Reloadable auto-injector

• US 6,099,503 A
• Filed: 07/16/1998
• Issued: 08/08/2000
• Est. Priority Date: 04/18/1995
• Status: Expired due to Fees

• Current Assignee: Tebro Co.
• Original Assignee: Tebro Co.
• Inventors: Stradella, Giuseppe
• Primary Examiner(s): Stright, Jr., Ronald
• Assistant Examiner(s): Thissell, Jeremy
• Application Number:
  US08/930,189
• Time in Patent Office: 754 Days
• Field of Search: 604/218, 604/131, 604/134, 604/135, 604/136, 604/156, 604/157, 604/232, 604/207.9, 604/200, 604/211, 604/220, 604/224, 604/167
• US Class Current: 604/135
• CPC Class Codes: A61M 2005/2013 triggering of discharging means by contact of injector with patient body
• CPC Class Codes: A61M 2005/202 cocking means, e.g. to bias the main drive spring of an injector
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/3232 Semi-automatic needle retraction, i.e. in which triggering of the needle retraction requires a deliberate action by the user, e.g. manual release of spring-biased retraction means

Abstract

A reloadable auto-injector including a housing portion (1, 101) designed to receive a syringe (3), and a cover portion (2, 102), the auto-injector incorporating an injection device for automatically injecting the substance contained in the syringe, the injection device comprising: a piston (21) comprising a high portion (21b) and a low portion (21c), the low portion (21c) co-operating with the plunger of the syringe, the piston (21) being mounted to move, under the effect of an actuating spring (22) between a cocked position and an end-of-stroke position, the spring (22) being compressed in the cocked position; and trigger means (19) mounted to move between a blocking position in which they hold the piston (21) in its cocked position, and a releasing position in which they release the piston (21), the trigger means (19) being released from their blocking position by an actuating member; the auto-injector being characterized in that it further includes recocking means for recocking the automatic injection device, the recocking means being organized to be actuated by the operation of opening and/or closing said cover portion (2, 102) of the auto-injector.

Claims

1. A reloadable auto-injector comprising:

a syringe (3);

a housing portion (101) designed to receive the syringe (3);

a cover portion (102) which is removably attached to the housing portion; and

an injection device for automatically injecting a substance contained in the syringe,

said injection device comprising;

an actuating spring (22);

piston (21) comprising, in the vertical position of the auto-injector with the syringe (3) at the bottom, a high portion (21b) and a low portion (21c), said low portion (21c) co-operating with the plunger of the syringe, said piston (21) being mounted to move, under the effect of said spring (22) between a cocked position and an end-of-stroke position, said spring (22) being compressed in said cocked position; and

trigger means (19) mounted to move between a blocking position in which said trigger means holds the piston (21) in its cocked position, and a releasing position in which said trigger means releases the piston (21), said trigger means (19) being released from the blocking position by an actuating member;

wherein said auto-injector further includes recocking means for recocking the automatic injection device, said auto-injector being characterized in that said recocking means include a cocking member (150) that co-operates with at least one element (125) secured to the piston (21) during the operation of closing said cover portion (102) in order to bring said piston (21) from its end-of-stroke position to its cocked position, said piston (21) sliding inside a fixed sleeve (126) in the cover portion (102) which includes at least one axial slot (127) through which said at least one element (125) secured to the piston projects, in order to cooperate with said cocking member (150).

2. An auto-injector according to claim 1, in which a control sleeve (17) is provided mounted to move between a locking position in which it holds the trigger means (19) in the blocking position and thus the piston (21) in its cocked position and an unlocking position in which said trigger means (19) comes into the releasing position in which said trigger means releases the piston (21), said control sleeve (17) being urged towards its locking position by a spring (18), and being forced into its unlocking position by said actuating member.

