Recovery of signal void arising from field inhomogeneities in echo planar imaging

• US 6,157,192 A
• Filed: 02/08/1999
• Issued: 12/05/2000
• Est. Priority Date: 04/14/1998
• Status: Expired due to Term

• Current Assignee: Wisconsin Alumni Research Foundation (University of Wisconsin System)
• Original Assignee: Wisconsin Alumni Research Foundation (University of Wisconsin System)
• Inventors: Cordes, Dietmar
• Primary Examiner(s): ARANA, LOUIS M
• Application Number:
  US09/246,622
• Time in Patent Office: 666 Days
• Field of Search: 324/309, 324/307, 324/306, 324/314, 324/312, 324/300
• US Class Current: 324/309
• CPC Class Codes: G01R 33/54 Signal processing systems, e.g. using pulse sequences ; Generation or control of pulse sequences; Operator console
• CPC Class Codes: G01R 33/56527 due to chemical shift effects

Abstract

A prescan process is performed in which an EPI pulse sequence acquires a series of pilot images. Each pilot image is acquired with a different slice selection refocusing gradient and a rephasing map is produced which indicates the optimal refocusing gradient to be used for each pixel. The rephasing map is used to determine the optimal refocusing gradient amplitudes to use in a subsequent scan to reduce signal drop out caused by susceptibility gradients.

Claims

1. A method for producing an image of a subject with an MRI system, the steps comprising:

performing a prescan to produce a rephasing map, the prescan including;

a) acquiring a plurality of pilot images of the subject using an NMR pulse sequence that employs an imaging magnetic field gradient, and wherein the imaging magnetic field gradient is set to different values in the plurality of pilot image acquisitions;

b) calculating the optimal imaging magnetic field gradient value for each pixel in the pilot images by examining magnitudes of the corresponding pixels in the plurality of acquired pilot images;

c) storing the optimal imaging magnetic field gradient values at corresponding pixel locations in the rephasing map;

d) determining an imaging magnetic field gradient setting using the values stored in the rephasing map; and

e) performing a scan of the patient using the NMR pulse sequence with the imaging magnetic field gradient setting.

2. The method as recited in claim 1 in which step b) includes fitting the magnitudes of the corresponding pixels in the pilot images to a curve, and determining the peak of the curve.

3. The method as recited in claim 2 in which the peak of the curve indicates the optimal imaging magnetic field gradient value for a pixel and an optimal brightness value for the pixel, and the optimal brightness value is also stored in the rephasing map at the corresponding pixel location.

4. The method as recited in claim 1 in which determining an imaging magnetic field gradient setting in step d) includes producing a histogram from the rephasing map which is indicative of the number of pixels that have optimal brightness at each of a plurality of imaging magnetic field gradient values.

5. The method as recited in claim 4 in which the imaging magnetic field gradient setting is determined by displaying this histogram so that the setting can be manually selected.

6. The method as recited in claim 1 which includes storing at each pixel location in the rephasing map a pixel value indicative of pixel brightness at the corresponding stored optimal imaging magnetic field gradient value, and in which determining an imaging magnetic field gradient setting in step d) includes producing a cummulative brightness histogram from the rephasing map which is indicative of the sum of the stored pixel brightness values at rephasing map pixel locations that have optimal brightness at each of a plurality of imaging magnetic field gradient values.

7. The method as recited in claim 6 in which the imaging magnetic field gradient setting is determined by scanning the cummulative brightness histogram.

8. The method as recited in claim 7 in which the scanning is performed by sliding a window through the cummulative brightness histogram and locating the magnetic field gradient setting which provides the maximum cummulative brightness within the window.

9. The method as recited in claim 1 in which the NMR pulse sequence is an echo planar imaging sequence.

10. The method as recited in claim 9 in which the imaging magnetic field gradient is a slice select gradient.

11. The method as recited in claim 10 in which the imaging magnetic field gradient is a refocusing gradient.

12. The method as recited in claim 1 in which step d) includes determining a plurality of imaging magnetic field gradient settings and storing in the rephasing map segment numbers which indicate the settings for the pixel locations;

in which step e) includes performing a scan and reconstructing an image for each of said magnetic field gradient settings; and

f) combining each of the images into a single output image by selecting pixel values from each using the stored segment numbers.

13. The method as recited in claim 12 in which the NMR pulse sequence is an echo planar imaging pulse sequence and the imaging magnetic field gradient is a slice gradient.