Apparatus and methods for treating motor control and somatosensory perception deficits

• US 6,267,733 B1
• Filed: 08/13/1999
• Issued: 07/31/2001
• Est. Priority Date: 11/14/1997
• Status: Expired due to Term

• Current Assignee: Scientific Learning Corp. (Carnegie Learning, Inc.), Regents of the University of California (University of California)
• Original Assignee: Scientific Learning Corp. (Carnegie Learning, Inc.), Regents of the University of California (University of California)
• Inventors: Byl, Nancy, Calhoun, Barbara M., Jenkins, William M., Peterson, Bret E., Merzenich, Michael Mathias, Nagarajan, Srikantan
• Primary Examiner(s): O'Connor, Cary
• Assistant Examiner(s): MARMOR II, CHARLES ALAN
• Application Number:
  US09/374,227
• Time in Patent Office: 718 Days
• Field of Search: 600/552, 600/553, 600/555, 600/557, 600/587, 600/594, 600/595, 434/112, 434/113, 434/114, 128/898
• US Class Current: 600/587
• CPC Class Codes: A61B 5/0053 by applying pressure, e.g. compression, indentation, palpation, grasping, gauging
• CPC Class Codes: A61B 5/0057 by applying motion other than vibrations, e.g. rolling, rubbing, applying a torque, tribometry
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance
• CPC Class Codes: A61B 5/4824 Touch or pain perception evaluation A61B5/4821 takes precedence
• CPC Class Codes: A61B 5/4827 assessing touch sensitivity, e.g. for evaluation of pain threshold

Abstract

The present invention describes computer-implemented methods and apparatus for treating motor control and somatosensory perception deficits. The motor control and somatosensory perception deficits may have their genesis in a wide variety of issues ranging from injury, disease, or a gradual degradation of motor control over time due to repetitive strain, for example. By administering a computer-implemented training regime directed to improve sensory feedback and motor control, abnormal motor control and somatosensory perception may be substantially improved. The computer-implemented training regime includes somatosensory perception and motor control exercises which may be flexibly administered. Several training apparatus are described for implementing the somatosensory perception and motor control exercises. The training apparatus described herein are capable of driving improvements in temporal, spatial and intensity resolution of somatosensory feedback. In addition, the apparatus allow the training to be monitored and adapted on a quantitative basis as treatment proceeds. Advantageously, this provides a more accurate and effective training tool for treating motor control deficits. Further, the computer-implemented methods and apparatus allow treatment to be administered in the convenience of the person'"'"'s own home and on a daily basis.

Claims

1. A computer-implemented method for improving one of a somatosensory perception and a motor control deficit for a human subject using a computer-implemented training apparatus, said computer-implemented method comprising:

(a) administering, using said computer-implemented training apparatus, a training regime including one of a set of somatosensory and motor control exercises to said human subject, said training regime having sufficient intensity to affect a lasting improvement in said one of a somatosensory perception and motor control deficit within said human subject;

(b) obtaining, using said computer-implemented training apparatus, a performance response of said human subject responsive to said one of a set of somatosensory and motor control exercises;

(c) altering, using said computer-implemented training apparatus, one or more parameters pertaining to said one of a set of somatosensory and motor control exercises, wherein said altering of said one or more parameters is performed responsive to said performance response and is configured to facilitate improving said one of a somatosensory perception and a motor control deficit within said human subject; and

(d) repeating at least (a) for a sufficient number of repetitions to affect said lasting improvement in said one of a somatosensory perception and a motor control deficit.

2. The computer-implemented method of claim 1 wherein said altering said one or more parameters is performed responsive to quantitative information ascertained from said performance response.

3. The computer-implemented method of claim 1 wherein said altering said one or more parameters includes altering the spatial, temporal or intensity parameters of said one of a set of somatosensory and motor control exercises.

4. The computer-implemented method of claim 1 wherein said one of a somatosensory perception and a motor control deficit is a motor control deficit.