3. An auto-injector according to claim 2, in which said trigger means (19) is resilient, and is provided with an interaction element (20) co-operating on its inside (20a) with the high portion (21b) of the piston (21), and on its outside (20b) with the control sleeves (17), said interaction element (20) holding said control sleeve (17) in the unlocking position when said resilient trigger means (19) is in the releasing position in which said resilient trigger means (19) releases the piston (21), said high portion (21b) of the piston (21) including a smaller-diameter portion (21a) which co-operates with said interaction element (20) when the piston (21) is in its cocked position, so that said resilient trigger means (19) takes up the blocking position in which said resilient trigger means (19) blocks said piston (21), thereby simultaneously releasing said control sleeve (17) which takes up its locking position by coming into engagement around said interaction element (20) of said resilient trigger means (19), thereby preventing said trigger means from returning to the releasing position in which said resilient trigger means releases the piston (21), the piston (21) then being blocked in its cocked position.

4. An auto-injector according to claim 3, in which the high portion (21b) of the piston (21) comprises a hollow tubular cylinder (23) having an outside surface which co-operates with said interaction element (20) of said resilient trigger means (19), that end of said tubular cylinder (23) which is closer to the syringe being provided with a frustoconical portion forming the smaller-diameter portion (21a) of the piston (21), said tubular cylinder (23) receiving an end of said spring (22) for actuating the piston (21), the other end of said spring (22) being secured to the housing of the auto-injector, so that, on opening and/or on closing the cover portion (2, 102) of the auto-injector, said tubular cylinder (23) of the piston (21) slides inside said trigger means (19), thereby entraining the spring (22) so that it is compressed, until the smaller-diameter portion (21a) of the piston (21) co-operates with the interaction element (20) to block the piston (21) in its cocked position.

5. An auto-injector according to claim 4, in which said trigger means (19) is implemented in the form of at least one resilient tab, and said interaction element (20) is implemented in the form of a lug disposed at the free end of said resilient tab (19), said at least one resilient tab (19) being brought into its piston-releasing position whenever said control sleeve (17) is forced into its unlocking position, and said at least one resilient tab (19) being brought into its piston-blocking position under the effect of the force exerted by said control sleeve (17), whenever said interaction element (20) co-operates with said smaller-diameter portion (21a) of said piston (21).

6. An auto-injector according to claim 4, in which said trigger means (19) comprises a split ring (20) which takes up the piston-releasing position when the control sleeve (17) is forced into its unlocking position, and which takes up the piston-blocking position when the split ring (20) co-operates with the smaller-diameter portion (21a) of said piston (21).

7. An auto-injector according to claim 1, including a cover portion (102) that can be interfitted with the housing portion (101) by being fitted thereon, the injection device, for automatically injecting the substance contained in the syringe, being disposed in the cover portion (102), said cover portion (102) with said housing portion (101) on being closed bringing said piston (21) into its cocked position and bringing said trigger means (19) into the blocking position.

8. An auto-injector according to claim 7, in which said cover portion (102), and said housing portion (101) are generally cylindrical in shape, said cover portion (102) interfitting axially with said housing portion (101), said housing portion (101) including said recocking means which comprises said cocking member (150) that co-operates with said at least one element (125) secured to the piston on axially fitting said cover portion (102) onto said housing portion (101) so as to bring said piston (21) into its cocked position.

9. An auto-injector according to claim 8, in which said cocking member (150) in the housing portion (101) comes into engagement around said fixed sleeve (126) on fitting the cover portion (102) onto the housing portion (101), thereby acting on said at least one element (125) secured to the piston to bring said piston (21) into its cocked position.

10. An auto-injector according to claim 9, in which said cocking member (150) is cylindrical and is provided with at least one axial slot (156) to enable said at least one element (125) secured to the piston to slide relative to said cocking member (150) while the piston (21) is being displaced from its cocked position to its end-of-stroke position, it being possible for said cocking member (150) to be rotated about said fixed sleeve (126) between a cocking angular position, in which it co-operates with said at least one element (125) secured to the piston to cock said piston (21), and a releasing angular position, in which said at least one axial slot (156) in the cocking member (150) is disposed facing said at least one element (125) secured to the piston.

