Radiotherapy machine including magnetic resonance imaging system

• US 6,198,957 B1
• Filed: 12/19/1997
• Issued: 03/06/2001
• Est. Priority Date: 12/19/1997
• Status: Expired due to Term

• Current Assignee: Varian Medical Systems Incorporated (Siemens AG)
• Original Assignee: Varian Incorporated (Agilent Technologies, Inc.), Varian Medical Systems Incorporated (Siemens AG)
• Inventors: Green, Michael Curzon
• Primary Examiner(s): Smith, Ruth S.
• Application Number:
  US08/994,851
• Time in Patent Office: 1,173 Days
• Field of Search: 378/63, 378/65, 600/411, 600/415, 600/421, 600/422, 600/1, 600/2
• US Class Current: 600/411
• CPC Class Codes: A61N 2005/1055 using magnetic resonance imaging [MRI]
• CPC Class Codes: A61N 2005/1063 maintaining the position when the patient is moved from an imaging to a therapy system
• CPC Class Codes: A61N 5/1042 with spatial modulation of the radiation beam within the treatment head
• CPC Class Codes: A61N 5/1049 for verifying the position of the patient with respect to the radiation beam
• CPC Class Codes: G01R 33/4808 Multimodal MR, e.g. MR combined with positron emission tomography [PET], MR combined with ultrasound or MR combined with computed tomography [CT]

Abstract

A radiotherapy machine beam treats a region of a subject while the region and volumes abutting the region are imaged by a magnetic resonance imaging system. The beam and an excitation coil assembly of the imaging system are arranged so the beam is not incident on the coil assembly and magnetic fields derived from the coil assembly do not interact with the beam. The excitation coil assembly includes two spaced winding segments for producing a main DC magnetic field; the segments are located on opposite sides of the region. In one embodiment, wherein the excitation coil assembly is mounted independently of movement of an axis of the beam, the winding segments have a common axis generally aligned with an axis about which the beam axis turns. A treatment couch for the subject fits within aligned central openings of the winding segments. The coil produces main magnetic field lines that extend generally in the same direction as the axis about which the beam turns. In other embodiments, the coil assembly moves with the beam axis and the treatment couch is between the coil segments. In one such embodiment, each winding segment includes a central opening (1) through which the beam axis extends; and (2) generally aligned with magnetic field lines established by and extending between the segments. In another such embodiment, the beam axis extends through a space between the segments, being generally orthogonal to magnetic field lines established by and extending between the segments.

Claims

1. In combination, a radiotherapy machine for deriving a radiotherapy bear for a region of a subject on a treatment couch, and a magnetic resonance imaging system for imaging the region and volumes abutting the region substantially simultaneously with the region being irradiated by the beam, the imaging system including a magnetic excitation coil assembly, the magnetic excitation coil assembly including first and second spaced segments on opposite sides of the region so an axis of the beam is between the first and second segments, the beam being arranged to be propagated along a beam axis, the beam axis being arranged to turn about another axis arranged to approximately extend through the region and approximately intersect the beam axis, the magnetic excitation coil assembly being mounted independently of movement of the beam axis.

2. The combination of claim 1, further including a treatment couch for the subject, the couch including a bed for holding the subject, the bed being movable for enabling the region to be positioned relative to the treatment beam axis.

3. The combination of claim 1, wherein the first and second segments have a common axis substantially coincident with the another axis, the first and second segments deriving main magnetic field lines that extend between the first and second segments in the same general direction as the common axis, a subject holding structure fitting between generally aligned central openings in the first and second segments along the common axis.

4. The combination of claim 1, wherein the first and second segments have a common axis substantially at right angles to the another axis, the first and second segments being arranged so a subject holding structure is between them, the segments producing a main magnetic field having flux lines extending generally in the direction of the common axis.

5. The combination of claim 1, wherein the beam axis and the first and second segments are arranged so the beam axis extends through a space between the first and second segments and generally at right angles to magnetic field flux lines extending between said first and second segments.

6. The combination of claim 1, further including a magnetic shield structure arranged to decouple magnetic fields originating in the radiotherapy machine from magnetic fields originating in the magnetic resonance imaging system.

7. The combination of claim 6, wherein the magnetic shield structure includes:

a coil surrounding sources of leakage magnetic fields originating in the radiotherapy machine, and a power source arranged to electrically excite the coil surrounding sources of leakage magnetic fields originating in the radiotherapy machine.

8. The combination of claim 6, wherein the shield structure includes:

a coil surrounding sources of leakage magnetic fields originating in the magnetic resonance imaging system, and a power source arranged to electrically excite the coil surrounding sources of magnetic fields originating in the magnetic resonance imaging system.