5. The computer-implemented method of claim 1 wherein said one of a somatosensory perception and a motor control deficit is caused by stroke.

6. The computer-implemented method of claim 1 wherein said performance response is based on at least one of tactile perception, kinesthetic perception and proprioception.

7. The computer-implemented method of claim 1 wherein said altering said one or more parameters includes one of using the same one of a set of somatosensory and motor control exercises in said training regime with more difficult parameters and using at least one different somatosensory and motor control exercise in said one of a set of somatosensory and motor control exercises.

8. The computer-implemented method of claim 1 wherein said one of a set of somatosensory and motor control exercises includes an exercise involving one or more of the human subject'"'"'s fingers.

9. The computer-implemented method of claim 1 wherein said one of a somatosensory perception and a motor control deficit is a somatosensory perception deficit.

10. The computer-implemented method of claim 1 wherein said administering said training regime includes administering at least 100 somatosensory and motor control exercises in a day.

11. The computer-implemented method of claim 1 wherein said one of a set of somatosensory and motor control exercises is directed to elicit a high level of engagement from said human subject.

12. The computer-implemented method of claim 11 wherein said one of a set of somatosensory and motor control exercises includes computer-implemented graphics.

13. The computer-implemented method of claim 1 wherein said altering of said one of a set of somatosensory and motor control exercises is directed to present a continual challenge.

14. The computer-implemented method of claim 1 wherein said computer-implemented training apparatus includes a somatosensory and motor control training device for improving one of a somatosensory perception deficit and a motor control deficit for a human subject, said device comprising:

a plurality of force sensors situated in proximity such that each may receive one or more fingers from a hand of said human subject, said plurality of force sensors capable of force feedback from said one or more fingers; and

a processor in electrical communication with said plurality of force sensors.

15. The computer-implemented method of claim 14 wherein said plurality of force sensors have a variable compliance.

16. The computer-implemented method of claim 14 wherein said processor is included in a computer.

17. The computer-implemented method of claim 16 wherein said computer is used for assessment of said one of a somatosensory perception deficit and motor control deficit.

18. The computer-implemented method of claim 14 further including a strain relief material or a textured material attached to said plurality of force sensors.

19. The computer-implemented method of claim 1 wherein said computer-implemented training apparatus includes a somatosensory and motor control training device for improving one of a somatosensory perception deficit and a motor control deficit for a human subject, said device comprising:

a set of pins, wherein each pin is capable of independent linear displacement;

a set of actuators coupled to said set of pins; and

a processor in electrical communication with said set of actuators.

20. The computer-implemented method of claim 19 further including a latching mechanism coupled to said set of actuators.

21. The computer-implemented method of claim 19 wherein said set of pins is arranged in a substantially rectangular array.

22. The computer-implemented method of claim 19 wherein said processor is included in a computer.

23. The computer-implemented method of claim 22 wherein said computer is used for assessment of said one of a somatosensory perception deficit and motor control deficit.

24. The computer-implemented method of claim 22 wherein said one of a set of somatosensory and motor control exercises is used to train tactile perception by said human subject.

25. The computer-implemented method of claim 1 wherein said computer-implemented training apparatus includes a somatosensory perception and motor control training device for improving one of a somatosensory perception deficit and a motor control deficit for a human subject, said device comprising:

a probe capable of linear displacement;

an actuator coupled said probe;

a sensor coupled to said probe; and

a processor in electrical communication with said actuator and said sensor.

26. The computer-implemented method of claim 25 wherein the sensor is a force sensor.

27. The computer-implemented method of claim 26 wherein the force sensor is a binary force sensor.

28. The computer-implemented method of claim 27 further including a spring coupled to said probe.

29. The computer-implemented method of claim 25 wherein the sensor is a position sensor coupled to said probe.

30. The computer-implemented method of claim 25 wherein said processor is included in a computer.

31. The computer-implemented method of claim 30 wherein said device includes a second probe.

32. The computer-implemented method of claim 25 wherein said probe has a displacement range from 1 to 6 centimeters, a speed from 1 to 8 centimeters/second and a frequency of 0.01 to 10 Hertz.

