Xylitol nose spray

• US 6,258,372 B1
• Filed: 03/03/2000
• Issued: 07/10/2001
• Est. Priority Date: 03/24/1998
• Status: Expired due to Term

• Current Assignee: Xlear
• Original Assignee: Alonzo H. Jones
• Inventors: Jones, Alonzo H.
• Primary Examiner(s): Weddington, Kevin E.
• Application Number:
  US09/517,929
• Time in Patent Office: 494 Days
• Field of Search: 424/434, 514/23
• US Class Current: 424/434
• CPC Class Codes: A61K 31/047 having two or more hydroxy groups, e.g. sorbitol
• CPC Class Codes: A61K 31/7004 Monosaccharides having only carbon, hydrogen and oxygen atoms
• CPC Class Codes: A61K 9/0043 Nose
• CPC Class Codes: A61P 11/02 Nasal agents, e.g. decongestants
• CPC Class Codes: A61P 11/06 Antiasthmatics
• CPC Class Codes: A61P 27/16 Otologicals
• CPC Class Codes: A61P 29/00 Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
• CPC Class Codes: A61P 31/04 Antibacterial agents

Abstract

Nasopharyngeal congestion, irritation, and inflammation and associated upper respiratory infections such a otitis media, sinusitis are adjunctivly treated and prevented by nasal application of xylitol/xylose in a saline solution.

Claims

1. An aqueous solution for nasal use comprising by weight 100 parts of water, between 65 parts to 1 part of xylitol/xylose, and between 0.95 and 0.45 parts of sodium chloride.

2. The solution as defined in claim 1 with the addition of effective amounts of benzalkonium chloride and phenylcarbinol as preservatives.

3. The solution as defined in claim 2 comprising:

100 parts of water, 10 parts of xylitol/xylose, and 0.65 parts of sodium chloride.

4. The solution as defined in claim 1 wherein the solution is hypotonic and further comprising 100 parts of water, 10 parts of xylitol/xylose, 0.65 parts of sodium chloride and effective amounts of benzalkonium chloride and phenylcarbinol as preservatives.

5. An aqueous solution for nasal use comprising by weight 100 parts of water and between 65 parts to 1 part of xylitol/xylose.

6. The solution as defined in claim 5 with the addition of effective amounts of benzalkonium chloride and phenylcarbinol as preservatives.

7. The solution as defined in claim 6 comprising:

100 parts of water and 10 parts of xylitol/xylose.

8. The solution as defined in claim 5 wherein the solution is hypotonic and further comprising 100 parts of water, 10 parts of xylitol/xylose, and effective amounts of benzalkonium chloride and phenylcarbinol as preservatives.

9. A nasal spray comprising by weight 100 parts of water, between one part and 65 parts of xylitol/xylose, and between 0.45 and 0.95 parts of sodium chloride in a conventional spray bottle.

10. The product as defined in claim 9 wherein said solution is hypotonic and further comprising 100 parts of water 10 parts of xylitol/xylose, and 0.65 parts of sodium chloride and effective amounts of benzalkonium chloride and phenylcarbinol as preservatives.

11. A preparation for nasal use comprising an effective amount of xylitol/xylose in a suitable gel.