11. An auto-injector according to claim 10, in which said housing portion (101) includes a tube (5) mounted to slide axially relative to said cocking member (150) between a rest position in which it covers up the needle (4) of the syringe (3) and an actuating position in which it acts as an actuating member for actuating the injection device, its end (5a) further from the syringe releasing the trigger means (19) for triggering the injection means, said tube (5) being provided with blocking means (160) which prevents the tube (5) from being displaced axially on said cocking member (150) when said cocking member is in its cocking angular position, and which enables said tube to be displaced axially thereon, when the cocking member (150) is in its releasing angular position.

12. An auto-injector according to claim 11, in which said blocking means on the tube (5) is implemented in the form of a resilient blocking finger (160) projecting outwards from said tube (5), said tube (5) further including an abutment finger (170) projecting outwards from said tube (5), said abutment finger allowing the housing portion (101) to be separated from the cover portion (102) only when the cocking member (150) is in its releasing angular position.

13. An auto-injector according to claim 12, in which the cover portion (102) includes a cylindrical outer casing (103) which interfits with the tube (5) of the housing portion (101) by fitting around said tube, the inside diameter of said outer casing (103) being approximately identical to the outside diameter of said tube (5), so that said casing being interfitted with said tube forces said resilient blocking finger (160) inwards so as to prevent the tube (5) from being displaced axially relative to said cocking member (150), the open end of the casing (103) being provided with an insertion notch (165) for inserting said projecting blocking tab (160), said notch (165) being disposed circumferentially such that the cocking member (150) is disposed in its cocking angular position when the cover portion (102) is interfitted with the housing portion (101), the inside surface of the casing (103) being provided with at least one axial groove (175) extending to said open end, said at least one groove (175) being offset angularly relative to said notch (165) so that said blocking tab (160) penetrates into said at least one axial groove (175) when said cocking member (150) is in its releasing angular position.

14. An auto-injector according to claim 13, in which the inside surface of said cocking member (150) in the vicinity of the end thereof that co-operates with said at least one element (125) secured to the piston is provided with a securing circumferential groove (155a) which is releasably snap-fastened, after the piston (21) has been cocked, on a complementary circumferential rib (155b) provided on the fixed sleeve (126), said rib and groove (155a, b) securing the housing portion (101) to the cover portion (102) in a releasable manner before and after the auto-injector is actuated, and fixing the housing portion (101) to the cover portion (102) in a non-releasable manner while the auto-injector is being actuated, the end (5a) of the tube (5) blocking said groove on said rib when said tube (5) is in its actuating position.

15. An auto-injector according to claim 1, in which a resilient member (30) is provided urging said syringe (3) slightly out of the housing portion (101) of the auto-injector when the cover portion (102) is open, thereby making said syringe easier to grasp.

16. A reloadable auto-injector comprising:

a syringe (3);

a housing portion (1,

     101) designed to receive the syringe (3);

a cover portion (2,

     102) which is removably attached to the housing portion; and

an injection device for automatically injecting a substance contained in the syringe,

said injection device comprising;

an actuating spring (22);

a piston (21) comprising a high portion (21b) and a low portion (21c), said low portion (21c) co-operating with the plunger of the syringe, said piston (21) being mounted to move, under the effect of said spring (22) between a cocked position and an end-of-stroke position, said spring (22) being compressed in said cocked position; and

a trigger mechanism (19) mounted to move between a blocking position in which said trigger mechanism holds the piston (21) in its cocked position, and a releasing position in which said trigger mechansim releases the piston (21), said trigger mechanism (19) being released from the blocking position by an actuating member;

wherein said auto-injector includes a recocking mechanism for recocking the automatic injection device, said recocking mechanism being organized to be actuated by an operation of opening and/or closing said cover portion (2,

     102) of the auto-injector.