Three-dimensional reconstruction of intrabody organs

• US 6,226,542 B1
• Filed: 07/24/1998
• Issued: 05/01/2001
• Est. Priority Date: 07/24/1998
• Status: Expired due to Term

• Current Assignee: Biosense, Inc. (Cardinal Health, Inc.)
• Original Assignee: Biosense, Inc. (Cardinal Health, Inc.)
• Inventors: Reisfeld, Daniel
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): Lin, Jeoyuh
• Application Number:
  US09/122,137
• Time in Patent Office: 1,012 Days
• Field of Search: 364/413.06, 364/468.25, 600/371, 600/372, 600/373, 600/374, 600/377, 600/380, 600/381, 600/382, 600/383, 600/384, 600/407, 600/417, 600/420, 600/481, 600/508-526, 606/130
• US Class Current: 600/407
• CPC Class Codes: A61B 2562/17 Comprising radiolucent components
• CPC Class Codes: A61B 5/282 Holders for multiple electrodes for introduction into the body A61B5/287
• CPC Class Codes: A61B 5/341 Vectorcardiography [VCG]
• CPC Class Codes: G06T 17/20 Finite element generation, e.g. wire-frame surface description, tesselation
• CPC Class Codes: G06T 2210/41 Medical

Abstract

A method of reconstructing a map of a volume, including determining coordinates of a plurality of locations on a surface of the volume having a configuration, generating a grid of points defining a reconstruction surface in 3D space in proximity to the determined locations, for each of the points on the grid, defining a respective vector, dependent on a displacement between one or more of the points on the grid and one or more of the locations, and adjusting the reconstruction surface by moving substantially each of the points on the grid responsive to the respective vector, so that the reconstruction surface is deformed to resemble the configuration of the surface.

Claims

1. A method of constructing a map of a body organ having a volume comprising:

using a position sensor to come into contact with a body organ, said sensor indicating its position in the body;

determining coordinates of a plurality of locations of the sensor on the organ, said coordinates having a configuration on a surface of the volume;

generating a grid of points defining a reconstruction surface in 3D space in proximity to the determined locations;

for each of the points on the grid, defining a respective vector, dependent on a displacement between one or more of the points on the grid and one or more of the locations; and

adjusting the reconstruction surface by moving substantially each of the points on the grid responsive to the respective vector, so that the reconstruction surface is deformed to resemble the configuration of the surface.

2. A method according to claim 1, wherein generating the grid comprises acquiring an image of the volume and defining the reconstruction surface such that it resembles the image of the volume.

3. A method according to claim 1, wherein adjusting the surface comprises a rough adjustment stage and a flexible matching stage.

10. A method according to claim 1, wherein determining the coordinates comprises positioning a catheter tip at the plurality of locations.

11. A method according to claim 10, wherein positioning the catheter tip comprises positioning the catheter at a plurality of locations in a chamber of the heart.

12. A method according to claim 1, and comprising acquiring a signal indicative of a value of physiological activity at substantially each of the plurality of locations.

13. A method according to claim 1, wherein the volume is in motion, and wherein determining the coordinates comprises determining a correction factor responsive to the motion.

14. A method according to claim 13, wherein the motion comprises cyclic motion, and wherein determining the connection factor comprises determining a factor responsive to a cycle frequency of the motion.

15. A method according to claim 1, and comprising estimating a measure of the volume responsive to the reconstructed surface by choosing a point inside the grid and calculating the volumes of tetrahedrons defined by the chosen point and groups of three points on the grid which cover the entire grid surface.

4. A method of constructing a map of a body organ having a volume comprising:

determining coordinates of a plurality of locations having a configuration on a surface of the volume;

generating a grid of points defining a reconstruction surface in 3D space in proximity to the determined locations;

for each of the points on the grid, defining a respective vector, dependent on a displacement between one or more of the points on the grid and one or more of the locations; and

adjusting the reconstruction surface by moving substantially each of the points on the grid responsive to the respective vector, so that the reconstruction surface is deformed to resemble the configuration of the surface;

wherein adjusting the surface comprises a rough adjustment stage and a flexible matching stage; and

wherein the rough adjustment stage comprises moving each point on the grid toward a respective weighted center of mass of the determined locations, wherein locations closer to the point on the grid are given larger weight.

5. A method according to claim 4, wherein moving each point comprises defining, for each of the points on the grid, a respective rough adjustment vector which comprises a weighted sum of vectors from the point to each of the determined locations and moving the points a distance proportional to the respective vector.

6. A method of constructing a map of a body organ having a volume comprising:

determining coordinates of a plurality of locations having a configuration on a surface of the volume;

generating a grid of points defining a reconstruction surface in 3D space in proximity to the determined locations;

for each of the points on the grid, defining a respective vector, dependent on a displacement between one or more of the points on the grid and one or more of the locations; and

adjusting the reconstruction surface by moving substantially each of the points on the grid responsive to the respective vector, so that the reconstruction surface is deformed to resemble the configuration of the surface;

wherein adjusting the surface comprises a rough adjustment stage and a flexible matching stage; and

wherein the flexible matching stage comprises selecting a grid point to e associated respectively with each of the determined locations.

7. A method according to claim 6, wherein the flexible matching stage comprises moving the selected grid points toward their respective determined locations.

8. A method according to claim 7, wherein the flexible matching stage comprises defining a displacement function which comprises a weighted sum of vectors, each vector connecting a location and its associated point.

9. A method according to claim 7, wherein the flexible matching stage comprises moving the grid points according to the displacement function so as to smooth the surface.

16. Apparatus for constructing a map of a body organ having volume from coordinates of a plurality of determined locations having a configuration on a surface of the volume, comprising:

a position sensor for generating coordinates on the surface of the organ;

a processor, which receives the coordinates and generates a grid of points defining a reconstruction surface in 3D space in proximity to the determined locations, and

which defines a respective vector for each of the points on the grid, dependent on a displacement between one or more of the points on the grid and one or more of the locations, and

which adjusts the reconstruction surface by moving each of the points on the grid responsive to the respective vector, so that the reconstruction surface is deformed to resemble the configuration of the surface of the volume.

17. Apparatus as in claim 16, and comprising a display screen for displaying the adjusted surface.

18. Apparatus as in claim 16, and comprising an imaging device for acquiring an image of the volume, wherein the processor defines the grid initially such that it resembles the image of the volume.

19. Apparatus according to claim 16, and comprising a probe, which is brought into engagement with the surface to determine the locations thereon.

20. Apparatus according to claim 19, wherein the probe comprises said position sensor.

21. Apparatus according to claim 19, wherein the probe comprises a functional portion for acquiring a value of a physiological activity at the plurality of locations.

22. Apparatus according to claim 20, and comprising a reference catheter for registering the determined locations relative to a frame of reference associated with the volume.