33. The computer-implemented method of claim 25 wherein the motion of said probe follows a non-periodic waveform for an exercise implemented with said device.

34. A computer readable medium including instructions for improving one of a somatosensory perception and a motor control deficit for a human subject using a computer-implemented training apparatus, said instructions comprising:

(a) instructions for administering, using said computer-implemented training apparatus, a training regime including one of a set of somatosensory and motor control exercises to said human subject, said training regime having sufficient intensity to affect a lasting improvement in said one of a somatosensory perception and motor control deficit within said human subject;

(b) instructions for obtaining, using said computer-implemented training apparatus, a performance response of said human subject responsive to said one of a set of somatosensory and motor control exercises;

(c) instructions for altering, using said computer-implemented training apparatus, one or more parameters pertaining to said one of a set of somatosensory and motor control exercises, wherein said altering of said one or more parameters is performed responsive to said performance response and is configured to facilitate improving said one of a somatosensory perception and a motor control deficit within said human subject; and

(d) instructions for repeating at least (a) for a sufficient number of repetitions to affect said lasting improvement in said one of a somatosensory perception and a motor control deficit.

35. A computer implemented method for delivering computer readable instructions configured to improve one of a somatosensory perception and a motor control deficit for a human subject using a computer-implemented training apparatus, said instructions comprising:

(a) transmitting, over a signal transmission medium, signals representative of instructions for administering, using said computer-implemented training apparatus, a training regime including one of a set of somatosensory and motor control exercises to said human subject, said training regime having sufficient intensity to affect a lasting improvement in said one of a somatosensory perception and motor control deficit within said human subject;

(b) transmitting, over a signal transmission medium, signals representative of instructions for obtaining, using said computer-implemented training apparatus, a performance response of said human subject responsive to said one of a set of somatosensory and motor control exercises;

(c) transmitting, over a signal transmission medium, signals representative of instructions for altering, using said computer-implemented training apparatus, one or more parameters pertaining to said one of a set of somatosensory and motor control exercises, wherein said altering of said one or more parameters is performed responsive to said performance response and is configured to facilitate improving said one of a somatosensory perception and a motor control deficit within said human subject; and

(d) transmitting, over a signal transmission medium, signals representative of instructions for repeating at least (a) for a sufficient number of repetitions to affect said lasting improvement in said one of a somatosensory perception and a motor control deficit.

36. A computer-implemented method for improving one of a somatosensory perception and a motor control deficit for a human subject, said computer-implemented method comprising:

(a) receiving instructions from a first computer to execute a first set of code at a second computer, said first computer being coupled to said second computer via a computer network, said first set of code being configured to administer a training regime including one of a set of somatosensory and motor control exercises to said human subject, said training regime having sufficient intensity to affect a lasting improvement in said one of a somatosensory perception and motor control deficit within said human subject;

(b) transmitting computer commands from the second computer to the first computer to carry out the one of a set of somatosensory and motor control exercises at a user interface coupled to the first computer;

(c) obtaining, using the first computer, a performance response of said human subject responsive to said one of a set of somatosensory and motor control exercises;

(d) altering, using one of the first computer and the second computer, one or more parameters pertaining to said one of a set of somatosensory and motor control exercises, wherein said altering of said one or more parameters is performed responsive to said performance response and is configured to facilitate improving said one of a somatosensory perception and a motor control deficit within said human subject; and

(e) transmitting computer commands for repeating at least (a) for a sufficient number of repetitions to affect said lasting improvement in said one of a somatosensory perception and a motor control deficit.

37. The method of claim 36 further including providing said performance response to a health care professional using one of the first computer and the second computer.