Process for making paroxetine

CAFC
  • US 6,172,233 B1
  • Filed: 01/15/1998
  • Issued: 01/09/2001
  • Est. Priority Date: 01/15/1997
  • Status: Expired due to Fees
First Claim
Patent Images

1. A process for industrial scale preparation of a compound of structure (2) in which R and R′

  • are independently selected from an alkyl, aryl, or arylalkyl group, X is fluorine which comprises reacting a compound of structure (4) with an organometallic compound having one or more X-substituted phenyl groups, in a suitable organic solvent, provided that the solvent is not wholly an ether solvent when the organometallic compound is a Grignard reagent.

View all claims
    ×
    ×

    Thank you for your feedback

    ×
    ×