Liquid crystal thermometer
First Claim
1. A liquid crystal thermometer adapted for clinical applications in continuously measuring the body temperature of a patient, the thermometer comprising:
- a film layer and flexible substrate laminate having a thickness, a first side, and a second side, the first side having at least one cavity formed therein;
a liquid crystal composition disposed in the at least one cavity and occupying at least about 50% of the volume of the at least one cavity, wherein the liquid crystal composition generates a first colored state at ambient temperature and a second colored state at a temperature of a site on the patient'"'"'s body to be measured;
a cover layer sealed on the first side to form an enclosure containing the liquid crystal composition in the at least one cavity to define at least one sensor dot;
wherein the at least one sensor dot automatically responds continuously to changes in temperature at the site without having to reset the thermometer; and
wherein the cavity diameter is about 1.20 mm and about 1.3 mm, the cavity depth is about 0.17 mm of greater, and the thickness of the film layer and flexible substrate laminate is about 0.25 mm or less, so that the continuous measurement of the core body temperature of the patient may be made and the measurement automatically updates.
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Accused Products
Abstract
A self-updating temperature thermometer is disclosed that is capable of generating a real-time signal of core body temperature. The thermometer comprises a double-sided flexible substrate, having a first side and a second side. The first side has a plurality of cavities, and a liquid crystal composition in these cavities to define a plurality of sensor dots. A cover layer is disposed on the first side, and a pressure-sensitive adhesive is disposed on the second side of the substrate. The sensor surface area to substrate thickness is maximized using the structural features of this invention, thereby providing a thermometer exhibiting unexpectedly good results in that it is capable of generating a continuous temperature measurement that is automatically updated with changes in body temperature.
79 Citations
36 Claims
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1. A liquid crystal thermometer adapted for clinical applications in continuously measuring the body temperature of a patient, the thermometer comprising:
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a film layer and flexible substrate laminate having a thickness, a first side, and a second side, the first side having at least one cavity formed therein;
a liquid crystal composition disposed in the at least one cavity and occupying at least about 50% of the volume of the at least one cavity, wherein the liquid crystal composition generates a first colored state at ambient temperature and a second colored state at a temperature of a site on the patient'"'"'s body to be measured;
a cover layer sealed on the first side to form an enclosure containing the liquid crystal composition in the at least one cavity to define at least one sensor dot;
wherein the at least one sensor dot automatically responds continuously to changes in temperature at the site without having to reset the thermometer; and
wherein the cavity diameter is about 1.20 mm and about 1.3 mm, the cavity depth is about 0.17 mm of greater, and the thickness of the film layer and flexible substrate laminate is about 0.25 mm or less, so that the continuous measurement of the core body temperature of the patient may be made and the measurement automatically updates. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10)
providing the thermometer of claim 1;
applying the thermometer to a body area having a fixed relationship to the core temperature of the patient;
leaving the thermometer in place on the body area for a period of up to forty-eight hours;
monitoring the temperature of the patient by observing the response of the at least one sensor dot to changes in temperature at the body area.
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10. The method of claim 9 in which the body area comprises the axilla.
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11. A liquid crystal thermometer adapted for clinical applications in measuring the body temperature of a patient, the thermometer comprising:
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a film layer and flexible substrate laminate having a thickness, a first side, and a second side, the first side having a plurality of cavities formed therein and arranged in a matrix;
a plurality of liquid crystal composition, with one of the plurality of liquid crystal compositions being disposed in each one of the plurality of cavities and occupying at least about 50% of the volume of each one of the plurality of cavities, wherein each one of the liquid crystal composition generates a first colored state at ambient temperature and a second colored state at a temperature to be measured;
a cover layer sealed on the first side to form an enclosure containing the plurality of liquid crystal composition in the plurality of cavities to define a plurality of sensor dot;
a pressure-sensitive adhesive disposed on the second side of the film layer and flexible substrate laminate;
wherein the substrate has a thickness that is sufficiently small that the second side of the film layer and flexible substrate laminate will adhere to an area of the patient'"'"'s body representing the core body temperature and the plurality of sensor dots will automatically respond to changes in temperature in the body of the patient so that a continuous measurement of the core body temperature may be made without having to reset the thermometer; and
wherein the cavity diameter is about 1.20 mm and about 1.3 mm, the cavity depth is about 0.17 mm of greater, and the thickness of the film layer and flexible substrate laminate is about 0.25 mm or less, so that the continuous measurement of the core body temperature of the patient may be made and the measurement automatically updates. - View Dependent Claims (12, 13, 14, 15, 16, 17, 18, 19, 20)
providing the thermometer of claim 11;
applying the thermometer to a body area having a fixed relationship to the core temperature of the patient;
leaving the thermometer in place on the body for a period of up to 48 hours;
monitoring the temperature of the patient by observing the response of the plurality of sensor dots to changes in temperature at the body area.
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21. A liquid crystal thermometer adapted for clinical applications in continuously measuring the body temperature of a patient, the thermometer comprising:
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a film layer and flexible substrate laminate having a thickness, a first side, and a second side, the first side having at least one cavity formed therein;
a liquid crystal composition disposed in the at least one cavity and occupying at least about 50% of the volume of the at least one cavity, wherein the liquid crystal composition generates a first colored state at ambient temperature and a second colored state at a temperature of a site on the patient'"'"'s body to be measured;
a cover layer sealed on the first side to form an enclosure containing the liquid crystal composition in the at least one cavity to define at least one sensor dot; and
wherein the cavity diameter is about five times of greater than the thickness of the film layer and flexible substrate laminate, the depth of the cavity is about 70% of grater than the thickness of the film layer and flexible substrate laminate, so that the body temperature of a patient is measured automatically and continuously without having to reset the thermometer. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28)
providing the thermometer of claim 21;
applying the thermometer to a body area having a fixed relationship to the core temperature of the patient;
leaving the thermometer in place on the body for a period of up to 48 hours;
monitoring the temperature of the patient by observing the response of the at least one sensor dot to changes in temperature at the body area.
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29. A liquid crystal thermometer adapted for clinical applications in continuously measuring the body temperature of a patient, the thermometer comprising:
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a film layer and flexible substrate laminate having a thickness, a first side, and a second side, the first side having a plurality of cavities formed therein and arranged in a matrix;
a plurality of liquid crystal composition, with one of the plurality of liquid crystal compositions being disposed in each one of the plurality of cavities and occupying at least about 50% of the volume of each one of the plurality of cavities, wherein each one of the liquid crystal composition generates a first colored state at ambient temperature and a second colored state at a temperature to be measured;
a cover layer sealed on the first side to form an enclosure containing the plurality of liquid crystal composition in the plurality of cavities to define a plurality of sensor dot;
a pressure-sensitive adhesive disposed on the second side of the film layer and flexible substrate laminate; and
wherein the cavity diameter is about five times of greater than the thickness of the film layer and flexible substrate laminate, the depth of the cavity is about 70% of grater than the thickness of the film layer and flexible substrate laminate, so that the body temperature of a patient is measured automatically and continuously without having to reset the thermometer. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36)
providing the thermometer of claim 29;
applying the thermometer to a body area having a fixed relationship to the core temperature of the patient;
leaving the thermometer in place on the body for a period of up to 48 hours;
monitoring the temperature of the patient by observing the response of the plurality of sensor dots to changes in temperature at the body area.
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Specification