Sensor with PVC cover membrane
First Claim
1. A sensor for the determination of the concentration and the detection of an enzyme substrate in a liquid sample, said sensor comprising:
- an enzyme layer comprising an enzyme capable of reacting with said enzyme substrate while producing a substance directly or indirectly detectable;
a detection device; and
a cover membrane covering the enzyme laver comprising a polymer permeable to said enzyme substrate wherein said polymer is a polyvinyl chloride copolymer prepared from vinyl chloride and a further monomer, said copolymer comprising hydrophilic groups.
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Abstract
The invention is concerned with a sensor for the determination of the concentration and the detection of an enzyme substrate in a liquid sample, the sensor comprising an enzyme capable of reacting with the enzyme substrate while producing a substance directly or indirectly detectable, a detection device for this substance and a cover membrane from a polymer permeable to the enzyme substrate, characterized in that the polymer is a polyvinyl chloride copolymer, i.e. a copolymer from vinyl chloride and a further monomer, the copolymer comprising hydrophilic groups. The sensor according to the invention may be provided as an optical sensor or as an amperometric sensor.
390 Citations
18 Claims
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1. A sensor for the determination of the concentration and the detection of an enzyme substrate in a liquid sample, said sensor comprising:
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an enzyme layer comprising an enzyme capable of reacting with said enzyme substrate while producing a substance directly or indirectly detectable;
a detection device; and
a cover membrane covering the enzyme laver comprising a polymer permeable to said enzyme substrate wherein said polymer is a polyvinyl chloride copolymer prepared from vinyl chloride and a further monomer, said copolymer comprising hydrophilic groups. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
providing a sensor in accordance with any one of claim 1, 2, 3, or 4;
contacting said sensor with said liquid sample and, determining and detecting the presence of said enzyme substrate in said sample with said detection device.
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14. A sensor for the determination of the concentration and detection of an enzyme substrate in a liquid sample, said sensor comprising:
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an enzyme layer comprising an enzyme capable of reacting with said enzyme substrate while producing a substance directly or indirectly detectable, a base electrode for detecting said substance; and
a cover membrane covering the enzyme layer comprising a polymer permeable to said enzyme substrate wherein said polymer is a polyvinyl chloride copolymer prepared from vinyl chloride and a firther monomer and wherein said copolymer comprises hydrophilic groups. - View Dependent Claims (15, 16)
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17. An optical sensor for the determination of the concentration and detection of an enzyme substrate in a liquid sample comprising:
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an enzyme layer comprising an enzyme capable of reacting with said enzyme substrate while producing a substance which reacts with an indicator;
an optical isolation layer;
a detection layer comprising said indicator; and
a cover membrane covering the enzyme layer comprising a polymer permeable to said enzyme substrate, said polymer comprising a copolymer prepared from vinyl chloride and a further monomer and wherein said copolymer comprises hydrophilic groups. - View Dependent Claims (18)
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Specification