Implantable stimulation device and method for determining atrial autocapture using programmable PVARP

• US 6,243,606 B1
• Filed: 08/18/1999
• Issued: 06/05/2001
• Est. Priority Date: 05/14/1996
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Levine, Paul A., Mann, Brian M., Endaya, Melinda
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US09/376,821
• Time in Patent Office: 657 Days
• Field of Search: 607/14, 607/28, 607/27, 600/515, 600/518
• US Class Current: 607/14
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold
• CPC Class Codes: A61N 1/3714 Atrial capture

Abstract

A pacemaker programmer and diagnostic system retrieves information stored within a pacemaker and analyzes the retrieved data in real time. The stored information can be retrieved by means of a telemetry communication link. The pacemaker automatically lengthens a post-ventricular atrial refractory period (PVARP). The pacemaker determines atrial capture by generating atrial stimulation pulses while maintaining the ventricular stimulation pulse amplitude at a level known to ensure ventricular capture, and by detecting loss of atrial capture. In response to loss of atrial capture, a processor automatically records the atrial capture threshold, and restores the PVARP and the atrial pulse amplitude to their pre-test values. A pulse generator delivers a backup atrial stimulation pulse concurrently with a ventricular stimulation pulse, and the processor automatically initiates a premature ventricular contraction (PVC) response to reduce the possibility of a retrograde P-wave initiating a pacemaker-mediated tachycardia (PMT).

Claims

1. A method of determining an atrial capture threshold in a stimulation device having a programmable post-ventricular atrial refractory period (PVARP), comprising:

generating an atrial stimulation pulse while maintaining ventricular stimulation pulse amplitude at a level known to ensure ventricular capture;

detecting loss of capture of the atrial stimulation pulse; and

in response to the loss of capture, automatically adjusting the post-ventricular refractory period (PVARP).

2. The method, as recited in claim 1, further including retrieving historical data from the stimulation device to estimate an atrial stimulation pulse amplitude at which loss of capture would occur.

3. The method, as recited in claim 2, wherein generating the atrial stimulation pulse includes determining an initial atrial stimulation pulse amplitude based on the atrial stimulation pulse amplitude estimated from the historical data.

4. The method, as recited in claim 3, wherein generating the atrial stimulation pulse includes setting the amplitude of the initial atrial stimulation pulse to a predetermined level above the estimated atrial stimulation pulse amplitude.

5. The method, as recited in claim 4, wherein setting the amplitude of the initial atrial stimulation pulse includes increasing the amplitude of the initial atrial stimulation pulse a step immediately above the estimated atrial stimulation pulse amplitude.

6. The method, as recited in claim 1, wherein adjusting the PVARP includes lengthening the PVARP.

7. The method, as recited in claim 6, wherein lengthening the PVARP includes increasing the PVARP to a programmed value.

8. The method, as recited in claim 1, wherein the stimulation device has an adjustable AV delay;

and

further including lengthening the AV delay prior to detecting loss of capture.

9. The method, as recited in claim 8, further including restoring the AV delay to a base value in response to loss of capture.

10. The method, as recited in claim 9, wherein if loss of capture is detected, setting a capture threshold as the atrial stimulation pulse amplitude at which loss of capture occurs.

11. The method, as recited in claim 10, further including setting the atrial stimulation pulse amplitude to a value above the capture threshold.

12. The method, as recited in claim 11, further including restoring the PVARP to a base value in response to loss of capture.

13. The method, as recited in claim 1, further including, in response to loss of capture, delivering a backup atrial stimulation pulse concurrent with a ventricular stimulation pulse.

14. The method, as recited in claim 1, further including, in response to loss of capture:

restoring the atrial stimulation pulse to a base amplitude; and

delivering an atrial stimulation pulse at the base amplitude, in a subsequent cardiac cycle.

15. The method, as recited in claim 14, further including automatically initiating a premature ventricular contraction (PVC) response to reduce the occurrence of a retrograde P-wave from starting a pacemaker-mediated tachycardia.

