Antigenic preparations and isolation of such preparations

  • US 6,210,685 B1
  • Filed: 06/17/1999
  • Issued: 04/03/2001
  • Est. Priority Date: 05/12/1984
  • Status: Expired due to Fees
First Claim
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1. Bordetella pertussis antigen useful for making a vaccine,wherein the antigen is characterized by (a) having a relative molecular weight of about 67,000 to 73,000 Daltons as determined by 12% (w/w) polyacrylamide gel electrophoresis and (b) binding to the monoclonal immunoglobulin secreted by the hybridoma deposited at the European Collection of Animal Cell Cultures, Porton Down, United Kingdom, under accession number 90010501, and wherein the antigen is in an amount effective to induce an immune reaction to said antigen in a patient.

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