Cosmetic/pharmaceutical compositions comprising microorganism culture media

• US 6,242,229 B1
• Filed: 05/05/1998
• Issued: 06/05/2001
• Est. Priority Date: 05/05/1997
• Status: Active Grant

• Current Assignee: Societe L'Oreal S.A.
• Original Assignee: Societe L'Oreal S.A.
• Inventors: Aubert, Lucien, Breton, Lionel, Martin, Richard, Pineau, Nathalie
• Primary Examiner(s): Witz, Jean C.
• Application Number:
  US09/072,560
• Time in Patent Office: 1,127 Days
• Field of Search: 424/195.1, 424/93.4, 435/170, 435/261
• US Class Current: 435/170
• CPC Class Codes: A61K 35/74 Bacteria therapeutic use of a bacterial protein A61K38/00
• CPC Class Codes: A61K 8/99 from microorganisms other than algae or fungi, e.g. protozoa or bacteria
• CPC Class Codes: A61P 17/00 Drugs for dermatological disorders
• CPC Class Codes: A61P 17/10 Anti-acne agents
• CPC Class Codes: A61P 17/12 Keratolytics, e.g. wart or anti-corn preparations
• CPC Class Codes: A61P 17/14 for baldness or alopecia
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61P 37/00 Drugs for immunological or allergic disorders
• CPC Class Codes: A61P 37/04 Immunostimulants
• CPC Class Codes: A61Q 17/04 Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
• CPC Class Codes: A61Q 19/00 Preparations for care of the skin
• CPC Class Codes: A61Q 19/004 Aftersun preparations
• CPC Class Codes: A61Q 19/08 Anti-ageing preparations

Abstract

Cosmetic/pharmaceutical compositions, suitable for cosmetic applications and/or for treating a wide variety of mammalian disorders or disease states, comprise an effective active principle amount of a clarified and stabilized culture medium for at least one non-photosynthetic filamentous bacterium, advantageously belonging to the genera Beggiatoa, Vitreoscilla, Flexithrix or Leucothrix, formulated into a cosmetically/pharmaceutically acceptable vehicle, diluent or carrier therefor.

Claims

1. A method for reducing and/or delaying aging of the skin, comprising topically applying to the skin, scalp and/or mucous membranes of an individual in need of such treatment, an effective amount of the cosmetic/phannaceutical composition which comprises an effective active principle amount of a clarified and stabilized culture medium used to culture at least one non-photosynthetic filamentous bacterium, formulated into a cosmetically/pharmaceutically acceptable vehicle, diluent or carrier therefor.

3. The method of claim 1, wherein said non-photosynthetic filamentous bacterium belongs to the order Beggiatoales.

5. The method of claim 1 wherein said non-photosynthetic filamentous bacterium belongs to a genus selected from the group consisting of Beggiatoa, Vitreoscilla, Flexithrix and Leucothrix.

7. The method of claim 1 wherein said non-photosynthetic filamentous bacterium is a strain of Vitreoscilla filiformis.

9. The method of claim 1 wherein said stabilized and clarified culture medium comprises from 0.0001% to 30% by weight of the administered cosmetic/pharmaceutical composition.

11. The method of claim 1 wherein said culture medium comprises an acetate carbon source.

13. The method as defined by claim 1 wherein said culture medium comprises a saccharide carbon source.

15. The method of claim 1 wherein said bacterium containing culture medium has been cultured at a temperature ranging from 18°

to 40°

C.

2. A method for stimulating the immune system, comprising topically applying to the skin, scalp and/or mucous membranes of an individual in need of such treatment, an effective amount of the cosmetic/pharmaceutical composition which comprises an effective active principle amount of a clarified and stabilized culture medium used to culture at least one non-photosynthetic filamentous bacterium, formulated into a cosmetically/pharmaceutically acceptable vehicle, diluent or carrier therefor.

4. The method of claim 2, wherein said non-photosynthetic filamentous bacterium belongs to the order Beggiatoales.

6. The method of claim 2 wherein said non-photosynthetic filamentous bacterium belongs to a genus selected from the group consisting of Beggiatoa, Vitreoscilla, Flexithrix and Leucothrix.

8. The method of claim 2 wherein said non-photosynthetic filamentous bacterium is a strain of Vitreoscilla filiformis.

10. The method of claim 2 wherein said stabilized and clarified culture medium comprises from 0.0001% to 30% by weight of the administered cosmetic/pharmaceutical composition.

12. The method of claim 2 wherein said culture medium comprises an acetate carbon source.

14. The method as defined by claim 2 wherein said culture medium comprises a saccharide carbon source.

16. The method of claim 2 wherein said bacterium containing culture medium has been cultured at a temperature ranging from 18°

to 40°

C.