16. The method, as recited in claim 14, further including shortening an AV delay in order to reduce the possibility of a retrograde P-wave initiating a pacemaker-mediated tachycardia.

17. The method, as recited in claim 1, wherein detecting loss of capture includes using an ECG signal.

18. The method, as recited in claim 17, wherein detecting loss of capture further includes generating a marker channel indicative of stimulation pulse timing and comparing the marker channel to the ECG signal.

19. An implantable stimulation device for determining an atrial capture threshold and having a post-ventricular atrial refractory period (PVARP), comprising:

a pulse generator for generating an atrial stimulation pulse while maintaining ventricular stimulation pulse amplitude at a level known to ensure ventricular capture;

detection circuitry coupled to the pulse generator for detecting loss of capture of the atrial stimulation pulse; and

a processor, coupled to the pulse generator and the detection circuitry, in response to loss of atrial capture, for automatically adjusting the PVARP in response to loss of capture.

20. The stimulation device, as recited in claim 19, further including memory for storing historical data;

wherein the processor retrieves the historical data; and

wherein based on the historical data, the processor estimates an atrial stimulation pulse amplitude at which loss of capture would occur, and sets the amplitude of the initial atrial stimulation pulse to a predetermined level above the estimated atrial stimulation pulse amplitude.

21. The stimulation device, as recited in claim 19, having an adjustable AV delay, and further including a timing circuitry;

wherein the timing circuit lengthens the AV delay prior to the detection circuitry detecting loss of capture; and

wherein the timing circuit restores the AV delay to a base value in response to loss of capture.

22. The stimulation device, as recited in claim 19, wherein if the detection circuitry does not detect loss of capture, a timing circuitry decreases an atrial stimulation pulse amplitude until loss of capture is detected.

23. The stimulation device, as recited in claim 19, wherein the processor includes control circuitry;

wherein if loss of capture is detected, the control circuitry sets a capture threshold as the atrial stimulation pulse amplitude at which loss of capture occurs; and

wherein the control circuitry sets the atrial stimulation pulse amplitude to a value above the capture threshold.

24. The stimulation device, as recited in claim 19, wherein a timing circuitry restores the PVARP to a base value in response to loss of capture.

25. The stimulation device, as recited in claim 19, wherein the stimulation device is a dual-chamber implantable cardiac pacing device.

26. The stimulation device, as recited in claim 19, wherein the pulse generator delivers a backup atrial stimulation pulse concurrent with a ventricular stimulation pulse, in response to loss of capture.

27. The stimulation device, as recited in claim 19, wherein the processor restores the atrial stimulation pulse to a base amplitude, and delivers an atrial stimulation pulse at the base amplitude, in a subsequent cardiac cycle.

28. The stimulation device, as recited in claim 19, wherein the processor automatically initiates a premature ventricular contraction (PVC) response to reduce the occurrence of a retrograde P-wave from starting a pacemaker-mediated tachycardia.

29. The stimulation device, as recited in claim 22, wherein the timing circuitry shortens an AV delay in order to reduce the possibility of a retrograde P-wave initiating a pacemaker-mediated tachycardia.

30. An implantable stimulation device for determining an atrial capture threshold and having a post-ventricular atrial refractory period (PVARP), comprising:

a pulse generator for generating an atrial stimulation pulse while maintaining ventricular stimulation pulse amplitude at a level known to ensure ventricular capture;

detection means coupled to the pulse generator, for detecting loss of capture of the atrial stimulation pulse; and

processing means, coupled to the pulse generator and the detection means, in response to loss of atrial capture, for automatically adjusting the PVARP in response to loss of capture.

31. The stimulation device, as recited in claim 30, wherein, in response to loss of capture, the pulse generator delivers a backup atrial stimulation pulse concurrent with a ventricular stimulation pulse.

32. The stimulation device, as recited in claim 31, wherein the processor automatically initiates a premature ventricular contraction (PVC) response to reduce the occurrence of a retrograde P-wave from starting a pacemaker-mediated tachycardia.