Process for providing herbal medicants in cellulose derivative capsules

• US 6,238,696 B1
• Filed: 01/07/2000
• Issued: 05/29/2001
• Est. Priority Date: 01/07/2000
• Status: Expired due to Term

• Current Assignee: Gaia Herbs, Inc.
• Original Assignee: Gaia Herbs, Inc.
• Inventors: Wang, Xiping
• Primary Examiner(s): Lilling, Herbert J.
• Application Number:
  US09/478,880
• Time in Patent Office: 508 Days
• Field of Search: 424/452, 424/455, 424/456, 424/195.1
• US Class Current: 424/452
• CPC Class Codes: A61K 9/4816 Wall or shell material
• CPC Class Codes: A61K 9/4833 Encapsulating processes; Filling of capsules mechanical aspects A61J3/07

Abstract

The present invention relates to a process for providing non-lipid, liquid form herbal extracts in a vegetable gelatin, HPMC, or any other cellulose derivative capsule. The process includes extracting an herbal plant material with an alcohol to provide an aqueous alcoholic herbal extract. The aqueous alcoholic herbal extract is contacted with sufficient glycerin to maintain the extract preferably in solution, and at least dispersed in the mixture of glycerin and aqueous alcoholic herbal extract. Alcohol and water is removed form the mixture to provide a glycerin-based liquid or semi-solid herbal extract and having a moisture content of less than 10 percent by weight, and preferably less than 5 percent by weight. The herb extract is then encapsulated in a vegetable gelatin, HPMC, or any other cellulose derivative capsule.

Claims

1. A process for providing non-lipid, liquid form herbal extracts in cellulose derivative capsules, the process comprising the steps of:

(a) extracting an herbal plant material with an aqueous alcohol to provide a aqueous alcoholic herbal extract;

(b) adding sufficient glycerin to the aqueous alcohol herbal extract to maintain the herbal extract in solution or dispersed in the alcohol mixture;

(c) removing alcohol and water from the aqueous alcoholic herbal extract to provide glycerin base liquid or semi-soft form herbal extract having a moisture content of less than 10 percent by weight; and

(d) encapsulating the herb extract having a moisture content of less than 10 percent by weight in a cellulose derivative capsule.

2. The process of claim 1, whereby the herbal plant material is selected from the group consisting of kava kava, echinacea, St. John'"'"'s wort, valerian root, milk thistle seed, Siberian ginseng, nettle leaf, ginkgo, gotu kola, ginkgo/gotu kola supreme, astragalus, goldenseal, dong quai, ginseng, St. John'"'"'s wort supreme, echinacea/goldenseal supreme, bilberry, green tea, hawthorne, ginger, turmeric, black cohosh, cats claw, chamomile, dandelion, chaste tree berry, feverfew, garlic, horse chestnut, licorice, eyebright, yohimbe, astragalus supreme, valerian poppy supreme, and serenity elixir.

3. The process of claim 1, whereby bio-activity of the herbal extract is measured after step (a).

4. The process of claim 1, whereby bio-activity of the herbal extract is measured after step (c).

5. The process of claim 1, whereby the moisture content of the herbal extract is less than 5 percent by weight.

6. The process of claim 1, further including the step (e) of eliminating air in the cellulose derivative capsule by contacting the capsule with an inert gas.

7. A process for providing non-lipid, liquid form herbal extracts in vegetable gelatin or hydroxylalkylcellulose capsules, the process comprising the steps of:

(a) extracting an herbal plant material with an aqueous alcohol to provide a aqueous alcoholic herbal extract;

(b) adding sufficient glycerin to the aqueous alcohol herbal extract to maintain the herbal extract in solution or dispersed in the alcohol mixture;

(c) removing alcohol and water from the aqueous alcoholic herbal extract to provide glycerin base liquid or semi-soft form herbal extract having a moisture content of less than 10 percent by weight; and

(d) encapsulating the herb extract having a moisture content of less than 10 percent by weight in a vegetable gelatin, or hydroxyalkyl cellulose capsule.

8. The process of claim 7, whereby the hydroxylalkylcellulose is hydroxypropyl methylcellulose.

9. The process of claim 7, whereby the herbal plant material is selected from the group consisting of kava kava, echinacea, St. John'"'"'s wort, valerian root, milk thistle seed, Siberian ginseng, nettle leaf, ginkgo, gotu kola, ginkgo/gotu kola supreme, astragalus, goldenseal, dong quai, ginseng, St. John'"'"'s wort supreme, echinacea/goldenseal supreme, bilberry, green tea, hawthorne, ginger, turmeric, black cohosh, cats claw, chamomile, dandelion, chaste tree berry, feverfew, garlic, horse chestnut, licorice, eyebright, yohimbe, astragalus supreme, valerian poppy supreme, and serenity elixir.

10. The process of claim 7, whereby bio-activity of the herbal extract is measured after step (a).

11. The process of claim 7, whereby bio-activity of the herbal extract is measured after step (c).

12. The process of claim 7, whereby the moisture content of the herbal extract is less than 5 percent by weight.

13. The process of claim 7, further including the step (e) of eliminating air in the cellulose derivative capsule by contacting the capsule with an inert gas.

14. The process of claim 13, whereby the inert gas is nitrogen.