Topically applicable O/W emulsions having high glycol content and at least one biologically active agent

  • US 6,106,848 A
  • Filed: 09/22/1997
  • Issued: 08/22/2000
  • Est. Priority Date: 09/20/1996
  • Status: Expired due to Term
First Claim
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1. A stable, topically applicable oil-in-water emulsion which is topically applicable to skin having intermediate viscosity, comprising (a) from 30% to 50% by weight relative to the total weight of said emulsion of at least one glycol, (b) at least one emulsifying agent comprising an anionic amphiphilic polymer, and (c) at least one biologically active agent, wherein said anionic amphiphilic polymer is present in an amount which in the absence of another emulsifying agent results in an emulsion having an intermediate viscosity, wherein said intermediate viscosity is a viscosity which ranges from 3 to 10 Pa·

  • s (3,000 to 10,000 centipoises), measured with a Brookfield viscometer LVDV II+paddle No. 4, at a speed of 30 revolutions/minutes for thirty seconds, and at a temperature of 25°

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