Plasma concentrate and method of processing blood for same
DCFirst Claim
1. A plasma concentrate comprising one of platelets and platelet releasate, from 5 to 400 mg/ml of fibrinogen, and a physiologically acceptable carrier comprising water and physiologically acceptable inorganic and organic ions at a physiologically acceptable concentration, wherein the fibrinogen in the concentrate is not significantly denatured.
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Abstract
A plasma concentrate comprising one of platelets and platelet releasate and from 5 to 400 mg/ml of fibrinogen. The concentrate further includes a physiologically acceptable carrier comprising water and physiologically acceptable inorganic and organic ions at a physiologically acceptable concentration. The fibrinogen in the concentrate is not significantly denatured. A method for processing blood is further provided.
316 Citations
13 Claims
- 1. A plasma concentrate comprising one of platelets and platelet releasate, from 5 to 400 mg/ml of fibrinogen, and a physiologically acceptable carrier comprising water and physiologically acceptable inorganic and organic ions at a physiologically acceptable concentration, wherein the fibrinogen in the concentrate is not significantly denatured.
- 5. A plasma concentrate containing fibrinogen and one of platelets and platelet releasate for use as a wound healing agent, the fibrinogen in said concentrate not being significantly denatured.
- 7. A plasma concentrate comprising plasma and fibrinogen at a concentration of at least about 5 mg/ml.
- 10. A method for processing blood comprising centrifugally fractionating anticoagulated blood to remove red blood cells and produce plasma and concentrating the plasma to remove water to produce a plasma concentrate.
Specification