Treatment of cancer with thalidomide alone or in combination with other anti-cancer agents

  • US 6,140,346 A
  • Filed: 05/04/1998
  • Issued: 10/31/2000
  • Est. Priority Date: 06/06/1995
  • Status: Expired due to Term
First Claim
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1. An enhanced pharmaceutical composition suitable for treating neoplastic diseases sensitive to said enhanced composition comprising:

  • (a) an enhanced effective amount of thalidomide;

    (b) an effective amount of an alkylating agent selected from the group consisting of mechlorethamine, cyclophosphamide, ifosamide, melphalan, chlorambucil, busulfan, thiotepa, carmustine, lomustin, cisplatin, and carboplatin; and

    (c) a pharmaceutically acceptable inert carrier.

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