Multiplex sensor and method of use
First Claim
1. A method for measuring at least one parameter of a sample comprising the steps of:
- (a) illuminating said sample with light;
(b) performing at least two spectroscopic measurements, wherein said at least two spectroscopic measurements are different members of the group consisting of;
infrared absorbance,scattering,diattenuation,emission spectroscopy,photoacoustic spectroscopy,provided that said photoacoustic spectroscopy relates acoustic signal intensity directly to the measurement of said at least one parameter of said sample; and
(c) analyzing said spectroscopic measurements to determine a measurement of said at least one parameter of said sample.
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Accused Products
Abstract
A multiplex sensor and a method of use that provides enhanced selectivity and sensitivity. In this method, one or more parameters of the sample are measured by means of multiple spectroscopic techniques, and the interferences from physiological and spectral variables are reduced or eliminated. In one embodiment of the present invention comprises a multiplex sensor and a method of use that provides enhanced selectivity and sensitivity. One or more parameters of the sample are measured by means of at least two different spectroscopic techniques, wherein the at least two different spectroscopic techniques are selected from the group consisting of:
(a) infrared absorbance
(b) scattering
(c) emission
(d) polarization, and
(e) photoacoustics.
373 Citations
17 Claims
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1. A method for measuring at least one parameter of a sample comprising the steps of:
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(a) illuminating said sample with light; (b) performing at least two spectroscopic measurements, wherein said at least two spectroscopic measurements are different members of the group consisting of; infrared absorbance, scattering, diattenuation, emission spectroscopy, photoacoustic spectroscopy, provided that said photoacoustic spectroscopy relates acoustic signal intensity directly to the measurement of said at least one parameter of said sample; and (c) analyzing said spectroscopic measurements to determine a measurement of said at least one parameter of said sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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12. A method for measuring at least one parameter of a sample comprising the steps of:
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(a) illuminating said sample with light; (b) performing at least two spectroscopic measurements, wherein said at least two spectroscopic measurements are different members of the group consisting of; infrared absorbance, scattering, polarimetry, emission spectroscopy, photoacoustic spectroscopy, provided that said photoacoustic spectroscopy relates acoustic signal intensity directly to the measurement of said at least one parameter of said sample; and (c) analyzing said spectroscopic measurements to determine a measurement of said at least one parameter of said sample, further comprising the step of measuring at least one spatial dimension.
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13. A method for measuring at least one parameter of a sample comprising the steps of:
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(a) illuminating said sample with light; (b) performing at least two spectroscopic measurements, wherein said at least two spectroscopic measurements are different members of the group consisting of; infrared absorbance, scattering, polarimetry, emission spectroscopy, photoacoustic spectroscopy, provided that said photoacoustic spectroscopy relates acoustic signal intensity directly to the measurement of said at least one parameter of said sample; and (c) analyzing said spectroscopic measurements to determine a measurement of said at least one parameter of said sample, further comprising the step of measuring at least one temporal dimension.
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14. A method for measuring at least one parameter of a sample comprising the steps of:
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(a) illuminating said sample with light; (b) performing at least two spectroscopic measurements, wherein said at least two spectroscopic measurements are different members of the group consisting of; infrared absorbance, scattering, polarimetry, emission spectroscopy, photoacoustic spectroscopy, provided that said photoacoustic spectroscopy relates acoustic signal intensity directly to the measurement of said at least one parameter of said sample; and (c) analyzing said spectroscopic measurements to determine a measurement of said at least one parameter of said sample, further comprising the step of measuring at least one spatial dimension and at least one temporal dimension.
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15. A method for measuring at least one parameter of a sample comprising the steps of:
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(a) illuminating said sample with light; (b) performing at least two spectroscopic measurements, wherein said at least two spectroscopic measurements are different members of the group consisting of; infrared absorbance, scattering, polarimetry, emission spectroscopy, photoacoustic spectroscopy, provided that said photoacoustic spectroscopy relates acoustic signal intensity directly to the measurement of said at least one parameter of said sample; and (c) analyzing said spectroscopic measurements to determine a measurement of said at least one parameter of said sample, further comprising the step of removing an interference related to at least one spectral variable. - View Dependent Claims (16, 17)
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Specification