Cardiopulmonary exercise testing apparatus and method

• US 6,174,289 B1
• Filed: 05/28/1999
• Issued: 01/16/2001
• Est. Priority Date: 05/28/1999
• Status: Expired due to Fees

• Current Assignee: Orca Diagnostics Corporation
• Original Assignee: Orca Diagnostics Corporation
• Inventors: Binder, Andrew S.
• Primary Examiner(s): O'Connor, Cary
• Assistant Examiner(s): CARTER, RYAN CHRISTOPHER
• Application Number:
  US09/322,320
• Time in Patent Office: 599 Days
• Field of Search: 73/10.1, 73/10.2, 73/10.3, 422/83, 600/532, 600/538, 600/520, 128/898
• US Class Current: 600/532
• CPC Class Codes: A61B 5/083 Measuring rate of metabolism by using breath test, e.g. measuring rate of oxygen consumption

Abstract

A gas analysis apparatus, and a method for calibrating it and for compensating measurement errors, are disclosed. This method and apparatus are particularly suited for use during a cardiopulmonary exercise test by a test subject. The oxygen and carbon dioxide concentrations of the subject'"'"'s breath are measured, and errors are compensated based on the results of previous calibration. These compensated measurements, as well as other physiological data monitored during the cardiopulmonary exercise test and quantities calculated from these measurements, are presented as a series of graphs in a logical order to enhance their diagnostic and prognostic value. A facemask and headstraps are adapted for use with the gas analysis apparatus. The facemask possesses a plurality of pins fitting into corresponding holes in the headstraps, and the headstraps possess quick-release attachment means to provide for quickly securing the face mask to or removing it from a subject.

Claims

1. A method for calibrating a gas analysis apparatus having one or more gas analyzers, comprising the steps of:

providing a compression bottle having at least one valve;

pressurizing the compression bottle with calibration gas of known composition;

opening the valve such that the calibration gas is abruptly expelled from the compression bottle with a flow rate and pressure profile over its outflow from the compression bottle similar to an exhaled human breath;

measuring the calibration gas with the one or more gas analyzers;

sensing the flow rate of the calibration gas out of the compression bottle; and

calculating a set of calibration constants; and

storing the calibration constants in a computing means.

2. The method of claim 1, wherein the measuring step further comprises the steps of measuring the time t₁ at which the calibration gas is introduced into the test station, measuring the time t₂ at which each gas analyzer first detects a change in gas concentration, and measuring the response time t₃ for each gas analyzer;

and wherein the calculating step further comprises the steps of determining the difference between time t₁ and each time t₂ to obtain the delay time D for each gas analyzer and determining the difference between time t₂ and each time t₃ to obtain the rise time R for each gas analyzer.

3. The method of claim 2, further comprising the steps after the measuring the time t₃ step of measuring steady-state gas concentration for a fixed period of time after outflow of the calibration gas from the compression bottle is substantially completed, individually averaging the gas concentration sensed by each gas analyzer in the last second of that fixed period of time, and storing that averaged gas concentration for each gas analyzer.

4. The method of claim 2, further comprising the steps before the opening step of purging the test station with ambient air, measuring steady-state gas concentration for a fixed period of time after purging is substantially completed, individually averaging the gas concentration sensed by each gas analyzer in the last second of that fixed period of time, and storing that averaged gas concentration for each gas analyzer.

5. The method of claim 2, further comprising the step after the measuring the time t₃ step of calculating the slope and offset for each gas analyzer with the equations:

6. The method of claim 5, wherein the measuring the time t₁ step occurs when the flow measurement means detects outflow from the compression bottle above a preset threshold level, wherein the measuring the time t₂ step occurs for each gas analyzer when the concentration of calibration gas within it rises above a preset threshold level, and further comprising the step after the calculating a slope and offset step of interpolating the actual values of t₁ and t₂ for each gas analyzer utilizing the corresponding calculated SlopeGas value for that gas analyzer.

7. The method of claim 1, further comprising the step before the opening step of purging the gas analysis apparatus with ambient air.