9. The combination of claim 8, wherein the shield structure includes:

a further coil surrounding sources of magnetic fields originating in the radiotherapy machine, and a power source arranged to electrically excite the coil surrounding sources of magnetic fields originating in the radiotherapy machine.

10. The combination of claim 1, wherein the beam is an X-ray beam.

11. The combination of claim 1, wherein the magnetic resonance imaging system includes a coil for deriving a main DC magnetic field, the coil being a non-superconducting wire wound water cooled coil.

12. The combination of claim 1, wherein the magnetic resonance imaging system includes a coil for deriving a main DC magnetic field, the coil being a superconductor.

13. The combination of claim 12, further including a liquid helium source for cooling the superconductor coil to a liquid helium temperature.

14. The combination of claim 13, wherein the coil is a high temperature superconducting coil that is superconducting at temperatures substantially higher than the temperature of liquid helium.

15. The combination of claim 12, wherein the coil is a high temperature superconducting coil that is superconducting at temperatures substantially higher than the temperature of liquid helium, further including a liquid helium source for cooling the superconductor coil to a liquid helium temperature.

16. The combination of claim 1, wherein the magnetic resonance imaging system includes a superconducting rf coil.

17. The combination of claim 1, further including a non-magnetic subject carrying structure, the structure being movable to a first region where the machine is located from a second region outside of the first region and the structure being arranged to be locked in said first region.

18. The combination of claim 17, further including a non-magnetic track at the machine for guiding movement of the structure.

19. The combination of claim 17, wherein the structure carries a coil assembly of the system.

20. The combination of claim 17, further including a plurality of said structures.

21. The combination of claim 1, further including a subject carrying structure, the magnetic excitation coil assembly being positioned to prevent facile access by the subject to and from the structure, a portion of the coil assembly being moveable relative to the structure when the coil assembly is not operative, the coil assembly being moveable to a position facilitating access by the subject to the structure.

22. The combination of claim 21 wherein a coil portion is mounted in a plane extending substantially at right angles to a subject receiving surface of the subject carrying structure, the coil portion being pivotable about an axis extending in the direction of the plane.

23. The combination of claim 21, further comprising motors arranged to control the relative position of the region and the beam by controlling the position of a subject carrying structure relative to an axis of the beam.

24. The combination of claim 1, further comprising a detector responsive to changes in an output of the magnetic resonance imaging system resulting from protons of atoms in the region precessing at a frequency determined by magnetic resonance excitation thereof and subject to de-execution under the influence of radiation products of said beam.

25. In combination, a radiotherapy machine for deriving a radiotherapy beam for a region of a subject on a treatment couch, and a magnetic resonance imaging system for imaging the reaction and volumes abutting the region substantially simultaneously with the region being irradiated by the beam, the imaging system including a magnetic excitation coil assembly, the magnetic excitation coil assembly including first and second spaced segments on opposite sides of the region so an axis of the beam is between the first and second segments, the beam being arrange to be propagated along a beam axis, the beam axis being arranged to turn about another axis arranged to approximately extend through the region and approximately intersect the beam axis, the magnetic excitation coil assembly being mounted so it moves with movement of the beam axis.

26. The combination of claim 25, wherein each of the first and second segments has a central opening including a common axis, the beam axis extending through the central openings of the first and second segments and being generally aligned with the magnetic field flux lines extending between said first and second segments.

27. In combination, a radiotherapy machine for deriving a radiotherapy electron beam for a region of a subject on a treatment couch, and a magnetic resonance imaging system, including a magnetic excitation coil assembly, for imaging the region and volumes abutting the region substantially simultaneously with the reaction being irradiated by the beam, the substantially simultaneous imaging and beam irradiation being each that the radiotherapy electron beam is arranged to be alternately applied to and removed from the region while a magnetic field from the coil assembly is respectively removed from and applied to the region.

28. In combination, a radiotherapy machine for deriving a radiotherapy electron beam for a region of a subject on a treatment couch, and a magnetic resonance imaging system for imaging the region and volumes abutting the region substantially simultaneously with the region being irradiated by the beam, the magnetic resonance imaging system including a superconductor coil for deriving a main DC magnetic field, a liquid helium source for cooling the superconductor coil to a liquid helium temperature, the substantially simultaneous imaging and beam irradiation being such that the radiotherapy electron beam is alternately applied to and removed from the region while current applied to the coil is arranged to be alternately turned off and on, respectively, and further including superconducting leads for applying current pulses to the coil, the superconducting leads being leads having a high superconducting temperature compared to the temperature of liquid helium.