determining a percent status value for each said indicator, said percent status value being determined from the relationship:

##EQU5## and wherein said step of determining an indicator presence level includes the further step of determining whether said percent status value is greater than 25% as an indication that said indicator presence level is increased, or less than -25% as an indication that said indicator presence level is decreased.

21. A method as described in claim 20, wherein said determination related to the effect of particular ones of said drugs in said individual includes a determination of drugs that cause or aggravate said indicator presence levels.

22. A method as described in claim 21, wherein steps a-e are performed on two different dates utilizing individual test results created on said two different dates to produce a said determination on each of said two different dates;

and

comparing said determinations from said two different dates to identify changes in said determinations.

23. A method as described in claim 19, further including the step of:

f. determining those drugs that are most commonly identified as causing or aggravating said increased or decreased indicator presence levels.

24. A medical diagnostic method utilizing a computerized system having a means for data storage and a means for data processing, comprising:

a. storing a first database in said means for data storage;

said first database having indicator data including human experience test result levels associated with each of a plurality of indicators, wherein said indicator data of said first database includes a correlation of high, low and mean human experience test results for each of said indicators;

b. storing a second database in said means for data storage, said second database having indicator data including a plurality of pharmacological agents and a plurality of indicators that are associated with each said agent, wherein said indicator data of said second database includes a correlation of said agents with increased and decreased levels of said indicators;

c. inputting test results for an individual into said means for data processing, said test results including specific indicator levels associated with said individual;

d. determining an indicator presence level for each said indicator by comparing said specific indicator levels with said indicator data of said first database utilizing said means for data processing, and wherein said step of determining an indicator presence level includes the further step of determining whether said indicator presence level is increased or decreased;

e. comparing said indicator presence levels with said indicator data of said second database utilizing said means for data processing, and providing a determination related to the effect of particular ones of said agents in said individual.

25. A method as described in claim 24, wherein said step of determining an indicator presence level includes the further step of determining a percent status value for each said indicator, said percent status value being determined from the relationship:

##EQU6## wherein said step of determining an indicator presence level includes the further step of determining whether said percent status value is greater than 25% as an indication that said indicator presence level is increased, or less than -25% as an indication that said indicator presence level is decreased.

26. A method as described in claim 25, wherein said determination related to the effect of particular ones of said agents in said individual includes a determination of agents that normalize said indicator presence levels.

27. A method as described in claim 26, wherein steps a-e are performed on two different dates utilizing individual test results created on said two different dates to produce a said determination on each of said two different dates;

and

comparing said determinations from said two different dates to identify changes in said determinations.

28. A method as described in claim 24, further including the step of:

f. determining those agents that are most commonly identified as normalizing said increased or decreased indicator presence levels.

29. In a medical diagnostic method utilizing a computerized system having a means for data storage and a means for data processing, including the steps of:

a. storing a first database in said means for data storage, said first database having indicator data including human experience test result levels associated with each of a plurality of indicators, wherein said indicator data of said first database includes a correlation of high, low and mean human experience test results for each of said indicators;

b. inputting test results for an individual into said means for data processing, said test results including specific indicator levels associated with said individual;

the improvement therein comprising the steps of;

c. determining an indicator presence level for each said indicator by comparing said specific indicator levels with said indicator data of said first database utilizing said means for data processing, and wherein said step of determining an indicator presence level includes the further step of determining whether said indicator presence level is increased or decreased;

d. storing a second database in said means for data storage, said second database having indicator data including a plurality of drugs and a plurality of indicators that are associated with each said drug, wherein said indicator data of said second database includes a correlation of said drugs with increased and decreased levels of said indicators;

e. comparing said indicator presence levels with said indicator data of said second database utilizing said means for data processing, and providing a determination related to the effect of particular ones of said drugs in said individual.

30. In a method as described in claim 29, wherein said step of determining of an indicator presence level includes the further step of determining a percent status value for each said indicator, said percent status value being determined from the relationship:

##EQU7## the improvement therein comprising the further step of determining whether said percent status value is greater than 25% as an indication that said indicator presence level is increased, or less than -25% as an indication that said indicator presence level is decreased.

31. In a method as described in claim 30, wherein said determination related to the effect of particular ones of said drugs in said individual includes the improvement of a determination of drugs that cause or aggravate said indicator presence levels.

32. In a method as described in claim 31, wherein test results are obtained on two separate days and results are compared, the improvement therein comprising performing steps a-e on two different dates utilizing individual test results created on said two different dates to produce a said determination on each of said two different dates;

and

comparing said determinations from step (e) from said two different dates to identify changes in said determinations.

33. In a method as described in claim 29, the improvement therein comprising the further step of:

f. determining those drugs that are most commonly identified as causing or aggravating said increased or decreased indicator presence levels.

34. In a medical diagnostic method utilizing a computerized system having a means for data storage and a means for data processing, including the steps of:

a. storing a first database in said means for data storage;

said first database having indicator data including human experience test result levels associated with each of a plurality of indicators, wherein said indicator data of said first database includes a correlation of high, low and mean human experience test results for each of said indicators;

b. inputting test results for an individual into said means for data processing, said test results including specific indicator levels associated with said individual;

the improvement therein comprising the steps of;

c. determining an indicator presence level for each said indicator by comparing said specific indicator levels with said indicator data of said first database utilizing said means for data processing, and wherein said step of determining an indicator presence level includes the further step of determining whether said indicator presence level is increased or decreased;

d. storing a second database in said means for data storage, said second database having indicator data including a plurality of pharmacological agents and a plurality of indicators that are associated with each said agent, wherein said indicator data of said second database includes a correlation of said agents with increased and decreased levels of said indicators;

e. comparing said indicator presence levels with said indicator data of said second database utilizing said means for data processing, and providing a determination related to the effect of particular ones of said agents in said individual.

35. In a method as described in claim 34, wherein said step of determining an indicator presence level includes the further step of determining a percent status value for each said indicator, said percent status value being determined from the relationship:

##EQU8## the improvement therein comprising the further step of determining whether said percent status value is greater than 25% as an indication that said indicator presence level is increased, or less than -25% as an indication that said indicator presence level is decreased.

36. In a method as described in claim 35, wherein said determination related to the effect of particular ones of said agents in said individual includes the improvement of a determination of agents that normalize said indicator presence levels.

37. In a method as described in claim 36, wherein test results are obtained on two separate days and results are compared, the improvement therein comprising performing steps a-e on two different dates utilizing individual test results created on said two different dates to produce a said determination on each of said two different dates;

and

comparing said determinations from step (e) from said two different dates to identify changes in said determinations.

38. In a method as described in claim 34, the improvement therein comprising the further step of:

f. determining those agents that are most commonly identified as normalizing said increased or decreased indicator presence levels.