Method and apparatus for dynamically tailoring biochemical based therapy programs in human
First Claim
1. A computer-implemented method for dynamically tailoring dosages of a biochemical compound administered to a human under a biochemical-based therapy program, comprising:
- administering a first plurality of stimulus exercises to said human over a period of time, said first plurality of stimulus exercises being administered to said human after at least one administration of said biochemical compound;
measuring responses from said first plurality of stimulus exercises to assess efficacy levels of said biochemical portion on said human as a function of time over said period of time; and
dynamically modulating said dosages of said biochemical compound responsive to said efficacy levels measured from said first plurality of stimulus exercises, said modulating results in a first dosage configured to be administered to said human at a first administration time and a second dosage different from said first dosage configured to be administered to said human at a second administration time, said second administration time being different from said first administration time.
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Abstract
The invention relates, in one embodiment to a computer-implemented method for dynamically tailoring dosages of a biochemical compound administered to a human under a biochemical-based therapy program. The method includes administering a first plurality of stimulus exercises to the human over a period of time. The first plurality of stimulus exercises are administered to the human after at least one administration of the biochemical compound. The method also includes measuring responses from the first plurality of stimulus exercises to assess efficacy levels of the biochemical portion on the human as a function of time over the period of time. The method further includes dynamically modulating the dosages of the biochemical compound responsive to the efficacy levels measured from the first plurality of stimulus exercises. The modulating results in a first dosage configured to be administered to the human at a first administration time and a second dosage different from the first dosage configured to be administered to the human at a second administration time different from the first administration time.
103 Citations
19 Claims
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1. A computer-implemented method for dynamically tailoring dosages of a biochemical compound administered to a human under a biochemical-based therapy program, comprising:
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administering a first plurality of stimulus exercises to said human over a period of time, said first plurality of stimulus exercises being administered to said human after at least one administration of said biochemical compound;
measuring responses from said first plurality of stimulus exercises to assess efficacy levels of said biochemical portion on said human as a function of time over said period of time; and
dynamically modulating said dosages of said biochemical compound responsive to said efficacy levels measured from said first plurality of stimulus exercises, said modulating results in a first dosage configured to be administered to said human at a first administration time and a second dosage different from said first dosage configured to be administered to said human at a second administration time, said second administration time being different from said first administration time. - View Dependent Claims (2, 3, 4, 5)
identifying, responsive to said efficacy levels measured from said first plurality of stimulus exercises, a third administration time different from said first and second administration time, said third administration time representing a time prior to said second administration time at which a given stimulus/response exercise may be administered to improve an efficacy of said biochemical compound in order to reduce said second dosage at said second administration time; and
administering, using said computer, said given stimulus/response exercise to said human at said third administration time to reduce said second dosage at said second administration time.
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3. The computer-implemented method of claim 1 further comprising:
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identifying, responsive to said efficacy levels measured from said first plurality of stimulus exercises, a third administration time different from said first and second administration time, said third administration time representing a time during said period of time at which a given stimulus/response exercise may be administered to reduce an undesirable side effect of said biochemical compound; and
administering, using said computer, said given stimulus/response exercise at said third administration time to said human.
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4. The computer-implemented method of claim 1 wherein said responses represent behavioral responses.
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5. The computer-implemented method claim 4 wherein said responses represent physiological responses.
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6. A computer-controlled apparatus for dynamically tailoring dosages of a biochemical compound administered to a human under a biochemical-based therapy program, comprising:
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means for administering a first plurality of stimulus exercises to said human over a period of time, said first plurality of stimulus exercises being administered to said human after at least one administration of said biochemical compound;
means for measuring responses from said first plurality of stimulus exercises to assess efficacy levels of said biochemical portion on said human as a function of time over said period of time; and
means for dynamically determining said dosages of said biochemical compound responsive to said efficacy levels measured from said first plurality of stimulus exercises, said dynamically determining results in tailored dosages responsive to said efficacy levels, including a first dosage configured to be administered to said human at a first administration time and a second dosage different from said first dosage configured to be administered to said human at a second administration time different from said first administration time. - View Dependent Claims (7, 8, 9, 10, 11, 12)
means for identifying, responsive to said efficacy levels measured from said first plurality of stimulus exercises, a third administration time different from said first and second administration time, said third administration time representing a time prior to said second administration time at which a given stimulus/response exercise may be administered to improve an efficacy of said biochemical compound in order to reduce said second dosage at said second administration time; and
means for administering, using said computer, said given stimulus/response exercise to said human at said third administration time to reduce said second dosage at said second administration time.
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8. The computer-controlled apparatus of claim 7 wherein said means for administering said given stimulus/response exercise is the same as said means for administering said first plurality of stimulus exercises.
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9. The computer-controlled apparatus of claim 6 further comprising:
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means for identifying, responsive to said efficacy levels measured from said first plurality of stimulus exercises, a third administration time different from said first and second administration time, said third administration time representing a time during said period of time at which a given stimulus/response exercise may be administered to reduce an undesirable side effect of said biochemical compound; and
means for administering, using said computer, said given stimulus/response exercise at said third administration time to said human.
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10. The computer-controlled apparatus of claim 9 wherein said means for administering said given stimulus/response exercise is the same as said means for administering said first plurality of stimulus exercises.
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11. The computer-controlled apparatus of claim 6 wherein said responses represent behavioral responses.
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12. The computer-controlled apparatus of claim 11 wherein said responses represent physiological responses.
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13. A computer-controlled apparatus for tailoring dosages of a biochemical compound administered to a human under a biochemical-based therapy program, comprising:
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a first transducer;
a computer configured to furnish first signals representative of a first plurality of stimulus exercises to said first transducer, thereby causing said transducer to deliver first stimuli representative of said first signals to said human over a period of time, said first stimuli being delivered after at least one administration of said biochemical compound to said human;
a second transducer coupled to said computer, said second transducer being configured to measure responses from said human and to furnish data representative of said responses as second signals to said computer, said responses representing reactions from said human responsive to said first stimuli after said at least one administration of said biochemical compound, said computer further being configured to ascertain from said responses efficacy levels of said biochemical compound as a function of time and to dynamically determine said dosages of said biochemical compound responsive to said efficacy levels ascertained from said responses, said computer further being configured to ascertain, responsive to said efficacy levels ascertained from said responses, said dosages which include a first dosage configured to be administered to said human at a first administration time and a second dosage different from said first dosage configured to be administered to said human at a second administration time different from said first administration time. - View Dependent Claims (14, 15, 16, 17, 18, 19)
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Specification